Latest news articles

Added 1 month ago Drug news

European Commission approves Libtayo to treat advanced cutaneous squamous cell carcinoma

The European Commission (EC) has granted conditional marketing authorization for Libtayo (cemiplimab) from Regeneron + Sanofi for the treatment of...

Added 3 months ago Drug news

CHMP recommends approval of Libtayo for cutaneous squamous cell carcinoma

The European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion for the marketing authorization of Libtayo (cemiplimab)...

Added 4 months ago Drug news

Phase III trials underway to treat severe skin disease Gorlin Syndrome

PellePharm, Inc.,announced it has dosed the first patient in a pivotal Phase III clinical trial of Patidegib Topical Gel, 2%,...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Biosimilars Knowledge Centre

Biosimilars Knowledge Centre

What are biologics and how do they differ from small molecule medicines? Discover more about their development, as well as the manufacturing and regulatory processes in the Biosimilars in Oncology Knowledge Centre.

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Guidelines

Management of primary cutaneous squamous cell carcinoma

This guideline provides recommendations for referral, management and follow up of patients aged 18 years and over with primary invasive SCC, including SCC arising: on sun-exposed (SE) and non-SE sites.

Added 5 years ago

British Association of Dermatologists’ guidelines for the management of squamous cell carcinoma in situ (Bowen’s disease) 2014

The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the management of squamous cell carcinoma (SCC) in situ (Bowen’s disease).

Added 5 years ago

Guidelines for the management of basal cell carcinoma

This article represents a planned regular updating of the previous British Association of Dermatologists guidelines for the management of basal cell carcinoma.

Added 11 years ago

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Journal articles

PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma.

Background: No systemic therapies have been approved for the treatment of advanced cutaneous squamous-cell carcinoma. This cancer may be responsive to immune therapy, because the mutation burden of the tumor is high...

Added 1 year ago

Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial.

Background: Merkel cell carcinoma is a rare, aggressive skin cancer with poor prognosis in patients with advanced disease. Current standard care uses various cytotoxic chemotherapy regimens...

Added 1 year ago

Avelumab and other recent advances in Merkel-cell carcinoma.

Merkel-cell carcinoma (MCC) is a rare but aggressive form of skin cancer that occurs in the elderly, is associated with UV radiation and immunosuppression. Initial treatment consists of wide excision with adjuvant radiation.

Added 1 year ago

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Clinical trials

Avelumab in Subjects With Merkel Cell Carcinoma (JAVELIN Merkel 200)

This is a multicenter, international, single-arm, open-label, Phase 2 trial to evaluate the efficacy and safety of avelumab in subjects with metastatic Merkel cell carcinoma (MCC).

Added 1 year ago

A Phase II Study of Efficacy and Safety in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma (BOLT)

This study will assess the efficacy and safety of oral treatment with two dose levels of LDE225 in patients with locally advanced or metastatic BCC.

Added 9 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Leg ulcers - red flag symptoms

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MIMS Learning - Monthly Index of Medical Specialities
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Urgent referrals in dermatology

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MIMS Learning - Monthly Index of Medical Specialities
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Search all CME for Non-epithelial cancer of skin