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  • ,What's New IFI SOT Update

    Anti-Infectives Knowledge Network (AIKN) IFI Updates

    Regularly updated with the latest on invasive fungal infections, the most recent content
    to be added to the AIKN-IFI is published recommendations from the ESCMID Study Group
    for Infections in Compromised Hosts (ESGICH) for the prevention and management of
    infections in solid organ transplantation (SOT). Healthcare professionals can access a
    summary of these recommendations in the guidelines section of this resource.

    May 2015 MYC/15/0020/EUb

  • ,

    Anti-Infectives Knowledge Network (AIKN) CDI Updates

    Recently updated with ISICEM 2015 presentations, data from the largest ever European
    clinician consensus report, as well as key perspectives on Clostridium difficile infection
    (CDI). The Anti-Infectives Knowledge Network shares expertise and experience in the
    area of anti-infectives. This educational resource is an initiative by Astellas Pharma
    EMEA. Please remember to return often to read the news, clinical insights, and
    essential information from the latest anti-infectives congresses.

    March 2015 FDX/15/0024/EUb

  • ,

    New Therapy Focus area for
    type 2 diabetes launched

    This free resource has recently launched on epgonline.org containing information
    for healthcare professionals based in Europe on the use of incretin‐insulin treatment
    combinations for type 2 diabetes. Explore five informative sections focused on the role
    emerging incretin‐based therapies can play in the long‐term treatment and management of
    type 2 diabetes.

  • ,Whats's New Diabetes Knowledge Centre Relaunch

    Updated Type 2 Diabetes Mellitus Knowledge Centre

    Explore new information added to the diagnosis and treatment sections of the
    Type 2 Diabetes Mellitus Knowledge Centre with recommendations on the appropriate
    management of the condition. A brand new guidelines section is also available,
    containing the latest recommendations from ADA, EASD and NICE.

  • ,What's New Hypogonadism

    Hypogonadism Knowledge Centre

    epgonline.org’s Hypogonadism Knowledge Centre features a publications digest section,
    regularly updated with analysis and comment on recent scientific articles related to male
    hypogonadism.

    Found within the Men’s Health/Andrology disease topic homepage, users can also access
    information on the prevalence, diagnosis and available treatment options for male
    hypogonadism.

Latest News

CHMP recommends Evotec (atazanavir + cobicistat) for treatment of HIV-1- BMS

29-May-2015

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Evotaz (300 mg/150 mg) film coated tablets from BMS, intended for the treatment of ...

Talimogene laherparepvec Phase III OPTiM study results in metastatic melanoma published in Journal of Clinical Oncology- Amgen

29-May-2015

Amgen has announced the publication of primary results from the Phase III OPTiM study in the Journal of Clinical Oncology (JCO). The data published in JCO, which were previously presented at the Annual Meetings of the American Society of Clinical ...

FDA approves Humalog 200 units/mL KwikPen (U200)(insulin Lispro) for types 1 & 2 diabetes-Eli Lilly

28-May-2015

Eli Lilly and Company has announced that the FDA has approved Humalog 200 units/mL KwikPen (insulin lispro 200 units/mL; U-200), a pre-filled pen containing a concentrated formulation of Lilly's rapid-acting insulin Humalog (insulin lispro 100 ...

CHMP recommends Unituxin (dinutuximab) for neuroblastoma in children-United Therapeutics

28-May-2015

The CHMP has recommended granting a marketing authorisation for Unituxin (dinutuximab) from United Therapeutics for the treatment of high-risk neuroblastoma, a type of cancer that most often occurs in young children. Unituxin is to be used in ...

Early success of LentiGlobin in trial for sickle cell disease- bluebirdbio Inc.

27-May-2015

bluebird bio, Inc., a clinical-stage company committed to developing potentially transformative gene therapies for severe genetic and rare diseases and T cell-based immunotherapies, has announced that data from the ongoing Phase II HGB-205 study of ...

OTO 104 narrowly misses endpoints in Phase II trial for Ménière's disease but likely to progress to Phase III - Otonomy Inc.

27-May-2015

Otonomy, Inc. a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, announced topline results from its Phase IIb trial evaluating OTO-104 in patients with unilateral ...

Three Phase III studies support sarilumab in RA-Sanofi + Regeneron

27-May-2015

Sanofi and Regeneron Pharmaceuticals, Inc. announced that a Phase III study of sarilumab, an investigational, fully-human IL6 receptor antibody, met its co-primary efficacy endpoints of a greater improvement in signs and symptoms of rheumatoid ...

Recent Updates

Drugs

Clinical Guidelines

EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis

EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice

Guidelines on Muscle-invasive and Metastatic Bladder Cancer

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia. Part 3: Update 2015 Management of special circumstances: Depression, Suicidality, substance use disorders and pregnancy and lactation

Medical Journals

Cost-effectiveness of a behavioral intervention for persistent urinary incontinence in prostate cancer patients.

Androgen receptor: acting in the three-dimensional chromatin landscape of prostate cancer cells

4-D spatiotemporal analysis of ultrasound contrast agent dispersion for prostate cancer localization: a feasibility study.

Current role of multiparametric magnetic resonance imaging in the management of prostate cancer.

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