Latest news articles

Added 12 hours ago Drug news

Phase III ATLAS study success for two-drug regimen ,namely cabotegravir and rilpivirine, for the treatment of HIV compared with continuing a three-drug oral regimen. ViiV HealthCare + Janssen Therapeutics.

ViiV Healthcare announced positive headline results from its global, phase III ATLAS study of a long-acting, injectable two-drug regimen (2DR)...

Added 5 days ago Drug news

FDA approves Annovera first one year contraceptive.- The Population Council + TherapeuticsMD.

The Population Council, a global nonprofit research organization, announced it has received FDA approval for Annovera (segesterone acetate and ethinyl...

Added 15 days ago Drug news

New switch data reinforcing Symtuza for treatment of HIV-1 regardless of prior regimen and for initiating the drug in the newly diagnosed.- Janssen Pharma.

The Janssen Pharmaceutical Companies of Johnson & Johnson announced new data reinforcing the safety and efficacy of switching to Symtuza...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

EASL Recommendations on Treatment of Hepatitis C 2018

These European Association for the Study of the Liver Recommendations on Treatment of Hepatitis C describe the optimal management of patients with acute and chronic HCV infections in 2018 and onwards.

Added 1 month ago

Guidelines on Penile Cancer

The European Association of Urology (EAU) Guidelines on Penile Cancer provides up-to-date information on the diagnosis and management of penile squamous cell carcinoma (SCC).

Added 4 years ago

Heavy menstrual bleeding: assessment and management

This guideline covers assessing and managing heavy menstrual bleeding (menorrhagia).

Added 11 years ago

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Journal articles

Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer.

We hypothesized that enzalutamide, which prolongs overall survival among patients with metastatic, castration-resistant prostate cancer, would delay metastasis in men with nonmetastatic...

Added 1 month ago

Darunavir for the treatment of HIV infection.

The authors present and discuss the efficacy and safety data of DRV when used in antiretroviral-naïve, multiexperienced subjects and in the setting of treatment deintensification in subjects with viral suppression.

Added 1 month ago

Switching to fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide from dolutegravir plus abacavir and lamivudine in virologically suppressed adults with HIV-1: 48 week results of a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.

Bictegravir, co-formulated with emtricitabine and tenofovir alafenamide, has shown good efficacy and tolerability, and similar bone, renal, and lipid profiles to dolutegravir, abacavir, and lamivudine, in treatment-naive adults with HIV-1...

Added 1 month ago

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Clinical trials

An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)

This study will compare safety, efficacy, and tolerability of a two drug regimen of dolutegravir (DTG) plus (+) lamivudine (3TC) administered once daily with DTG plus two nucleoside reverse transcriptase inhibitors...

Added 1 month ago

An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir (DTG) Plus Lamivudine (3TC) With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 2)

This study will compare safety, efficacy, and tolerability of a two drug regimen of dolutegravir (DTG) plus (+) lamivudine (3TC) administered once daily with DTG plus two nucleoside reverse transcriptase inhibitors...

Added 1 month ago

Miami Membrane for Potency (MMEP) Trial (MMEP)

The use of dehydrated human amnionic membrane allograft will result in an absolute 20% increase (from 40-60%) in the proportion...

Added 3 years ago

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Blog Posts

Monica Caliber

Hypogonadism – why important to diagnose and treat?

Posted 2 years ago

Most clinicians and patients think that the purpose of treating hypogonadism is to merely relieve symptoms. However, this only scratches the surface... 

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Breaking bad news: a how to do it guide

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Zika virus

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Pelvic organ prolapse

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