Latest news articles
Added 2 days ago Drug news
Update on phase III study P301 of SPN 810 explains variability of Impulsive aggression control in ADHD.- Supernus Pharma
Supernus Pharmaceuticals has provided an update on the results from the first Phase III study (P301) of SPN-810, a novel...
Added 2 days ago Drug news
EU approves extension of approval of Kalydeco to infants with CFTR cystic fibrosis.- Vertex Pharma
Vertex Pharmaceuticals announced that the European Commission has granted approval of the label extension for Kalydeco (ivacaftor) to include the...
Added 9 days ago Drug news
Phase III study of Brabafen in Dravet Syndrome published in JAMA Neurology.- Zogenix
Using Brabafen (fenfluramine) from Zogenix in an antiseizure medication regimen that includes the anticonvulsant stiripentol significantly reduces seizures in Dravet...
Learning Zones
An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.
EPNS 2019 Congress Highlights
The epgonline.org team is creating daily reports from the 13th European Paediatric Neurology Society (EPNS) Congress, held in Athens, Greece from 17th to 21st September 2019, to bring you coverage of cutting-edge science and advances in clinical care across all fields of paediatric neurology.
Nephropathic Cystinosis
Learn about the use of cystine-depleting pharmacotherapy and other supportive care measures for patients with nephropathic cystinosis.
+ 2 more
Chronic Lymphocytic Leukaemia (CLL)
Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more
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Transplantation
See information on best practice in solid organ transplantation, and expert discussions on related hot topics.
Atopic Dermatitis
The Atopic Dermatitis Knowledge Centre is an educational resource, intended for healthcare professionals, that provides credible medical information on the epidemiology, pathophysiology and burden of atopic dermatitis, as well as diagnostic techniques, treatment regimens and guideline recommendations.
Anticoagulation Therapy for Stroke Prevention
Anticoagulation therapy for Stroke Prevention Learning Zone offers a deep-dive into atrial fibrillation causes, consequences, diagnosis and management to help you deliver optimal care and prevent strokes in patients living with this common arrhythmia.
Psoriasis Academy
Learn about the burden of psoriasis, unmet needs, the tools used to assess severity and treatment response, what we know about the pathophysiology behind the condition and what the current guidelines say.
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Guidelines
Cannabis-based medicinal products
This guideline covers prescribing of cannabis-based medicinal products for people with intractable nausea and vomiting, chronic pain, spasticity and severe treatment-resistant epilepsy.
Added 8 days ago
Fever in under 5s: assessment and initial management
This guideline covers the assessment and early management of fever with no obvious cause in children aged under 5. It aims to improve clinical assessment and help healthcare professionals diagnose serious illness among young children...
Added 6 years ago
Epilepsies: diagnosis and management
The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.
Added 7 years ago
Journal articles
Efficacy and tolerability of a pasteurised human fibrinogen concentrate in patients with congenital fibrinogen deficiency.
The efficacy and tolerability of a pasteurised human fibrinogen concentrate were assessed in an open, multi-centre, non-controlled retrospective study in patients with congenital fibrinogen deficiency.
Added 45 minutes ago
Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: a randomized pilot trial.
Objectives: Acute acquired hypofibrinogenemia in children undergoing cardiac surgery is a major concern because it often results in perioperative bleeding and high rates of allogeneic blood transfusion.
Added 23 hours ago
Fibrinogen replacement therapy for congenital fibrinogen deficiency.
This review of published studies was conducted to derive data on patients with congenital fibrinogen deficiency (CFD), including dosing of fibrinogen replacement therapy, outcome, and adverse events, either temporally related...
Added 3 days ago
Clinical trials
Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy
The primary objective of the study is to examine the clinical efficacy of nusinersen administered intrathecally at higher doses to participants with spinal muscular atrophy (SMA).
Added 2 months ago
A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis
This 2-year study will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) effects of ocrelizumab in children and adolescents ages >/= 10 to < 18 years with relapsing-remitting multiple sclerosis (RRMS).
Added 2 months ago
A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis (SMR3372)
Randomized, double blind, placebo controlled study. The study has two parts:
Dose-finding part, followed by longer term follow-up (6 months)
Added 1 month ago
Blog Posts
Heather Lander, PhD
Zika Virus: old lessons from a newly emerging pathogen
Posted 3 years ago
Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.
Am Ang Zhang
Autism: Challenges and Obstacles!
Posted 3 years ago
Retired child psychiatrist Am Ang Zhang discusses his experiences of working with the families of autistic children.
Am Ang Zhang
Autism: Frances Tustin and Entrenchment!
Posted 3 years ago
Am Ang Zhang discusses his work with pioneering child psychotherapist Frances Tustin, and his observations of entrenchment in autistic children.
CME
Management of nocturnal enuresis
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BMJ Learning - British Medical Learning
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Idiopathic constipation and nocturnal enuresis in childhood: a guide to management: putting NICE guidelines into practice
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BMJ Learning - British Medical Learning
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Eczema in children: management and advice for parents
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MIMS Learning - Monthly Index of Medical Specialities
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