Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 19 hours ago Drug news

Phase III trial of Keytruda (pembrolizumab) fails to meet primary endpoint in head and neck cancer- Merck Inc

Merck Inc announced that the pivotal phase III KEYNOTE-040 trial investigating Keytruda (pembrolizumab), in previously treated patients with recurrent or...

Added 3 days ago Drug news

EU CHMP recommends approval of Lutathera (lutetium (177Lu) oxodotreotide) in gastroenteropancreatic neuroendocrine tumors- Advanced Accelerator Applications

Advanced Accelerator Applications announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA)...

Added 3 days ago Drug news

FDA approves subcutaneous formulation of Benlysta (belimumab) for systemic lupus erythematosus- GlaxoSmithKline

The FDA has approved a new subcutaneous formulation of Benlysta (belimumab), from GlaxoSmithKline, for the treatment of adult patients with...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Breakthrough Cancer Pain Learning Zone

Invitation to watch the online broadcast of the BeCOn OWN event 'Shifting paradigms in BTcP management' on June 16 2017.

Visit Breakthrough Cancer Pain Learning Zone


Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

Visit Hyperammonaemia


 

Guidelines

Guidelines on Chronic Pelvic Pain

This guideline plays an important role in the process of consolidation and improvement of care for patients with abdominal and...

Added 1 year ago

Guidelines on Neuro-Urology

The European Association of Urology (EAU) Neuro-Urology Guidelines aim to provide information for clinical practitioners on the incidence, definitions, diagnosis,...

Added 1 year ago

Spinal injury: assessment and initial management

This guideline covers the assessment and early management of spinal column and spinal cord injury in pre-hospital settings (including ambulance...

Added 1 year ago

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Journal articles

Cerliponase Alfa: First Global Approval.

Cerliponase alfa (Brineura™) is a recombinant human tripeptidyl peptidase-1 (TPP1) being developed by BioMarin Pharmaceutical Inc. for use in patients with neuronal ceroid lipofuscinosis type 2 (CLN2)...

Added 26 days ago

The clinical landscape for SMA in a new therapeutic era.

Despite significant advances in basic research, the treatment of degenerative diseases of the nervous system remains one of the greatest challenges for translational medicine.

Added 26 days ago

Nusinersen: First Global Approval.

Spinal muscular atrophy (SMA) is a rare autosomal recessive disorder characterized by muscle atrophy and weakness resulting from motor neuron degeneration in the spinal cord and brainstem.

Added 26 days ago

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Clinical trials

Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether aFT218 is safe and effective for the treatment of excessive daytime...

Added 2 years ago

Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer

The purpose of this phase 2 trial is to study the activity of pembrolizumab in combination with bevacizumab in patients...

Added 2 years ago

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

To assess the safety and tolerability of rovalpituzumab tesirine in subjects with specific delta-like protein 3-expressing advanced solid tumors.

Added 2 years ago

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Blog Posts

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 1 year ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Bob Bury

Community Mental Health Provision then and now - is all progress positive?

Posted 3 years ago

Bob Bury muses on the state of modern mental healthcare. Instead of asylums, patients are now part of the community. But what of those who fall through the cracks? How can GPs help patients who need emergency mental health care? Can we learn anything from the methods of the past? Are three letter acronyms helpful? Examining the politics and hurdles of the UK's modern Community Mental Health provision, Bob Bury questions what UK healthcare professionals can do better and how things should change.

CME

Chest x ray: an essential guide to interpretation

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Tricyclic antidepressants and headaches: systematic review and meta-analysis

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Breaking bad news: a how to do it guide

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