Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 8 days ago Drug news

Phase III EPOCH study evaluating MK 8931 (verubecestat) in people with mild-to-moderate Alzheimer’s disease halted- Merck Inc

Merck Inc announced that it will be stopping protocol 017, also known as the EPOCH study, a Phase II/III study...

Added 14 days ago Drug news

Phase III clinical data of CVT 301 (inhaled levodopa) shows improvement in Parkinsons disease patients- Acorda Therapeutics

Acorda Therapeutics announced Phase III clinical data of CVT 301 (inhaled levodopa), showing a statistically significant improvement in motor function...

Added 15 days ago Drug news

Idalopirdine fails further trials (STARBEAM and STARBRIGHT) as a treatment for Alzheimers disease -Lundbeck + Otuska

Idalopirdine (LuAE 58054),a 5HT6 antagonist being developed by Lundbeck and Otsuka for the symptomatic treatment of patients with mild to...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Epidemiology, pathophysiology, diagnosis/treatment guidelines, recent publication summaries and more

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Prostate Cancer

How can you balance the harmful effects of treatment with control of prostate cancer growth in otherwise healthy patients?

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American Association Of Clinical Endocrinologists And American College Of Endocrinology Comprehensive Clinical Practice Guidelines For Medical Care Of Patients With Obesity

Development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and the American College of Endocrinology...

Added 2 months ago

Multiple Myeloma: ESMO Clinical Practice Guidelines

The ESMO Clinical Practice Guideline in multiple myeloma, which accounts for approximately 10% of all haematological malignancies, covers recommendations for diagnosis; staging and risk assessment...

Added 4 months ago

Care of dying adults in the last days of life

This guideline covers the clinical care of adults (18 years and over) who are dying during the last 2 to...

Added 1 year ago

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Journal articles

Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes

The electrophysiological effect of levosimendan, a novel Ca(2+)-sensitizing positive inotropic agent and vasodilator, was examined on rat mesenteric arterial myocytes using the patch clamp technique.

Added 2 hours ago

Management of advanced or refractory heart failure

Advanced heart failure, also be defined as stage D heart failure, characterized by advanced structural heart disease and marked symptoms of heart failure at rest...

Added 2 hours ago

Chronotropy: the Cinderella of heart failure pathophysiology and management

A hallmark characteristic of chronic HF, associated with either a reduced (HFrEF) or preserved ejection fraction (HFpEF), is a markedly reduced capacity for physical exertion.

Added 3 hours ago

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Blog Posts

Bob Bury

Legalised killing – leave doctors out of it.

Posted 2 years ago

Would you trust a doctor to decide if you are an appropriate subject for assisted dying? I wouldn't, neither should you, and my colleagues who are not fortunate enough to be retired will be crazy if they allow themselves to be dragged into the process. Proponents of legislative change should man up and face the implications of their proposals, without hiding behind the medical profession.

Vincent de Luise

The End of Sight at the End of Life

Posted 1 year ago

I presented this talk, "The End of Sight at the End of Life," on  4/4/2013 at a Harvard University  "Think Tank" on Health and Aging. The two-day conference, held at the Charles Hotel in Cambridge, Massachusetts, brought together prominent scholars from the Harvard School of Public Health as well as global experts in economics, health care policy and longevity, for a fascinating and thought-provoking colloquium on the demographics and consequences of aging in all societies.


Treatment Optimisation in Chronic Lymphocytic Leukaemia

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Union of European Medical Specialists (via European Accreditation Council for CME)
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