Latest news articles

Added 1 day ago Drug news

FDA and EMA accept filings of subcutaneous ofatumumab for the treatment of relapsing Multiple Sclerosis.- Genmab A/S + Novartis

Genmab A/S announced that the FDA has accepted, with priority review, the supplemental Biologics License Application (sBLA) submitted by Novartis...

Added 2 days ago Drug news

FDA accepts NDA for Libervant Buccal Film for the treatment of seizure clusters. -Aquestive Therapeutics.

Aquestive Therapeutics, Inc. announced that, as anticipated, the FDA accepted the Company’s New Drug Application (NDA) for Libervant (diazepam) Buccal...

Added 3 days ago Drug news

FDA approves Vyepti for migraine prevention.- Lundbeck

Lundbeck has announced that Vyepti (eptinezumab-jjmr) has been approved by the FDA for the preventive treatment of migraine in adults...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

EPNS 2019 Congress Highlights

EPNS 2019 Congress Highlights

The epgonline.org team is creating daily reports from the 13th European Paediatric Neurology Society (EPNS) Congress, held in Athens, Greece from 17th to 21st September 2019, to bring you coverage of cutting-edge science and advances in clinical care across all fields of paediatric neurology. 

Migraine Knowledge Centre

Migraine Knowledge Centre

The Migraine Knowledge Centre features latest research on the prevalence and impact of migraine, the proposed neurological basis of the condition (and how this is being translated into new and exciting drug therapies), as well as current patient care strategies collated from headache organisations worldwide.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

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Guidelines

Cannabis-based medicinal products

This guideline covers prescribing of cannabis-based medicinal products for people with intractable nausea and vomiting, chronic pain, spasticity and severe treatment-resistant epilepsy.

Added 2 months ago

Multiple sclerosis in adults: management

This guideline covers diagnosing and managing multiple sclerosis in people aged 18 and over. It aims to improve the quality of life for adults with multiple sclerosis by promoting symptom management...

Added 5 years ago

Epilepsies: diagnosis and management

The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.

Added 8 years ago

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Journal articles

Neuro-Bio-Behavioral Mechanisms of Placebo and Nocebo Responses: Implications for Clinical Trials and Clinical Practice.

The placebo effect has often been considered a nuisance in basic and particularly clinical research. This view has gradually changed in recent years due to deeper insight into the neuro-bio-behavioral mechanisms steering both...

Added 1 month ago

Personality functioning in adults with refractory epilepsy and community adults: Implications for health-related quality of life.

Introduction: Prior research has shown that people with epilepsy are at risk for a poorer health-related quality of life (HRQOL). However, patients differ greatly in how well they adjust to their epilepsy.

Added 1 month ago

Familial hemiplegic migraine with a PRRT2 mutation: Phenotypic variations and carbamazepine efficacy.

Objective: To understand the clinical characteristics of familial hemiplegic migraine (FHM) caused by a PRRT2 mutation and to examine the efficacy of preventive treatment.

Added 1 month ago

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Clinical trials

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

The primary objective of the study is to examine the clinical efficacy of nusinersen administered intrathecally at higher doses to participants with spinal muscular atrophy (SMA).

Added 5 months ago

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

This is a Phase 2 double-blind, randomized, placebo-controlled study to assess the safety and efficacy of ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC) in subjects with focal seizures...

Added 3 months ago

Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063) (ENLIGHTEN)

This is a multicenter, longitudinal, single-arm, open-label study to describe the change from baseline in cognitive processing speed, measured by the SDMT, in subjects with RMS treated with ozanimod HCl 1 mg at 3 years.

Added 3 months ago

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Blog Posts

Dr Cornelia Meisenberg

Progressive Supranuclear Palsy (PSP)

Posted 8 months ago

What is Progressive Supranuclear Palsy (PSP)? Review the causes, treatment and current trials for this uncommon, degenerative disorder.

Alex Keen

EPAD – Changing the way we think about Alzheimer’s prevention

Posted 1 year ago

We spoke to Professor Craig Ritchie of the University of Edinburgh, the poject co-coordinator for EPAD, a collaborative venture that is facilitating meaningful progress in preventative Alzheimer’s therapies. Find out more about the project, its methods, expectations and goals.

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 4 years ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

CME

Shoulder examination and diagnosis

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Tricyclic antidepressants and headaches: systematic review and meta-analysis

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Breaking bad news: a how to do it guide

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Search all CME for Neurology and CNS