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  • ,

    Anti-Infectives Knowledge Network (AIKN) IFI Updates

    Regularly updated with the latest evidence on invasive fungal infections, the most recent
    update to be added to the AIKN-IFI summarises the findings from a consensus of
    international experts on the management of intra-abdominal candidiasis.

    Healthcare professionals can view the recommendations for free; it can be found in the
    guidelines section of this resource.

    March 2015 MYC/15/0019/EUa

  • ,

    Anti-Infectives Knowledge Network (AIKN) CDI Updates

    Recently updated with ISICEM 2015 presentations, data from the largest ever European
    clinician consensus report, as well as key perspectives on Clostridium difficile infection
    (CDI).
    The Anti-Infectives Knowledge Network shares expertise and experience in the area of
    anti-infectives.

    This educational resource is an initiative by Astellas Pharma EMEA. Please remember
    to return often to read the news, clinical insights, and essential information from the
    latest anti-infectives congresses.

    March 2015 FDX/15/0024/EUb

  • ,

    New Therapy Focus area for
    type 2 diabetes launched

    This free resource has recently launched on epgonline.org containing information
    for healthcare professionals based in Europe on the use of incretin‐insulin treatment
    combinations for type 2 diabetes. Explore five informative sections focused on the role
    emerging incretin‐based therapies can play in the long‐term treatment and management of
    type 2 diabetes.

  • ,Whats's New Diabetes Knowledge Centre Relaunch

    Updated Type 2 Diabetes Mellitus Knowledge Centre

    Explore new information added to the diagnosis and treatment sections of the
    Type 2 Diabetes Mellitus Knowledge Centre with recommendations on the appropriate
    management of the condition. A brand new guidelines section is also available,
    containing the latest recommendations from ADA, EASD and NICE.

  • ,What's New Hypogonadism

    Hypogonadism Knowledge Centre

    epgonline.org’s Hypogonadism Knowledge Centre features a publications digest section,
    regularly updated with analysis and comment on recent scientific articles related to male
    hypogonadism.

    Found within the Men’s Health/Andrology disease topic homepage, users can also access
    information on the prevalence, diagnosis and available treatment options for male
    hypogonadism.

Latest News

Boston Scientific initiates REDUCE-HTN: REINFORCE study of Vessix V2 renal denervation system for hypertension.

20-Apr-2015

The first patient in the REDUCE-HTN: REINFORCE study was enrolled this week at Cardiology P.C. at Princeton Baptist Medical Center in Birmingham, Ala. by Farrell Mendelsohn, M.D., site principal investigator, and referred by Michael Wilensky, M.D. ...

ROADMAP results for HeartMate LVAD device for treatment of heart failure-Thoratec

20-Apr-2015

Thoratec Corporation announced results from the ROADMAP Study (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients). For the primary endpoint, a composite of ...

Keytruda (pembrolizumab) filed with FDA for marketing approval in NSCLC-Merck Inc

20-Apr-2015

Merck has submitted a supplemental Biologics License Application to the FDA for Keytruda (pembrolizumab), the company’s anti-PD-1 therapy, for the treatment of advanced non-small cell lung cancer (NSCLC). This initial filing seeks approval in the ...

Studies show ctDNA test effective in detecting EGFR NSCLC for treatment with Iressa-AstraZeneca

20-Apr-2015

AstraZeneca has presented results from two key studies showing the effectiveness of plasma circulating tumour DNA (ctDNA) testing for epidermal growth factor receptor (EGFR) mutation status in newly diagnosed patients with advanced non-small cell ...

CheckMate-057 trial of Opdivo (nivolumab) for NSCLC meets endpoint and is stopped early- BMS

19-Apr-2015

BMS announced that an open-label, randomized Phase III study (CheckMate -057) evaluating Opdivo (nivolumab) versus docetaxel in previously treated patients with advanced non-squamous non-small cell lung cancer (NSCLC) was stopped early because an ...

FDA approves the Itrevia DX ICD for Arrhythmias-Biotronik

19-Apr-2015

The FDA has approved the Itrevia DX implantable cardioverter defibrillator (ICD), from Biotronik, for patients with complex heart rhythm conditions. The Itrevia DX is a less invasive therapy with an algorithm that can identify successful pain-free ...

Further data for BAX 111 (highly-purified recombinant von Willebrand Factor) from Phase III study for von Willebrand disease-Baxter

19-Apr-2015

Baxter International Inc. presented additional data from the Phase III clinical trial of BAX 111, the first highly-purified recombinant von Willebrand Factor (rVWF) in clinical development as a treatment for patients with von Willebrand disease, the ...

Recent Updates

Drugs

Clinical Guidelines

Guidelines on Muscle-invasive and Metastatic Bladder Cancer

Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline

The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease

Guidelines on Urological Infections

Medical Journals

Identification of an anti-inflammatory derivative with anti-cancer potential: The impact of each of its structural components on inflammatory responses in macrophages and bladder cancer cells.

Prediction of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer

MAP Kinase Phosphatase 2 Regulates Macrophage-Adipocyte Interaction.

Obesity and risk of bladder cancer: a dose-response meta-analysis of 15 cohort studies.

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