Latest news articles

Added 2 days ago Drug news

Phase III trial of PF 4383119 meets all co-primary endpoints in osteoarthritis pain.- Pfizer + Eli Lilly.

Pfizer and Eli Lilly announced that a 16-week Phase III study in patients with osteoarthritis (OA) pain evaluating subcutaneous administration...

Added 3 days ago Drug news

Study shows RGN 259 equal to or better than competition in treating dry eye disease.- RegeneRx Biopharma.

RegeneRx Biopharmaceutical announced that a new study was published comparing RGN 259 (thymosin beta 4) with currently approved prescription products...

Added 7 days ago Drug news

Evenity re-filed (BLA) with FDA for osteoporosis.- Amgen + UCB.

Amgen and UCB announced the resubmission of the Biologics License Application (BLA) to the FDA for Evenity (romosozumab), a monoclonal...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Fractures (complex): assessment and management

This guideline covers assessing and managing pelvic fractures, open fractures and severe ankle fractures (known as pilon fractures and intra-articular...

Added 2 years ago

EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis

These evidence-based recommendations and related research agenda provide the basis for sensible use of imaging in routine clinical assessment of people with OA.

Added 1 month ago

Update of EULAR recommendations for the treatment of systemic sclerosis

These updated data-derived and consensus-derived recommendations will help rheumatologists to manage patients with SSc in an evidence-based way. These recommendations also give directions for future clinical research in SSc.

Added 1 month ago

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Journal articles

Sublingual sufentanil for postoperative pain relief: first clinical experiences.

The sublingual sufentanil tablet system (SSTS) is a novel hand-held patient-controlled analgesia device developed for treatment of moderate-to-severe postoperative pain. Here we present the first results of its clinical use.

Added 2 days ago

Low Doses of Etanercept Can Be Effective to Maintain Remission in Psoriatic Arthritis Patients.

Objectives: We realized a longitudinal open-label study to determine if increasing intervals between etanercept (ETN) administration could be effective in maintaining remission with a stable dose in a patient population affected...

Added 5 days ago

Impact of Intravenous Acetaminophen on Lengths of Stay and Discharge Status after Total Knee Arthroplasty.

Postoperative pain remains difficult to control after total knee arthroplasty (TKA). While various modalities have been used, they have been associated with several side effects.

Added 11 days ago

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Clinical trials

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 8 months ago

Study of Cingalâ„¢ for the Relief of Knee Osteoarthritis Compared to Triamcinolone Hexacetonide

This is a multi-center, randomized, double-blind, parallel group, active comparator controlled trial to evaluate the efficacy and safety of a single injection of Cingal for the relief of joint pain in subjects with OA of the knee.

Added 25 days ago

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

UX023-CL205 is a multicenter, open-label, Phase 2 study in children from 1 to 4 years old with XLH to assess the safety, PD, and efficacy of KRN23 administered via subcutaneous (SC) injections every 2 weeks (Q2W) for a total of 160 weeks.

Added 4 months ago

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Blog Posts

Alex Keen

EULAR 2018 – Biosimilars: the future of rheumatology?

Posted 1 month ago

EULAR's Annual European Congress of Rheumatology aims to encourage innovation and collaboration across all aspects of rheumatology, something that is particularly well illustrated by biologics and their more affordable counterpart, biosimilars. Could they unlock the door to accessible, life-changing treatment for millions more?

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Physical impairments in symptomatic femoroacetabular impingement: a systematic review of the evidence

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Breaking bad news: a how to do it guide

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Pressure ulcers: assessment and management

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