Added 28 days ago Drug news

FDA approves Midayis (mixed salts of a single-entity amphetamine product) a once daily treatment for ADHD.- Shire plc.

Shire plc has announced that the FDA has approved Midayis (mixed salts of a single-entity amphetamine product), a once-daily treatment...

Added 1 month ago Drug news

FDA approves Cotempla XR-ODT, (methylphenidate extended-release orally disintegrating tablet) to treat ADHD.- Neos Therapeutics

Neos Therapeutics, Inc. has announced that the FDA approved Cotempla XR-ODT, the first and only methylphenidate extended-release orally disintegrating tablet...

Added 1 month ago Advocacy news

19th June marks World Sickle Cell Awareness Day

Guidelines on Paediatric Urology

A collaborative working group consisting of members representing the European Society for Paediatric Urology (ESPU) and the European Association of...

Added 1 year ago

Intravenous fluid therapy in children and young people in hospital

This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing...

Added 1 year ago

Children’s attachment: attachment in children and young people who are adopted from care, in care or at high risk of going into care

This guideline covers the identification, assessment and treatment of attachment difficulties in children and young people up to age 18...

Added 1 year ago

Cerliponase Alfa: First Global Approval.

Cerliponase alfa (Brineura™) is a recombinant human tripeptidyl peptidase-1 (TPP1) being developed by BioMarin Pharmaceutical Inc. for use in patients with neuronal ceroid lipofuscinosis type 2 (CLN2)...

Added 21 days ago

Definitions of quality of life: what has happened and how to move on.

Quality of life (QOL) is an important outcome in spinal cord injury (SCI) rehabilitation, but it is unclear how to define and measure it.

Added 1 month ago

Enuresis: practical guidelines for primary care

Worldwide, around 10% of 6–7-year-olds suffer from enuresis. Enuresis is therefore highly prevalent, but its impact is often underestimated.

Added 1 month ago

Bioavailability and Pharmacokinetics of Intranasal Dexmedetomidine in Children

We aim to characterize the bioavailability and pharmacokinetics of dexmedetomidine after intranasal dosing employing pharmacometric methods in otherwise healthy 1 month to 11 years of age children scheduled...

Added 4 months ago

Setmelanotide for the treatment of early-onset POMC deficiency obesity

The purpose of the study is to determine the effect of setmelanotide (RM-493) on weight and other factors in patients with pro-opiomelanocortin (POMC) deficiency obesity due to rare bi-allelic loss-of function POMC or PCSK1 genetic mutations.

Added 9 months ago

Single Dose Study to Evaluate Safety, Tolerability and Pharmacokinetics of LCZ696 Followed by a 52-week Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure

This study consist of two parts (Part 1 and Part 2). The purpose of Part 1 is to evaluate the...

Added 2 years ago