Latest news articles

Added 12 days ago Drug news

FDA approves Exparel sNDA for postsurgical regional analgesia.- Pacira Pharma.

Pacira Pharmaceuticals, Inc. announced that the FDA has approved its supplemental new drug application (sNDA) to broaden the use of...

Added 1 month ago Drug news

Phase III GLOBE study of VB 111 + Avastin fails to meet endpoint in glioblastoma.- VBL Therapeutics.

VBL Therapeutics reported top-line results from its pivotal Phase III GLOBE study in patients with recurrent glioblastoma (rGBM) which was...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Management of toxicities from immunotherapy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Immunotherapy is an essential component of cancer care and expands the treatment possibilities for patients. Immune checkpoint inhibitors are among the most promising drugs but are associated with toxicities.

Added 6 months ago

Management of infusion reactions to systemic anticancer therapy: ESMO Clinical Practice Guidelines

Most anticancer treatments carry a risk for infusion reactions which incidence may increase when different agents are administered concomitantly.

Added 6 months ago

Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conference

The guidelines on antiemetics provide an update on the classification of the emetogenic potential of antineoplastic agents, adding 42 new drugs many of which are orally administered. The recommendations for the prophylaxis of nausea and vomiting...

Added 8 years ago

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Journal articles

Fentanyl Formulations in the Management of Pain: An Update.

The aim of this review is to provide an update on current non-parenteral fentanyl formulations, with attention to their particular pharmacokinetics and features relevant to clinical use in pain management.

Added 1 month ago

The use of rapid onset fentanyl in children and young people for breakthrough cancer pain.

The primary aim of this study was to assess whether there is a correlation between effective dose of rapid onset fentanyl and background oral morphine equivalent analgesia in children less than 18 years old.

Added 1 month ago

Fentanyl buccal tablet for breakthrough cancer pain in clinical practice: results of the non-interventional prospective study ErkentNIS.

BTcP is pain exacerbation despite opioid baseline therapy. Fentanyl buccal tablet (FBT) is a rapid-onset opioid for the treatment of BTcP. The aim of this study is to document the feasibility of FBT in patients with BTcP.

Added 2 months ago

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Clinical trials

Melatonin Oral Gel for Oral Mucositis in Patients With Head and Neck Cancer Undergoing Chemoradiation (MUCOMEL)

The main purpose of this study is to assess the efficacy of melatonin oral gel compared to placebo in the...

Added 3 years ago

Early Palliative Care in Metastatic Lung Cancer in Northern France (IMPAQ)

Single-center, prospective, controlled, open-label, randomized, two parallel arms comparing early Palliative care versus Standard care in patients with non-small-cell metastatic...

Added 4 years ago

PROject - Supportive and Palliative Care and INnOvation - Antwerp (Pro-Spinoza) (pro-Spinoza)

It is important to provide high quality palliative care to all patients with a non-curable and life-limiting condition. The Care...

Added 4 years ago

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Blog Posts

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Association of adherence to lifestyle recommendations and risk of colorectal cancer: a prospective Danish cohort study

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Depression in adults with a chronic health problem: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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Palliative care in patients with heart failure

Accrediting body
BMJ Learning - British Medical Learning
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