311 Results

Yoga Improves Balance and Low-Back Pain, but Not Anxiety, in People with Parkinson's Disease.

Individuals with Parkinson's disease (PD) experience postural instability, low-back pain (LBP), and anxiety. These symptoms increase the risk of falls and decrease quality of life. Research shows yoga improves balance and decreases...

Exercise increases caudate dopamine release and ventral striatal activation in Parkinson's disease.

Background: The objective of this study was to examine the effects of aerobic exercise on evoked dopamine release and activity of the ventral striatum using positron emission tomography and functional magnetic resonance imaging...

Investigation of the roles of dysbindin-1 and SATB2 in the progression of Parkinson's disease.

Objective: Parkinson's disease is a neurodegenerative disease that typically results in the loss of dopaminergic neurons, especially in an area of the brain known as the substantia nigra. Here, we investigated the roles of two...

Deep brain stimulation and genetic variability in Parkinson's disease: a review of the literature.

Deep brain stimulation is offered as symptomatic treatment in advanced Parkinson’s disease, depending on a clinical assessment of the individual patient’s risk-benefit profile. Genetics contribute to phenotypic variability in Parkinson...

The genetic architecture of Parkinson's disease.

Parkinson's disease is a complex neurodegenerative disorder for which both rare and common genetic variants contribute to disease risk, onset, and progression. Mutations in more than 20 genes have been associated with the disease...

Pain in Parkinson's disease: new concepts in pathogenesis and treatment.

Purpose of review: In this review, we discuss the most recent evidence on mechanisms underlying pathological nociceptive processing in Parkinson's disease patients, as well as novel treatment strategies.

Towards understanding neural network signatures of motor skill learning in Parkinson's disease and healthy aging.

In the past decade, neurorehabilitation has been shown to be an effective therapeutic supplement for patients with Parkinson’s disease (PD). However, patients still experience severe problems with the consolidation of learned motor skills.

Immunotherapy in Parkinson's disease: Current status and future directions.

Immunotherapeutic approaches for the treatment of Parkinson’s disease (PD) and related synucleinopathies have steadily developed over the last two decades with several iterations currently being tested in clinical trials.

Epilepsy in the Elderly: Treatment and Consideration of Comorbid Diseases.

Epilepsy is the third most common neurological disorder affecting older adults after stroke and dementia, and the incidence of epilepsy is increasing rapidly in this population. A further increase in the incidence and prevalence of epilepsy...

Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment.

Objective: To assess the association between alcohol consumption and dementia and the roles of mild cognitive impairment (MCI) and apolipoprotein E ε4 (APOE E4) genotype in modifying this association.

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