Latest news articles

Added 3 days ago Drug news

Braftovi triplet combination success in BEACON CRC trial in patients with BRAFV600E-mutant metastatic colorectal cancer

Array BioPharma Inc. announced positive results from the interim analysis of the Phase III BEACON CRC trial evaluating the combination...

Added 14 days ago Drug news

Study of Signatera ctDNA assay in colorectal cancer published in JAMA Oncology

A new clinical study shows that Natera's Signatera ctDNA assay identified colorectal cancer recurrence up to 16.5 months earlier than...

Added 28 days ago Drug news

Tecentriq and Cotellic combination fails Phase III trial to treat microsatellite-stable colorectal cancer

Tecentriq and Cotellic combination failed to improve survival over standard third-line therapy for patients with chemorefractory metastatic colorectal cancer (CRC)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Inflammatory Bowel Disease Knowledge Centre

Inflammatory Bowel Disease Knowledge Centre

The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and unmet needs and the underlying inflammatory processes that drive IBD, considering some of the key inflammatory pathways.

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Guidelines

Diagnosis and management of colorectal cancer

This guideline covers diagnosis and treatment of colorectal cancer. It summarises the evidence and, where appropriate, provides evidence-based recommendations...

Added 7 years ago

Colorectal cancer: diagnosis and management

This guideline covers diagnosing and managing colorectal (bowel) cancer in people aged 18 and over.

Added 7 years ago

Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline

This is an official guideline of the European Society of Gastrointestinal Endoscopy (ESGE) and the European Society of Gastrointestinal and Abdominal Radiology (ESGAR). It addresses the clinical indications for the use of...

Added 4 years ago

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Journal articles

Regorafenib: A Review in Metastatic Colorectal Cancer.

Regorafenib (Stivarga®) is an oral small-molecule multiple kinase inhibitor. It is indicated worldwide for patients with metastatic colorectal cancer (mCRC).

Added 9 months ago

Regorafenib therapy in metastatic colorectal cancer patients: markers and outcome in an actual clinical setting.

The oral multikinase inhibitor regorafenib had beneficial effects in randomized clinical phase III trials compared to the placebo in patients with metastatic colorectal cancer (mCRC) who progressed on standard therapies.

Added 9 months ago

Colon cleansing efficacy and safety with 1 L NER1006 versus 2 L polyethylene glycol + ascorbate: a randomized phase 3 trial.

Background: Polyethylene glycol (PEG)-based bowel preparations are effective cleansers but many require high-volume intake. This phase 3, randomized, blinded, multicenter, parallel-group, central reader-assessed study...

Added 10 months ago

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Clinical trials

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 1 year ago

Laparoscopic Surgery for T4 Tumor of the Colon Cancer (LST4C Trial)

The purpose of this study is to compare the short- and long-term survival of laparoscopic surgery and conventional open surgery for T4 colon cancer.

Added 1 year ago

Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer (BEACON CRC)

This is a multicenter, randomized, open-label, 3-arm Phase 3 study to evaluate encorafenib + cetuximab plus or minus binimetinib versus Investigator's choice of either irinotecan/cetuximab or FOLFIRI/cetuximab...

Added 10 months ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Association of adherence to lifestyle recommendations and risk of colorectal cancer: a prospective Danish cohort study

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
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1
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90
Search all CME for Cancer of colon