832 Results

Diagnostic properties of total and free prostate-specific antigen to predict overall and clinically significant prostate cancer among men with low testosterone and prior negative biopsy.

Objective: To evaluate whether total serum PSA, free-PSA ratio and PSA density have similar diagnostic properties for detecting prostate cancer (PCa) and clinically-significant (cs) PCa in men with normal testosterone compared...

Role of Androgen Receptor in Prostate Cancer: A Review.

This review focuses on the functions of AR in prostate cancer and the development of CRPC and promising new agents against CRPC.

Increased expression of miR-153 predicts poor prognosis for patients with prostate cancer.

Deregulation of miR-153 has recently been observed in several common human cancer, while miR-153 serves an oncogene or tumor suppressive role in different cancer types. Previously, miR-153 has been identified to be overexpressed in...

Prostate radiotherapy in newly diagnosed metastatic prostate cancer.

Purpose of review: The aim of this article is to review the role of prostate radiotherapy in the multimodal management of newly diagnosed metastatic hormone naïve prostate cancer.

Exploitation of CD133 for the targeted imaging of lethal prostate cancer.

Purpose: Aggressive variant prostate cancer (AVPC) is a non-androgen receptor-driven form of disease that arises in men who have failed standard-of-care therapies. Therapeutic options for AVPC are limited, and the development of...

Prostate-specific membrane antigen guided surgery.

Since its introduction in the diagnostic pathway of prostate cancer management, prostate-specific membrane antigen (PSMA)-ligand positron-emission tomography (PET) has demonstrated great potential.

Prostate cancer in young men: An emerging young adult and older adolescent challenge.

Background: Recent observations suggest that prostate cancer is an increasing disease among older adolescents and young adults.

Emerging therapeutic targets for patients with advanced prostate cancer.

Although recent advances in the treatment of castration-resistant prostate cancer (CRPC) have significantly improved patient outcomes, advanced prostate cancer is still associated with substantial morbidity and mortality, particularly...

Androgen deprivation therapy in nonmetastatic prostate cancer patients: Indications, treatment effects, and new predictive biomarkers.

Men with prostate cancer with positive margins, extraprostatic extension, positive lymph nodes, high prostateā€specific antigen, or high Gleason Score are at high risk of recurrence following primary therapy. Androgen deprivation therapy...

Diet and lifestyle considerations for patients with prostate cancer.

Purpose: To review the literature and provide recommendations on diet and lifestyle considerations in patients with prostate cancer using evidence from randomized controlled trials (RCTs) with additional considerations...

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