Data from multiple sources - Curated by Toby Galbraith - Last updated 27 February 2017

Latest news articles

Added 1 day ago Drug news

Oncologic Drugs Advisory Committee recommends Endari (l-glutamine) to treat sickle cell disease.-Emmaus Life Sciences Inc.

Emmaus Life Sciences Inc. announced that the Oncologic Drugs Advisory Committee of the FDA voted 10 to 3 that the...

Added 5 days ago Drug news

Shire PLC ends development of SHP 656 a proposed treatment for hemophilia A.

Xenetic Biosciences Inc.announced that its partner Shire PLC has ended development of SHP 656 for hemophilia A, because the long-acting...

Added 5 days ago Drug news

EU CHMP recommends Blitzima (rituximab biosimilar) to treat NHL, CLL, granulomatosis with polyangiitis and microscopic polyangiitis. - Celltrion

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients

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Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

ESMO Consensus Conference on Malignant Lymphoma: General Perspectives and Recommendations for Prognostic Tools in Mature B-cell Lymphomas and Chronic Lymphocytic Leukaemia

In order to complement the already available European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with malignant lymphomas, ESMO organised a consensus conference...

Added 7 months ago

NCCN Clinical Practice Guidelines in Oncology: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia

CLL remains the most prevalent adult lerkemia in Wester countries but is considered rare in regions such as East Asia. CLL/SLL comprises approximately 7% of newly diagnosed cases of NHL.

Added 7 months ago

Newly Diagnosed and Relapsed Follicular Lymphoma: ESMO Clinical Practice Guidelines

Follicular lymphomas are the second most frequent subtype of nodal lymphoid malignancies in Western Europe. The annual incidence of this disease is rare but has increased during recent decades.

Added 7 months ago

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Journal articles

Clinical potential of SLAMF7 antibodies - focus on elotuzumab in multiple myeloma.

Elotuzumab is one of the first monoclonal antibodies to be approved for the treatment of multiple myeloma. It is a humanized immunoglobulin G kappa (IgGκ) antibody that targets signaling lymphocytic activation...

Added 4 minutes ago

Venetoclax for the treatment of patients with chronic lymphocytic leukemia.

Venetoclax is a potent, selective inhibitor of BCL-2, a key regulator of the intrinsic pathway of apoptosis. In preclinical studies, venetoclax bound to BCL-2 with high affinity and rapidly induced apoptosis...

Added 16 minutes ago

Development of venetoclax for therapy of lymphoid malignancies.

B-cell lymphoma-2 (BCL-2) family dysfunction and impairment of apoptosis are common in most B-cell lymphoid malignancies. Venetoclax (Venclexta formerly ABT-199, GDC-0199) is a highly selective BCL-2 inhibitor...

Added 24 minutes ago

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Clinical trials

ASCT After a Rituximab/Ibrutinib/Ara-c Containing iNduction in Generalized Mantle Cell Lymphoma

The primary objective of the the trial is to establish one of three study arms...

Added 7 months ago

Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

This randomized phase III trial studies ibrutinib to see how well it works compared to placebo when given before and after stem cell transplant

Added 7 months ago

Ticagrelor And PrEconditioning in Patients With coronaRy Artery diSease (TAPER-S)

The aim of this study is to assess the pleiotropic effects of ticagrelor that could represent possible mechanisms for its...

Added 1 year ago

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Blog Posts

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Treatment Optimisation in Chronic Lymphocytic Leukaemia

Treatment Optimisation in Chronic Lymphocytic Leukaemia
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Union of European Medical Specialists (via European Accreditation Council for CME)
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Fluid management in acutely ill patients

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BMJ Learning - British Medical Learning
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Autoimmune pancytopenia following combination chemotherapy for chronic lymphocytic leukaemia

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BMJ Learning - British Medical Learning
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