Data from multiple sources - Curated by Toby Galbraith - Last updated 27 February 2017

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Added 1 day ago Drug news

CHMP recommends approval of Keytruda (pembrolizumab), for relapsed or refractory classical Hodgkin lymphoma- Merck Inc

Merck Inc announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has...

Added 6 days ago Drug news

RE-CIRCUIT study of Pradaxa (dabigatran etexilate) shows less bleeding and fewer serious events in atrial fibrillation patients- Boehringer

New data from the RE-CIRCUIT study show a better safety profile for Pradaxa (dabigatran etexilate mesylate), from Boehringer, compared to...

Added 7 days ago Drug news

EBBINGHAUS trial evaluating Repatha (evolocumab) shows no adverse affect on cognitive function in treating dyslipidaemia- Amgen

Amgen has announced detailed results from the Repatha (evolocumab) cognitive function trial (EBBINGHAUS) evaluating the impact on cognitive function in...

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An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients

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See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guideline for reversal of antithrombotics in intracranial hemorrhage.

The use of antithrombotic agents, including anticoagulants, antiplatelet agents, and thrombolytics has increased over the last decade and is expected to continue to rise.

Added 19 days ago

Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient. When these recommendations are implemented patient outcomes may be improved.

Added 19 days ago

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.

The aims of severe perioperative bleeding management are three-fold.

Added 19 days ago

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Journal articles

Risk of venous thromboembolism in men receiving testosterone therapy.

To examine the risk of venous thromboembolism (VTE) associated with exposure to testosterone therapy in middle-aged and older men.

Added 9 days ago

Profile of venetoclax and its potential in the context of treatment of relapsed or refractory chronic lymphocytic leukemia.

Over the last few years, dramatic changes have occurred in the treatment of chronic lymphocytic leukemia (CLL).

Added 11 days ago

Venetoclax in patients with previously treated chronic lymphocytic leukemia.

Venetoclax is the first BCL2 inhibitor to enter routine clinical practice. It is an orally bioavailable small molecule that binds BCL2 very specifically.

Added 11 days ago

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Clinical trials

Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoides

This study will evaluate the efficacy, tolerability and safety of the topical application of mechlorethamine (MCH) formulations in patients with stage I or IIA mycosis fungoides (MF).

Added 4 days ago

Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe Sepsis

Ventilated ICU patients frequently have sepsis and the majority have delirium, a form of brain dysfunction that is an independent predictor of increased risk of dying, length of stay, costs, and prolonged cognitive...

Added 12 days ago

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Case Consults: Changing Paradigms in the Age of Biologics

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Treatment Optimisation in Chronic Lymphocytic Leukaemia

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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