Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

IL-17A in Psoriasis

IL-17A in Psoriasis

Experts discuss new targeted therapies for psoriasis at the European Association of Dermatology and Venereology (EADV) Congress.

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Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

Lyme disease

This guideline covers diagnosing and managing Lyme disease. It aims to raise awareness of when Lyme disease should be suspected and ensure that people have prompt and consistent diagnosis and treatment.

Added 8 days ago

The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults

The aim of this guideline was to produce recommendations for the management of adult lupus patients in the UK that cover the diagnosis, assessment and monitoring of lupus and the treatment of mild, moderate and severe active lupus disease...

Added 3 months ago

The British Society for Rheumatology guideline for the management of adults with primary Sjögren’s Syndrome

This document aims to provide a pragmatic, practical guideline for the management of adults with pSS.

Added 3 months ago

Search all guidelines for Rheumatology
 

Journal articles

Efficacy and safety of guselkumab in patients with active psoriatic arthritis: a randomised, double-blind, placebo-controlled, phase 2 study.

Background: Guselkumab, a human monoclonal antibody that binds to the p19 subunit of interleukin 23, has been approved for the treatment of moderate-to-severe psoriasis.

Added 5 days ago

Efficacy and safety of interleukin-1 antagonists in rheumatoid arthritis: a systematic review and meta-analysis.

Rheumatoid arthritis patients have a high level of pro-inflammatory interleukin-1. Augmenting the blockade of interleukin-1 receptors by external interleukin-1 receptor antagonist modifies the progression of the disease.

Added 1 month ago

The emerging role of IL-1 inhibition in patients affected by rheumatoid arthritis and diabetes.

Objective: We reviewed the role of IL-1β during RA and T2D, the efficacy of IL-1 blocking agents in controlling both diseases and, possible, decreasing the concomitant enhanced atherosclerotic process.

Added 1 month ago

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Clinical trials

Inhibition of Co-Stimulation in Rheumatoid Arthritis (ICoSRA)

The purpose of this study is to use abatacept as a clinical molecular probe to evaluate the effects of inhibiting...

Added 3 years ago

A Study Comparing ABT-494 to Placebo and to Adalimumab in Subjects With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate (SELECT-COMPARE)

This is a phase 3, randomized, double-blind study comparing ABT-494 to Placebo and to Adalimumab in subjects with moderately to...

Added 3 years ago

Efficacy and Safety of Sarilumab and Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (SARIL-RA-MONARCH)

Primary Objective:
- To demonstrate that sarilumab monotherapy is superior to adalimumab monotherapy with respect to signs and symptoms as assessed by disease activity score 28...

Added 4 years ago

Search all clinical trials for Rheumatology
 

Blog Posts

Alex Keen

EULAR 2018 – Biosimilars: the future of rheumatology?

Posted 12 days ago

EULAR's Annual European Congress of Rheumatology aims to encourage innovation and collaboration across all aspects of rheumatology, something that is particularly well illustrated by biologics and their more affordable counterpart, biosimilars. Could they unlock the door to accessible, life-changing treatment for millions more?

Lauren McCracken

EAACI hot topics: Allergen specific immunotherapy (AIT)

Posted 14 days ago

When should AIT be used to treat your patients with allergies? Is it right for every allergy? And do we really know the long-term effects of this treatment? This blog highlights some of the talking points surrounding AIT discussed at this year’s EAACI Congress.

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

10 minute consultation: Plantar heel pain

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
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Childhood obesity: a guide on diagnosis, prevention and management

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
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90

Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
0
Registration required
1
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90
Search all CME for Rheumatology