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Clinical trial

Extended Venous Thromboembolism Prophylaxis Comparing Rivaroxaban to Aspirin Following Total Hip and Knee Arthroplasty (EPCAT II)

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Last updated:24th Feb 2013
Identifier: NCT01720108

In this study the investigators want to look at whether using aspirin instead of rivaroxaban (after initial treatment with rivaroxaban) works as well at preventing blood clots while also reducing risk of bleeding and is more cost effective in patients who have either a total hip replacement or total knee replacement.


Study Type: Interventional  (Clinical Trial)
Actual Enrollment: 3426 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Extended Venous Thromboembolism Prophylaxis Comparing Rivaroxaban to Aspirin Following Total Hip and Knee Arthroplasty
Actual Study Start Date: February 24, 2013
Primary Completion Date: July 2016
Study Completion Date: July 2016

Arms and Interventions:
- Active Comparator:
rivaroxaban
- Experimental: ASA


Related journal:
- Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty.

Category Value
Date last updated at source 2018-01-25
Study type(s) Interventional
Expected enrolment 3426
Study start date 2013-02-24
Estimated primary completion date 2016-07-01

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