Latest news articles

Added 4 days ago Drug news

Actelion Pharma withdraws filing of Opsumit for CTEPH

Actelion Pharmaceuticals Ltd, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, has announced its decision to voluntarily withdraw...

Added 15 days ago Drug news

Uvadex is approved in Australia for use with the Therakos Cellex Photopheresis System for treatment of chronic graft versus host disease (cGvHD) and skin manifestations of cutaneous T-cell lymphoma in adults. Mallinckrodt

Mallinckrodt Plc announced that Uvadex (methoxsalen) has received regulatory approval in Australia by the Therapeutic Goods Administration (TGA) for extracorporeal...

Added 16 days ago Drug news

FDA grants appeal for N 1539 complete response for treatment of moderate to severe pain.- Recro Pharma

Recro Pharma announced that it has received a written decision from the FDA granting its appeal of the Complete Response...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

This guideline covers assessing and reducing the risk of venous thromboembolism (VTE or blood clots) and deep vein thrombosis (DVT) in people aged 16 and over in hospital.

Added 9 years ago

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart R

The scope of this focused update of the 2014 AF Guideline includes revisions to the section on anticoagulation (because of the approval of new medications and thromboembolism protection devices), revisions to the section...

Added 3 months ago

Urinary incontinence and pelvic organ prolapse in women: management

This guideline covers assessing and managing urinary incontinence and pelvic organ prolapse in women aged 18 and over. It also covers complications associated with mesh surgery for these conditions.

Added 3 months ago

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Journal articles

Proximal spinal muscular atrophy: current orthopedic perspective.

Spinal muscular atrophy (SMA) is a hereditary neuromuscular disease of lower motor neurons that is caused by a defective "survival motor neuron" (SMN) protein that is mainly associated with proximal progressive muscle weakness and atrophy.

Added 12 days ago

Outcomes of liver transplantation for non-alcoholic steatohepatitis: A European Liver Transplant Registry study.

Background & Aims: Little is known about outcomes of liver transplantation for patients with non-alcoholic steatohepatitis (NASH). We aimed to determine the frequency and outcomes of liver transplantation for patients...

Added 23 days ago

Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH).

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries with almost 25% affected adults worldwide. The growing public health burden is getting evident when considering that...

Added 23 days ago

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Clinical trials

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement (HYPALB)

The primary objective of this study is to test the effect of 20% albumin on plasma volume expansion and fluid recruitment in the frame of blood loss replacement during cystectomy using established fluid kinetic models.

Added 7 months ago

This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding

The primary objective is to demonstrate reversal of the anticoagulant effect of dabigatran in patients treated with dabigatran etexilate who have uncontrolled or life-threatening bleeding requiring urgent intervention, and in patients treated...

Added 5 months ago

Adjusted Fibrinogen Replacement Strategy (AdFIrst)

The purpose of this study is to investigate efficacy and safety of fibrinogen concentrate BT524, when administered to patients with major blood loss during elective spine surgery.The study aims to demonstrate that BT524 is at least...

Added 4 months ago

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Blog Posts

Professor Gerhard Pƶlzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 2 years ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

Hugh Harvey

Metrics Madness

Posted 4 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Yuli Pramana

Choosing Between Endoscopic Sclerotherapy And Endoscopic Ligation For Esophageal Varices

Posted 4 years ago

Endoscopic Sclerotherapy (ES) and Endoscopic Ligation (EL) were accepted in the treatment of esophageal varices bleeding in patients with liver cirrhosis. EL seemed to be superior to ES. If EL was difficult then ES should be performed.

CME

Fluid management in acutely ill patients

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
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1
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90

Assessing patients for minor surgery

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
0
Registration required
1
Subscription fee
15

Hidradenitis suppurativa: diagnosis and management

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
1
Registration required
1
Subscription fee
0
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