Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 1 day ago Drug news

CHMP recommends Cyltezo (adalimumab biosimilar) to treat multiple chronic inflammatory diseases based on clinical equivalence to Humira (adalimumab), the reference product.- Boehringer.

Boehringer Ingelheim announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has...

Added 2 days ago Drug news

FDA approval for Adzenys ER (amphetamine) Extended-Release Oral Suspension to treat ADHD.- Neos Therapeutics.

Neos Therapeutics, Inc. announced that the FDA has approved Adzenys ER (amphetamine) Extended-Release Oral Suspension. Neos Therapeutics is the only...

Added 2 days ago Drug news

CHMP recommends approval of marketing extension for Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate) in adolescents with HIV.- Gilead Sciences.

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion recommending a change to the terms of...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Allergic Rhinitis

Allergic rhinitis causes great strain on the workforce. Help to reduce sick days and improve productivity with appropriate treatment options.

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Cystic Fibrosis

View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.

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Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Guidelines

Guidelines on Paediatric Urology

A collaborative working group consisting of members representing the European Society for Paediatric Urology (ESPU) and the European Association of...

Added 1 year ago

Intravenous fluid therapy in children and young people in hospital

This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing...

Added 1 year ago

Children’s attachment: attachment in children and young people who are adopted from care, in care or at high risk of going into care

This guideline covers the identification, assessment and treatment of attachment difficulties in children and young people up to age 18...

Added 1 year ago

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Journal articles

The Desmopressin test in the differential diagnosis between Cushing’s Disease and pseudo-Cushing states

Differentiating Cushing's disease (CD) from pseudo-Cushing (PC) states may still be difficult in current practice.

Added 5 days ago

Comparison of the dexamethasone-suppressed corticotropin-releasing hormone test and low-dose dexamethasone suppression test in the diagnosis of Cushing’s syndrome

The low-dose dexamethasone suppression test (LDDST) is widely used in confirming a diagnosis of Cushing's syndrome. 

Added 5 days ago

The Metyrapone and Dexamethasone Suppression Tests for the Differential Diagnosis of the Adrenocorticotropin-dependent Cushing Syndrome: A Comparison

To develop criteria for interpreting results of the metyrapone test for the differential diagnosis of the adrenocorticotropin (ACTH)-dependent Cushing syndrome.

Added 5 days ago

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Clinical trials

Bioavailability and Pharmacokinetics of Intranasal Dexmedetomidine in Children

We aim to characterize the bioavailability and pharmacokinetics of dexmedetomidine after intranasal dosing employing pharmacometric methods in otherwise healthy 1 month to 11 years of age children scheduled...

Added 6 months ago

Setmelanotide for the treatment of early-onset POMC deficiency obesity

The purpose of the study is to determine the effect of setmelanotide (RM-493) on weight and other factors in patients with pro-opiomelanocortin (POMC) deficiency obesity due to rare bi-allelic loss-of function POMC or PCSK1 genetic mutations.

Added 11 months ago

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Blog Posts

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 1 year ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

Am Ang Zhang

Autism: Challenges and Obstacles!

Posted 1 year ago

Retired child psychiatrist Am Ang Zhang discusses his experiences of working with the families of autistic children.

Am Ang Zhang

Autism: Frances Tustin and Entrenchment!

Posted 1 year ago

Am Ang Zhang discusses his work with pioneering child psychotherapist Frances Tustin, and his observations of entrenchment in autistic children.

CME

The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test

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Management of nocturnal enuresis

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Idiopathic constipation and nocturnal enuresis in childhood: a guide to management: putting NICE guidelines into practice

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