Latest news articles

Added 8 hours ago Drug news

FDA accepts NDA for Libervant Buccal Film for the treatment of seizure clusters. -Aquestive Therapeutics.

Aquestive Therapeutics, Inc. announced that, as anticipated, the FDA accepted the Company’s New Drug Application (NDA) for Libervant (diazepam) Buccal...

Added 15 days ago Drug news

Positive top-line results from pivotal phase III trial of Fintepla to treat Lennox-Gastaut Syndrome.- Zogenix

Zogenix, Inc.reported positive top-line results from its global Phase III clinical trial (Study 1601) of its lead investigational therapy, Fintepla...

Added 1 month ago Drug news

Additional indications in Japan for Fycompa for partial-onset seizures. Eisai

Eisai Co., Ltd.announced that it has obtained the approvals of supplementary new drug applications in Japan for its in-house developed...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hereditary ATTR amyloidosis

Hereditary ATTR amyloidosis

Explore the pathophysiology, epidemiology and multi-system symptoms associated with hereditary ATTR amyloidosis, as well as how to achieve an early and accurate diagnosis.

EPNS 2019 Congress Highlights

EPNS 2019 Congress Highlights

The epgonline.org team is creating daily reports from the 13th European Paediatric Neurology Society (EPNS) Congress, held in Athens, Greece from 17th to 21st September 2019, to bring you coverage of cutting-edge science and advances in clinical care across all fields of paediatric neurology. 

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Guidelines

Cannabis-based medicinal products

This guideline covers prescribing of cannabis-based medicinal products for people with intractable nausea and vomiting, chronic pain, spasticity and severe treatment-resistant epilepsy.

Added 2 months ago

Epilepsies: diagnosis and management

The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.

Added 8 years ago

Suspected neurological conditions: recognition and referral

This guideline covers the initial assessment of symptoms and signs that might indicate a neurological condition. It helps non-specialist healthcare professionals to identify people who should be offered referral for specialist investigation.

Added 6 months ago

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Journal articles

Personality functioning in adults with refractory epilepsy and community adults: Implications for health-related quality of life.

Introduction: Prior research has shown that people with epilepsy are at risk for a poorer health-related quality of life (HRQOL). However, patients differ greatly in how well they adjust to their epilepsy.

Added 1 month ago

Central nervous system adverse effects of new antiepileptic drugs. A meta-analysis of placebo-controlled studies.

Objective: Systematic review and meta-analysis of the most frequent treatment-emergent central nervous system adverse events (CNS AEs) of new antiepileptic drugs (AEDs) from double-blind, add-on, placebo-controlled studies...

Added 1 month ago

Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics.

This report provides a comprehensive foundation of an approach to infants with seizures, while identifying where there are inadequate data to support recommended practice, and where further data collection is needed to address these deficits.

Added 1 month ago

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Clinical trials

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

This is a Phase 2 double-blind, randomized, placebo-controlled study to assess the safety and efficacy of ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC) in subjects with focal seizures...

Added 2 months ago

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure frequency in participants with pediatric epileptic syndrome...

Added 4 months ago

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

The purpose of the study is to evaluate the efficacy, safety and tolerability of the 3 selected dose regimens of padsevonil (PSL) administered concomitantly with up to 3 anti-epileptic drugs (AEDs) compared with placebo for treatment...

Added 8 months ago

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CME

Epilepsy: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
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1
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90

Hallucinations - red flag symptoms

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
0
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1
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0

Epilepsy: clinical review

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
2
Registration required
1
Subscription fee
0
Search all CME for Epilepsy, convulsions