Latest news articles

Added 6 days ago Drug news

NICE does not recommend Perjeta + Herceptin combination to treat HER2-positive early breast cancer. Roche.

The National Institute for Health and Care Excellence (NICE) released draft guidance recommending against NHS use of combination Perjeta and...

Added 7 days ago Drug news

FDA approves Avastin combined with chemo followed by Avastin for Ovarian Cancer.- Genentech/Roche.

Genentech/Roche announced that the FDA has approved Avastin (bevacizumab) in combination with chemotherapy (carboplatin and paclitaxel), followed by Avastin as...

Added 8 days ago Drug news

FDA approves Keytruda to treat cervical cancer.- Merck Inc.,

Merck Inc., has announced that the FDA has approved Keytruda, the company’s anti-PD-1 therapy, for the treatment of patients with...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

+ 1 more

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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ALP Lab Assessment

ALP Lab Assessment

Discover and overview of hypophosphatasia and details required to facilitate the timely and accurate detection of low alkaline phosphatase.

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Guidelines

Antenatal and postnatal mental health: clinical management and service guidance

This guideline covers recognising, assessing and treating mental health problems in women who are planning to have a baby, are pregnant, or have had a baby or been pregnant in the past year.

Added 3 years ago

Heavy menstrual bleeding: assessment and management

This guideline covers assessing and managing heavy menstrual bleeding (menorrhagia).

Added 11 years ago

Guidelines on Chronic Pelvic Pain

This guideline aims to expand the awareness of caregivers in the field of abdominal and pelvic pain and to assist those who treat patients with abdominal and pelvic pain in their daily practice.

Added 2 years ago

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Journal articles

Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells.

Breast cancer can be classified into molecular subtypes. Tumors overexpressing HER2 protein are more aggressive and metastatic; hence, patients have a poor prognosis.

Added 7 days ago

Trastuzumab-induced cardiotoxicity and its risk factors in real-world setting of breast cancer patients.

The aim of this retrospective study was to determine the frequency and timing of trastuzumab cardiotoxicity and its risk factors in real-world setting.

Added 7 days ago

Rucaparib: An emerging parp inhibitor for treatment of recurrent ovarian cancer.

Recently, Poly-ADP-Ribose Polymerase (PARP) inhibitors are one of the most intensively studied group of antiblastic agents for the management of recurrent ovarian cancer.

Added 16 days ago

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Clinical trials

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer (EarLEE-2)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 7 months ago

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer (EarLEE-1)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 7 months ago

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. (OlympiAD)

This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice of capecitabine, vinorelbine or eribulin in...

Added 7 months ago

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Blog Posts

Alex Keen

EBCC 2018 – Roundup of this year's conference

Posted 2 months ago

At the recent European Breast Cancer Conference the best and brightest in breast cancer research and care met to present and discuss the latest breakthroughs. Brief summaries of some of the key abstracts are found here.

Alex Keen

EBCC 2018 – The multidisciplinary approach to breast cancer care

Posted 3 months ago

The focus of this year’s European Breast Cancer Conference is the importance of multidisciplinary working. Explore the origins of multidisciplinary cancer care and the evidence surrounding it. 

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Testosterone treatment, consultation length and IUD fitting: journals update March 2017

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MIMS Learning - Monthly Index of Medical Specialities
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Step by step: diabetes in pregnancy

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BMJ Learning - British Medical Learning
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90

Ascites: an unusual case: in association with Gut

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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60
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