Latest news articles

Added 1 day ago Drug news

FDA approves Palynziq to reduce blood phenylalanine concentrations in adult patients with phenylketonuria (PKU).- BioMarin.

BioMarin Pharmaceutical Inc. announced that BioMarin received standard approval from the FDA for Palynziq™ (pegvaliase-pqpz) Injection to reduce blood phenylalanine...

Added 2 days ago Drug news

FDA advisory committee does not recommend buprenorphine sublingual spray as a treatment for moderate-to-severe acute pain.- Insys Therapeutics.

Insys Therapeutics, Inc. confirmed that an expert panel convened by the FDA voted not to recommend approval of the company’s...

Added 6 days ago Drug news

Pfizer announces Phase III study of Lyrica for patients with pediatric epilepsy.

Pfizer Inc. announced positive top-line results of a Phase III study examining the use of Lyrica (pregabalin) Oral Solution CV...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Migraine Knowledge Centre

Migraine Knowledge Centre

The Migraine Knowledge Centre features latest research on the prevalence and impact of migraine, the proposed neurological basis of the condition (and how this is being translated into new and exciting drug therapies), as well as current patient care strategies collated from headache organisations worldwide.

Fabry Disease

Fabry Disease

Explore the pathophysiology and treatment options for Fabry disease, a deficiency of the lysosomal enzyme alpha-galactosidase A

Hyperammonaemia

Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Guidelines

Epilepsies: diagnosis and management

The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care.

Added 6 years ago

Neuropathic pain in adults: pharmacological management in non-specialist settings

This guideline covers managing neuropathic pain (nerve pain) with pharmacological treatments (drugs) in adults in non-specialist settings.

Added 4 years ago

2018 ESC Guidelines for the diagnosis and management of syncope

The document aims to be patient-orientated and focused on therapy, and to reduce the risk of recurrence and the life-threatening consequences of syncope recurrence.

Added 8 years ago

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Journal articles

Association between allergic and nonallergic rhinitis and obstructive sleep apnea.

Allergic rhinitis and nonallergic rhinitis (NAR) are common disorders, which have been considered as potential risk factors for obstructive sleep apnea (OSA).

Added 1 day ago

Levetiracetam monotherapy for the treatment of infants with epilepsy.

Purpose: Levetiracetam is a broad-spectrum anti-epileptic drug that is effective against both focal and generalized epilepsies. In this study, we aimed to evaluate the efficacy, tolerability and safety of levetiracetam monotherapy...

Added 1 month ago

A meta-analysis of randomized controlled trials on levetiracetam in the treatment of pediatric patients with epilepsy.

Objective: To evaluate clinical efficacy, safety, and tolerability of levetiracetam as mono- or adjunctive therapy in the treatment of children and adolescents with epilepsy.

Added 1 month ago

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Clinical trials

Efficacy and Safety of Nerve Root Axial Decompression Surgery in The Treatment of Tethered Cord Syndrome

The aim of this study is to compare the effectiveness and safety of clinical outcomes between capsule surgery and conservative treatment in patients with TCS. A study hypothesis is that outcomes will be improved after capsule surgery.

Added 6 months ago

PeproStat as a Topical Agent Used to Stop Bleeding in Patients Undergoing Surgery

The purpose of this study is to test the effectiveness and safety of a new peptide-based coagulant, PeproStat. The study drug will be applied to patients undergoing liver/soft tissue surgery, vascular surgery or spine surgery.

Added 6 months ago

Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether aFT218 is safe and effective for the treatment of excessive daytime...

Added 2 years ago

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Blog Posts

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 2 years ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Bob Bury

Community Mental Health Provision then and now - is all progress positive?

Posted 4 years ago

Bob Bury muses on the state of modern mental healthcare. Instead of asylums, patients are now part of the community. But what of those who fall through the cracks? How can GPs help patients who need emergency mental health care? Can we learn anything from the methods of the past? Are three letter acronyms helpful? Examining the politics and hurdles of the UK's modern Community Mental Health provision, Bob Bury questions what UK healthcare professionals can do better and how things should change.

CME

Chest x ray: an essential guide to interpretation

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Tricyclic antidepressants and headaches: systematic review and meta-analysis

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Breaking bad news: a how to do it guide

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