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Myasthenic crisis

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Published:1st Jan 2011
Author: Wendell LC, Levine JM.
Availability: Free full text
Ref.:Neurohospitalist. 2011 Jan;1(1):16-22.
DOI:10.1177/1941875210382918
Myasthenic crisis


Myasthenic crisis is a complication of myasthenia gravis characterized by worsening of muscle weakness, resulting in respiratory failure that requires intubation and mechanical ventilation. Advances in critical care have improved the mortality rate associated with myasthenic crisis. This article reviews the epidemiology of myasthenic crisis and discusses patient evaluation. Therapeutic options including mechanical ventilation and pharmacological and surgical treatments are also discussed.


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