Latest news articles

Added 1 month ago Drug news

Interim phase III analysis of DCVax-L in glioblastoma published in Journal of Translational Medicine.- Northwest Biotherapeutics.

Northwest Biotherapeutics announced the publication of interim blinded survival data from its Phase III clinical trial of DCVax-L (gene therapy)...

Added 4 months ago Drug news

Phase III GLOBE study of VB 111 + Avastin fails to meet endpoint in glioblastoma.- VBL Therapeutics.

VBL Therapeutics reported top-line results from its pivotal Phase III GLOBE study in patients with recurrent glioblastoma (rGBM) which was...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cushing's Syndrome

Cushing's Syndrome

Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

This update covers recommendations for glioblastoma; anaplastic astrocytoma, oligoastrocytoma and oligodendroglioma; and diffuse glioma. The recommendations cover clinically relevant problems in: diagnosis and pathology...

Added 4 years ago

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Journal articles

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

This Phase 3 trial evaluates the addition of an autologous tumor lysate-pulsed dendritic cell vaccine (DCVax®-L) to standard therapy for newly diagnosed glioblastoma.

Added 4 days ago

Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients.

Background: Embryonal tumor with multilayered rosettes (ETMR) is a rare and aggressive embryonal brain tumor that solely occurs in infants and young children and has only recently been recognized as a separate brain tumor entity...

Added 6 months ago

Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial.

The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown.

Added 10 months ago

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Clinical trials

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Added 1 year ago

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas (INTELLANCE 2)

This study is to evaluate the efficacy and safety of ABT-414 alone or with temozolomide versus temozolomide or lomustine alone in participants with recurrent glioblastoma multiforme.

Added 1 year ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Hallucinations - red flag symptoms

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MIMS Learning - Monthly Index of Medical Specialities
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Acoustic neuroma: clinical review

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MIMS Learning - Monthly Index of Medical Specialities
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Search all CME for Cancer of brain and nervous system