Latest news articles

Added 12 days ago Drug news

Janssen Pharma files NDA at FDA for esketamine nasal spray to treat treatment-resistant depression.

The Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) announced the submission of a New Drug Application (NDA) to the...

Added 14 days ago Drug news

Complete Response Letter for dasotraline to treat ADHD.- Sunovion Pharma.

Sunovion Pharmaceuticals Inc. announced that the FDA issued a Complete Response Letter for the New Drug Application (NDA) for dasotraline,...

Added 15 days ago Drug news

Analysis of three studies of Zulresso (brexanolone injection) in postpartum depression published in the Lancet.- Sage Therapeutics.

Sage Therapeutics announced The Lancet has published an integrated analysis across three, double-blind, randomized, placebo-controlled studies of Zulresso (brexanolone injection)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Antenatal and postnatal mental health: clinical management and service guidance

This guideline covers recognising, assessing and treating mental health problems in women who are planning to have a baby, are pregnant, or have had a baby or been pregnant in the past year.

Added 3 years ago

Depression in adults: recognition and management

This guideline covers identifying and managing depression in adults aged 18 years and older, in primary and secondary care.

Added 8 years ago

Stop smoking interventions and services

This guideline covers stop smoking interventions and services delivered in primary care and community settings for everyone over the age of 12.

Added 3 months ago

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Journal articles

Effectiveness of paliperidone long-acting injection in clinical practice.

Background: The efficacy of the long-acting injectable formulation of the antipsychotic paliperidone (paliperidone palmitate) has been investigated in randomized controlled trials.

Added 2 months ago

Efficacy and safety profile of paliperidone palmitate injections in the management of patients with schizophrenia: an evidence-based review.

This review focuses on paliperidone palmitate, the long-acting injectable (LAI) formulation of paliperidone. After considering the pharmacology of paliperidone palmitate, we review the randomized controlled trials...

Added 2 months ago

Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes.

Introduction: There are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package...

Added 2 months ago

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Clinical trials

Pharmacologic Treatment of Acute Episode of Schizophrenia: a Real World Study

This study attempts to observe the effectiveness and safety of aripiprazole in hospitalized patients with acute schizophrenia episode, and to compare the different drug regimens that may be involved in order to clarify the characteristics...

Added 10 months ago

A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder

This study will evaluate the safety and tolerability of brexpiprazole (OPC-34712) in the treatment of subjects with bipolar I disorder. All subjects will receive a starting dose of brexpiprazole which will be titrated up in subsequent visits.

Added 10 months ago

Study to Evaluate Safety & Efficacy of NaBenĀ® as Add-on Treatment for Schizophrenia in Adults

The proposed Phase IIb/III study is designed to evaluate the safety and efficacy of NaBen® in improving the symptoms of schizophrenia in adults. NaBen® is granted Breakthrough Therapy Designation by US FDA as add-on treatment...

Added 10 months ago

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Blog Posts

Christopher Paul Jones

Dealing with mental health issues using integrated approaches, including tech and apps

Posted 1 year ago

As healthcare professionals are well aware, a significant percentage of the population (approximately one in four) will suffer a mental health problem at some point in their lives. In the course of his work, Christopher Paul Jones is finding that people are increasingly looking for alternatives to, or approaches to complement, pharmaceutical drugs to manage their conditions, and that tech and apps are proving very useful indeed. He feels it is particularly useful for those whose location or financial status might otherwise prohibit them from integrated strategies. Here is what he has to say:

Am Ang Zhang

Autism: Challenges and Obstacles!

Posted 2 years ago

Retired child psychiatrist Am Ang Zhang discusses his experiences of working with the families of autistic children.

Am Ang Zhang

Autism: Frances Tustin and Entrenchment!

Posted 2 years ago

Am Ang Zhang discusses his work with pioneering child psychotherapist Frances Tustin, and his observations of entrenchment in autistic children.

CME

Tricyclic antidepressants and headaches: systematic review and meta-analysis

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Post-traumatic stress disorder

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Credits available
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90

Depression in adults with a chronic health problem: putting NICE guidelines into practice

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Union of European Medical Specialists (via European Accreditation Council for CME)
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1
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1
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90
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