Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 1 day ago Drug news

Phase III LEAP 1 trial of BC 3781 (lefamulin) meets primary endpoint in community-acquired bacterial pneumonia.- Nabriva Therapeutics.

Nabriva Therapeutics announced positive topline results from the BC 3781 (lefamulin) evaluation against pneumonia (LEAP 1) trial, which evaluated the...

Added 2 days ago Drug news

CHMP recommends approval of marketing extension for Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate) in adolescents with HIV.- Gilead Sciences.

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion recommending a change to the terms of...

Added 4 days ago Drug news

FDA Advisory Committee recommends Shingrix vaccine for the prevention of herpes zoster (shingles) in adults ages 50 and over.- GSK.

GlaxoSmithKline plc announced that the Vaccines and Related Biological Products Advisory Committee (VRBPAC) of the FDA voted unanimously that the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

Guidelines on Urological Infections

Due to the increasing threat of resistant pathogens worldwide, it has become imperative to limit the use of antibiotics, and...

Added 1 year ago

2015 UK national guideline for the management of infection with Chlamydia trachomatis

This guideline offers recommendations on the diagnostic tests, treatment regimens and health promotion principles needed for the effective management of...

Added 1 year ago

Tuberculosis

This guideline covers preventing, identifying and managing latent and active tuberculosis (TB) in children, young people and adults. It aims...

Added 1 year ago

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Journal articles

Glecaprevir plus pibrentasvir for chronic hepatitis C virus genotype 1, 2, 4, 5, or 6 infection in adults with compensated cirrhosis (EXPEDITION-1): a single-arm, open-label, multicentre phase 3 trial.

Background: The once-daily, ribavirin-free, pangenotypic, direct-acting antiviral regimen, glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological response in phase 2 and 3 studies.

Added 5 days ago

Glecaprevir and pibrentasvir for 12 weeks for hepatitis C virus genotype 1 infection and prior direct-acting antiviral treatment.

Although direct-acting antiviral (DAA) therapies for chronic hepatitis C virus (HCV) infection have demonstrated high rates of sustained virologic response, virologic failure may still occur ...

Added 5 days ago

Effectiveness of Palivizumab in High-risk Infants and Children: A Propensity Score Weighted Regression Analysis.

Background: Infants with premature birth ≤35 weeks gestational age, chronic lung disease of prematurity and congenital heart disease are at an increased risk for lower respiratory tract infections and hospitalization...

Added 1 month ago

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Clinical trials

A Dose Ranging Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' GSK1557484A Vaccine in Children 6 to Less Than 36 Months of Age

The purpose of this study is to assess the safety and immunogenicity of different formulations of GSK Biologicals' influenza candidate...

Added 2 years ago

Clinical and Virological Efficacy of Pegylated Interferon Alpha in the Treatment of Rhinovirus Infection in Patients With Primary Hypogammaglobulinemia: Randomized Controlled Trial (Hypogamma Int1)

The study will investigate the efficacy and safety of subcutaneous interferon alpha -2a to eradicate rhinovirus in patients with primary...

Added 2 years ago

Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-Like Particle Vaccine in an Elderly Population

The purpose of this study is to further develop a formulation and dose regimen of the norovirus GI.1/GII.4 bivalent virus-like...

Added 2 years ago

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Blog Posts

Liam Farrell

Bad smells are good

Posted 11 months ago

Delicacy is not a virtue in this job.

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 1 year ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

Alastair Miller

What is Tropical Medicine?

Posted 1 year ago

At first sight this seems a question with an obvious response and not one that requires much debate in this blog. However, the answer may be more complex than it initially appears and may benefit from further exploration.

CME

Measles: diagnosis and management

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Breaking bad news: a how to do it guide

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Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
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Zika virus

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
90
Search all CME for Infectious diseases