Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 1 day ago Drug news

CHMP recommends VeraSeal for use as a sealant during surgical operations in adults,- Instituto Grifols.

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation...

Added 1 day ago Drug news

Phase III MURANO study of Venclexta (venetoclax) plus Rituxan (rituximab) in relapsed or refractory chronic lymphocytic leukaemia meets primary endpoint.- Genentech/Roche.

Genentech/Roche Group announced that the Phase III MURANO study, which evaluated Venclexta (venetoclax) in combination with Rituxan (rituximab) in people...

Added 1 day ago Drug news

The FDA has accepted for review a Biologics License Application (BLA) for a biosimilar candidate (TPI-G-CSF) referencing Neupogen (filgrastim).- Adello Biologics.

Adello Biologics announced that FDA has accepted for review the company’s Biologics License Application (BLA) for a biosimilar candidate (TPI-G-CSF)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

ESMO Consensus Conference on Malignant Lymphoma: General Perspectives and Recommendations for Prognostic Tools in Mature B-cell Lymphomas and Chronic Lymphocytic Leukaemia

In order to complement the already available European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with malignant lymphomas, ESMO organised a consensus conference...

Added 11 months ago

NCCN Clinical Practice Guidelines in Oncology: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia

CLL remains the most prevalent adult lerkemia in Wester countries but is considered rare in regions such as East Asia. CLL/SLL comprises approximately 7% of newly diagnosed cases of NHL.

Added 11 months ago

Newly Diagnosed and Relapsed Follicular Lymphoma: ESMO Clinical Practice Guidelines

Follicular lymphomas are the second most frequent subtype of nodal lymphoid malignancies in Western Europe. The annual incidence of this disease is rare but has increased during recent decades.

Added 11 months ago

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Journal articles

Nonacog beta pegol in previously treated children with hemophilia B: results from an international open-label phase 3 trial.

Background: Nonacog beta pegol is a recombinant glycoPEGylated factor IX with an extended half-life, developed to improve care for patients with hemophilia B.

Added 6 days ago

Pharmacokinetics of a novel extended half-life glycoPEGylated factor IX, nonacog beta pegol (N9-GP) in previously treated patients with haemophilia B: results from two phase 3 clinical trials.

Introduction: Nonacog beta pegol (N9-GP) is a glycoPEGylated recombinant factor IX (FIX) with an extended half-life developed for routine prophylaxis and the prevention and treatment of bleeding episodes ...

Added 6 days ago

Rituximab Improves the Outcome of Patients With Grade 3 Follicular Lymphoma Receiving Anthracycline-Based Therapy.

Background: The combination of rituximab with chemotherapy has improved the outcome of patients with follicular lymphoma (FL). However, data on Grade 3 FL (FL3) and its subtypes are lacking.

Added 6 days ago

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Clinical trials

A Randomized Double-blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation Versus Placebo in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma of the Activated B-Cell Subtype

This randomized phase III trial studies ibrutinib to see how well it works compared to placebo when given before and after stem cell transplant in treating patients with diffuse large B-cell lymphoma...

Added 3 months ago

ASCT After a Rituximab/Ibrutinib/Ara-c Containing iNduction in Generalized Mantle Cell Lymphoma

The primary objective of the the trial is to establish one of three study arms...

Added 11 months ago

Autologous Transplantation After a Rituximab/Ibrutinib/Ara-c Containing iNduction in Generalized Mantle Cell Lymphoma - a Randomized European Mcl Network Trial

The primary objective of the the trial is to establish one of three study arms, as future standard based on the comparison of the investigator...

Added 3 months ago

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Blog Posts

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Treatment Optimisation in Chronic Lymphocytic Leukaemia

Treatment Optimisation in Chronic Lymphocytic Leukaemia
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Fluid management in acutely ill patients

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Autoimmune pancytopenia following combination chemotherapy for chronic lymphocytic leukaemia

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