Latest news articles

Added 20 days ago Drug news

Zogenix will resubmit its NDA for Fintepla to treat seizures associated with Dravet syndrome in Q3 2019.

Zogenix, Inc.has announced that following receipt of final minutes from the FDA from the Type A meeting held on 30...

Added 24 days ago Drug news

FDA approves Symdeko for use in children with cystic fibrosis who have two copies of the F508del-CFTR mutation or who at least one mutation in the CFTR gene

Vertex Pharmaceuticals Incorporated announced the FDA approved Symdeko (tezacaftor/ivacaftor and ivacaftor) for use in children with cystic fibrosis ages 6...

Added 25 days ago Drug news

FDA accepts sBLA for Ultomiris to treat atypical hemolytic uremic syndrome (aHUS)

Alexion Pharmaceuticals, Inc. announced that the FDA has accepted for priority review the company’s supplemental Biologics License Application (sBLA) for...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

+ 1 more

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Crohn's disease: management

Crohn's disease is a chronic inflammatory disease that mainly affects the gastrointestinal tract. The disease may be progressive in some people, and a proportion may develop extra-intestinal manifestations.

Added 6 years ago

Lyme disease

This guideline covers diagnosing and managing Lyme disease. It aims to raise awareness of when Lyme disease should be suspected and ensure that people have prompt and consistent diagnosis and treatment.

Added 1 year ago

Epilepsies: diagnosis and management

The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.

Added 7 years ago

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Journal articles

In pursuit of control and elimination: update on hepatitis A and B epidemiology and prevention strategies.

Purpose of review: This review describes the impact of recommendations for routine immunization of infants and children against hepatitis A and hepatitis B, the changing epidemiology of these infections, and the remaining...

Added 7 days ago

A phase 3 study of tezacaftor in combination with ivacaftor in children aged 6 through 11 years with cystic fibrosis.

Background: Tezacaftor/ivacaftor is a new treatment option in many regions for patients aged ≥12 years who are homozygous (F/F) or heterozygous for the F508del-CFTR mutation and a residual function (F/RF) mutation.

Added 13 days ago

Delivering on the promise of gene editing for cystic fibrosis.

In this review, we describe a path for translation of gene editing into therapy for cystic fibrosis (CF). Cystic fibrosis results from mutations in the CFTR gene, with one allele predominant in patient populations.

Added 13 days ago

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Clinical trials

A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS) and to assess the pharmacokinetics (PK) of BIIB017 in pediatric participants...

Added 1 month ago

A Study to Evaluate Safety and Efficacy of Subcutaneous Administration of Anakinra in Patients With CF (ANAKIN)

Primary Ojective:
- To evaluate efficacy of treatment with anakinra in subjects with CF who are ≥ 12 years of age by means of lung clearance index (LCI).

Added 8 days ago

Symdeko in Cystic Fibrosis Patients

This clinical study will enroll 22 participants without the F508del mutation, carrying partial function mutations not approved for Symdeko, and who are not expected to be approved for CFTR modulator treatment in the immediate future.

Added 8 days ago

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Blog Posts

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 3 years ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

Am Ang Zhang

Autism: Challenges and Obstacles!

Posted 3 years ago

Retired child psychiatrist Am Ang Zhang discusses his experiences of working with the families of autistic children.

Am Ang Zhang

Autism: Frances Tustin and Entrenchment!

Posted 3 years ago

Am Ang Zhang discusses his work with pioneering child psychotherapist Frances Tustin, and his observations of entrenchment in autistic children.

CME

Management of nocturnal enuresis

Accrediting body
BMJ Learning - British Medical Learning
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90

Idiopathic constipation and nocturnal enuresis in childhood: a guide to management: putting NICE guidelines into practice

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BMJ Learning - British Medical Learning
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1
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90

Eczema in children: management and advice for parents

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
0
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1
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15
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