Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 1 hour ago Drug news

Pfizer sues Johnson & Johnson alleging its anticompetitive practices have denied U.S. patients access to biosimilar competitors including Inflectra (infliximab-dyyb).

Pfizer has filed suit in the U.S. District Court for the Eastern District of Pennsylvania against Johnson & Johnson (J&J)....

Added 6 days ago Drug news

CHMP adopts negative opinion for its Type II extension application for Raxone (idebenone) in Duchenne muscular dystrophy .- Santhera Pharmaceuticals

Santhera Pharmaceuticals) announces that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has...

Added 9 days ago Drug news

Phase III ARCH study results with Evenity (romosozumab) for osteoporosis published in The New England Journal Of Medicine.- Amgen/UCB.

Amgen and UCB announced detailed results from the Phase III ARCH study showing that 12 months of Evenity (romosozumab) followed...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part II: analgesics and other drugs used in rheumatology practice

The objective of the guideline is to provide evidence-based recommendations, which do not imply a legal obligation, for clinicians to...

Added 1 year ago

BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding—Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids

The objective of the guideline is to provide evidence-based recommendations, which do not imply a legal obligation, for clinicians when...

Added 1 year ago

Spinal injury: assessment and initial management

This guideline covers the assessment and early management of spinal column and spinal cord injury in pre-hospital settings (including ambulance...

Added 1 year ago

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Journal articles

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis.

Background: Romosozumab is a monoclonal antibody that binds to and inhibits sclerostin, increases bone formation, and decreases bone resorption.

Added 6 days ago

Expert Panel Recommendations for the Identification and Management of Hyperkalemia and Role of Patiromer in Patients with Chronic Kidney Disease and Heart Failure.

Virtual panel meetings were conducted among 7 physicians, all of whom are independent experts, including 3 nephrologists, 2 cardiologists, and 2 emergency medicine physicians (the panel).

Added 7 days ago

Long-Term Effectiveness of Adalimumab in Patients with Rheumatoid Arthritis: An Observational Analysis from the Corrona Rheumatoid Arthritis Registry.

Introduction: Current recommendations for the management of rheumatoid arthritis (RA) focus on a treat-to-target approach with the objective of maximizing long-term health-related quality-of-life in patients with RA.

Added 8 days ago

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Clinical trials

A Study to Evaluate the Efficacy of Somatropin in the Treatment of Patellar Tendinopathy

Patellar tendinopathy is one of the most frequent causes of non-traumatic knee pain and reduced function in patients. Standard treatment...

Added 2 years ago

Comparing Regional Anaesthesia to Systemic Analgesia to Decrease Post-Operative Delirium in Acute Hip Fracture Surgery (RASAPOD)

Post-operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and...

Added 2 years ago

Inhibition of Co-Stimulation in Rheumatoid Arthritis (ICoSRA)

The purpose of this study is to use abatacept as a clinical molecular probe to evaluate the effects of inhibiting...

Added 2 years ago

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Blog Posts

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Physical impairments in symptomatic femoroacetabular impingement: a systematic review of the evidence

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Breaking bad news: a how to do it guide

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Pressure ulcers: assessment and management

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