Data from multiple sources - Curated by Marshall Pearce - Last updated 06 June 2017

Latest news articles

Added 6 days ago Drug news

FDA approves Cinvanti for prevention of nausea and vomiting associated with chemotherapy - Heron Therapeutics.

Heron Therapeutics, Inc.has announced that the FDA has approved Cinvanti (aprepitant) injectable emulsion, for intravenous infusion. Cinvanti is a substance...

Added 9 days ago Drug news

Intellis platform for spinal cord stimulation and peripheral nerve stimulation receives CE Mark- Medtronic.

Medtronic plc announced that it received CE (Conformité Européenne) Mark for the Intellis platform for both Spinal Cord Stimulation (SCS)...

Added 21 days ago Drug news

FDA approves Varubi i.v .for the prevention of delayed nausea/ vomiting associated with emetogenic cancer chemotherapy. Tesaro.

OPKO Health, Inc. announces that its licensee, Tesaro Inc. received FDA approval for Varubi (rolapitant) i.v. in combination with other...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

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Psoriasis

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Guidelines

Management of toxicities from immunotherapy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Immunotherapy is an essential component of cancer care and expands the treatment possibilities for patients. Immune checkpoint inhibitors are among the most promising drugs but are associated with toxicities.

Added 1 month ago

Management of infusion reactions to systemic anticancer therapy: ESMO Clinical Practice Guidelines

Most anticancer treatments carry a risk for infusion reactions which incidence may increase when different agents are administered concomitantly.

Added 1 month ago

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 8 months ago

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Journal articles

Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations.

Knowledge of the involvement of the neurokinin substance P in emesis has led to the development of the neurokinin-1 receptor antagonists (NK-1 RAs) for control of chemotherapy-induced nausea and vomiting (CINV)...

Added 9 days ago

Rolapitant: A Review in Chemotherapy-Induced Nausea and Vomiting.

Oral rolapitant (Varubi™; Varuby®), a long-acting neurokinin-1 (NK1) receptor antagonist (RA), is indicated in the USA and EU as part of an antiemetic regimen to prevent delayed chemotherapy-induced nausea and vomiting (CINV)...

Added 9 days ago

Clinical pharmacology of neurokinin-1 receptor antagonists for the treatment of nausea and vomiting associated with chemotherapy.

Introduction: Five NK-1 RA formulations are commercially available to treat the delayed phase of chemotherapy-induced nausea and vomiting (CINV) occurring between days 2–5 post chemotherapy...

Added 1 month ago

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Clinical trials

Melatonin Oral Gel for Oral Mucositis in Patients With Head and Neck Cancer Undergoing Chemoradiation (MUCOMEL)

The main purpose of this study is to assess the efficacy of melatonin oral gel compared to placebo in the...

Added 3 years ago

Early Palliative Care in Metastatic Lung Cancer in Northern France (IMPAQ)

Single-center, prospective, controlled, open-label, randomized, two parallel arms comparing early Palliative care versus Standard care in patients with non-small-cell metastatic...

Added 3 years ago

PROject - Supportive and Palliative Care and INnOvation - Antwerp (Pro-Spinoza) (pro-Spinoza)

It is important to provide high quality palliative care to all patients with a non-curable and life-limiting condition. The Care...

Added 4 years ago

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Blog Posts

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Association of adherence to lifestyle recommendations and risk of colorectal cancer: a prospective Danish cohort study

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Depression in adults with a chronic health problem: putting NICE guidelines into practice

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Palliative care in patients with heart failure

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BMJ Learning - British Medical Learning
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