Latest news articles

Added 4 days ago Drug news

NICE recommends Spinraza for the treatment of spinal muscular atrophy

Biogen Inc.has announced that The National Institute for Health and Care Excellence (NICE) in the United Kingdom has recommended funding...

Added 6 days ago Drug news

FDA issues guidance to help bring interchangeable biosimilars to market

The FDA has completed its guidance on interchangeability of biosimilars, allowing their substitution for reference biologics without prescribers' sign-off. Similar...

Added 9 days ago Drug news

Pooled analysis of data from three phase II/III randomized clinical trials on the use of rescue medications with Zilretta

Flexion Therapeutics, Inc. announced that a pooled analysis of data from three Phase II/III randomized clinical trials on the use...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Fractures (complex): assessment and management

This guideline covers assessing and managing pelvic fractures, open fractures and severe ankle fractures (known as pilon fractures and intra-articular...

Added 3 years ago

EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis

These evidence-based recommendations and related research agenda provide the basis for sensible use of imaging in routine clinical assessment of people with OA.

Added 10 months ago

Update of EULAR recommendations for the treatment of systemic sclerosis

These updated data-derived and consensus-derived recommendations will help rheumatologists to manage patients with SSc in an evidence-based way. These recommendations also give directions for future clinical research in SSc.

Added 10 months ago

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Journal articles

The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.

IL-17A and IL-17F are prominent members of the IL-17 family of cytokines that regulates both innate and adaptive immunity. IL-17A has been implicated in chronic inflammatory and autoimmune diseases, and anti-IL-17A antibodies...

Added 1 month ago

Novel therapies for immune-mediated inflammatory diseases: What can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn's disease and ulcerative colitis?

The past three decades have witnessed remarkable advances in our ability to target specific elements of the immune and inflammatory response, fuelled by advances in both biotechnology and disease knowledge.

Added 1 month ago

Quality of life and work productivity impairment among psoriasis patients: findings from the National Psoriasis Foundation survey data 2003-2011.

Objective: To ascertain impairment in quality of life and work productivity among patients with psoriasis and psoriatic arthritis.

Added 1 month ago

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Clinical trials

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 1 year ago

Study of Cingalâ„¢ for the Relief of Knee Osteoarthritis Compared to Triamcinolone Hexacetonide

This is a multi-center, randomized, double-blind, parallel group, active comparator controlled trial to evaluate the efficacy and safety of a single injection of Cingal for the relief of joint pain in subjects with OA of the knee.

Added 10 months ago

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

UX023-CL205 is a multicenter, open-label, Phase 2 study in children from 1 to 4 years old with XLH to assess the safety, PD, and efficacy of KRN23 administered via subcutaneous (SC) injections every 2 weeks (Q2W) for a total of 160 weeks.

Added 1 year ago

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Blog Posts

Alex Keen

EULAR 2018 – Biosimilars: the future of rheumatology?

Posted 11 months ago

EULAR's Annual European Congress of Rheumatology aims to encourage innovation and collaboration across all aspects of rheumatology, something that is particularly well illustrated by biologics and their more affordable counterpart, biosimilars. Could they unlock the door to accessible, life-changing treatment for millions more?

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Physical impairments in symptomatic femoroacetabular impingement: a systematic review of the evidence

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Breaking bad news: a how to do it guide

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Pressure ulcers: assessment and management

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