Latest news articles

Added 11 days ago Drug news

Sage Therapeutics announces development plan for zuranolone following meeting with the FDA.

Sage Therapeutics, Inc. announced next steps in the Landscape Program, the clinical program evaluating zuranolone (SAGE-217) for the treatment of...

Added 19 days ago Drug news

CE Mark for Symmetry vagus nerve stimulation therapy to treat depression. - LivaNova PLC

LivaNova PLC a market-leading medical technology and innovation company, announced its Vagus Nerve Stimulation Therapy (VNS Therapy) System, Symmetry, earned...

Added 23 days ago Drug news

vorvida is filed at FDA by Orexo AB to treat alcohol use disorder .

Orexo AB (publ), announces it has submitted an application to the FDA for vorvida to enable commercialization in the US....

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Optimising anti-TNF treatment using biosimilars

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Attention deficit hyperactivity disorder: diagnosis and management

This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder (ADHD) in children, young people and adults.

Added 11 years ago

Generalised anxiety disorder and panic disorder in adults: management

This guideline covers the care and treatment of people aged 18 and over with generalised anxiety disorder (chronic anxiety) or panic disorder (with or without agoraphobia or panic attacks).

Added 9 years ago

Depression in children and young people: identification and management

This guideline covers the identification and treatment of depression in children (5–11 years) and young people (12–18 years) in primary, community and secondary care.

Added 14 years ago

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Journal articles

Epidemiology of mental health comorbidity in psoriasis.

Aim: The occurrence of mental health comorbidities such as depression, anxiety, and suicidal ideation or behavior is not uncommon in the context of psoriasis. The negative influence of psoriatic disease on a patient’s...

Added 2 months ago

Esketamine: A Novel Option for Treatment-Resistant Depression.

Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, use requirements, and place in therapy of esketamine for treatment-resistant depression (TRD).

Added 2 months ago

Efficacy and safety of intranasal esketamine for the treatment of major depressive disorder.

Introduction: In March 2019, intranasal esketamine was approved by the Food and Drug Administration (FDA) for the treatment of treatment-resistant depression (TRD) in adults. This review presents the results of clinical trials...

Added 2 months ago

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Clinical trials

Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson's Disease With Neuropsychiatric Symptoms Treated With Pimavanserin or Low-Dose Quetiapine

This is a pilot, hypothesis-generating study to explore the effects of pimavanserin and low-dose quetiapine in subjects with Parkinson's disease with neuropsychiatric symptoms.

Added 4 months ago

Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia With Lewy Bodies (AscenD-LB)

This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, proof-of-principle study of neflamapimod versus matching placebo (randomized 1:1) administered with food for 16 weeks in subjects with DLB.

Added 4 months ago

A Study to Evaluate Safety of Long-term AL001 Dosing in FTD Patients

A Phase 2 open label study evaluating the safety, tolerability, PK and PD of AL001 in participants with a Granulin mutation or C9orf72 mutation causative of frontotemporal dementia.

Added 4 months ago

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Blog Posts

Christopher Paul Jones

Dealing with mental health issues using integrated approaches, including tech and apps

Posted 2 years ago

As healthcare professionals are well aware, a significant percentage of the population (approximately one in four) will suffer a mental health problem at some point in their lives. In the course of his work, Christopher Paul Jones is finding that people are increasingly looking for alternatives to, or approaches to complement, pharmaceutical drugs to manage their conditions, and that tech and apps are proving very useful indeed. He feels it is particularly useful for those whose location or financial status might otherwise prohibit them from integrated strategies. Here is what he has to say:

Am Ang Zhang

Autism: Challenges and Obstacles!

Posted 4 years ago

Retired child psychiatrist Am Ang Zhang discusses his experiences of working with the families of autistic children.

Am Ang Zhang

Autism: Frances Tustin and Entrenchment!

Posted 4 years ago

Am Ang Zhang discusses his work with pioneering child psychotherapist Frances Tustin, and his observations of entrenchment in autistic children.

CME

Tricyclic antidepressants and headaches: systematic review and meta-analysis

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Post-traumatic stress disorder

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Depression in adults with a chronic health problem: putting NICE guidelines into practice

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Union of European Medical Specialists (via European Accreditation Council for CME)
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