Added 12 hours ago Drug news

FDA approves Kalydeco to treat cystic fibrosis in children aged 12 to <24 months.- Vertex Pharma.

Vertex Pharmaceuticals Incorporated announced the FDA approved Kalydeco (ivacaftor) to include use in children with cystic fibrosis (CF) ages 12...

Added 12 hours ago Drug news

FDA approves Jornay PM to treat ADHD symptoms.- Ironshore Pharma & Development Inc.

Ironshore Pharmaceuticals & Development, Inc. a wholly owned subsidiary of Highland Therapeutics Inc. has announced that the FDA has approved...

Added 8 days ago Drug news

FDA approves Orkambi to include use in children ages 2 through 5 years with cystic fibrosis who have two copies of the F508del-CFTR mutation.- Vertex Pharma.

Vertex Pharmaceuticals Incorporated announced the FDA has approved Orkambi (lumacaftor/ivacaftor) to include use in children ages 2 through 5 years...

Lyme disease

This guideline covers diagnosing and managing Lyme disease. It aims to raise awareness of when Lyme disease should be suspected and ensure that people have prompt and consistent diagnosis and treatment.

Added 2 months ago

Epilepsies: diagnosis and management

The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.

Added 6 years ago

Otitis media (acute): antimicrobial prescribing

This guideline sets out an antimicrobial prescribing strategy for acute otitis media (ear infection). It aims to limit antibiotic use and reduce antimicrobial resistance.

Added 2 months ago

Olopatadine hydrochloride ophthalmic solution for the treatment of allergic conjunctivitis.

This article was created from a comprehensive literature search with information taken from meta-analyses, systematic reviews, and clinical trials of children and adults.

Added 14 days ago

Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.

We investigated the efficacy and safety of cannabidiol added to a regimen of conventional antiepileptic medication to treat drop seizures in patients with the Lennox-Gastaut syndrome...

Added 27 days ago

Nusinersen: A Treatment for Spinal Muscular Atrophy.

Objective: To review the efficacy and safety of nusinersen (Spinraza) in the treatment of spinal muscular atrophy (SMA).

Added 27 days ago

Efficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A Participants (HAVEN 5)

This randomized, multicenter, open-label, Phase 3 study is designed to investigate the efficacy, safety, and pharmacokinetics of emicizumab in participants with hemophilia A regardless of factor VIII (FVIII) inhibitor status.

Added 5 months ago

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 Weeks in Participants With Hemophilia A (HAVEN 4)

This multicenter, open-label, non-randomized study will assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of emicizumab administered at a dose of 6 milligrams per kilogram (mg/kg) every 4 weeks...

Added 5 months ago

Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Patients With Influenza at High Risk of Influenza Complications (CAPSTONE 2)

The primary objective of this study is to evaluate the efficacy of a single, oral dose of Baloxavir Marboxil compared with placebo by measuring the time to improvement of influenza symptoms in patients with influenza...

Added 30 days ago