Latest news articles

Added 1 day ago Drug news

OG 217SC filed with the FDA for type 2 diabetes

Novo Nordisk announced the submission of two New Drug Applications (NDAs) to the FDA for OG 217SC (oral semaglutide), the...

Added 1 day ago Drug news

Ozempic filed with FDA for risk reduction in MACE

Novo Nordisk has filed a supplemental NDA (sNDA) with the FDA for once-weekly Ozempic (semaglutide) injection 0.5 mg or 1...

Added 8 days ago Drug news

apact study of Abraxane + gemcitabine following surgical resection for pancreatic cancer failed to achieve primary endpoint

The Celgene-sponsored, pivotal, Phase III apact study evaluating the investigational use of Abraxanein combination with gemcitabine following surgical resection (adjuvant...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cushing's Syndrome

Cushing's Syndrome

Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?

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Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction

Treatment with amiodarone is associated with changes in thyroid function tests, but also with thyroid dysfunction (amiodarone-induced hypothyroidism, AIH, and amiodarone-induced thyrotoxicosis, AIT).

Added 9 months ago

Guidelines on Male Hypogonadism

Androgens play a crucial role in the development and maintenance of male reproductive and sexual functions. Low levels of circulating androgens can cause disturbances in male sexual development, resulting in congenital abnormalities...

Added 4 years ago

The Hospital Management of Hypoglycaemia in Adults with Diabetes Mellitus

These guidelines, produced by the Joint British Diabetes Societies - Inpatient Care Group (JBDS-IP), are intended for use by clinicians and service commissioners to advise the treatment and hospital management of hypoglycaemia...

Added 5 years ago

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Journal articles

Active Cushing's Disease is Characterized by Increased Adipose Tissue Macrophage Presence.

Objective: To determine if chronic endogenous GC exposure due to CD is associated with adipose tissue (AT) inflammation in humans.

Added 11 days ago

Effectiveness of medical treatment for Cushing's syndrome: a systematic review and meta-analysis.

Purpose: To systematically review the effectiveness of medical treatment for Cushing's syndrome in clinical practice, regarding cortisol secretion, clinical symptom improvement, and quality of life. To assess the occurrence of...

Added 11 days ago

Advances in the medical treatment of Cushing's syndrome.

Cushing's syndrome is associated with multisystem morbidity and, when suboptimally treated, increased mortality. Medical therapy is an option for patients if surgery is not successful and can be classified into pituitary-directed drugs...

Added 11 days ago

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Clinical trials

A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome (GRACE)

This is a Phase 3, double-blind, placebo-controlled, randomized-withdrawal study to assess the safety and efficacy of relacorilant in patients with endogenous Cushing syndrome and concurrent 1) Type 2 diabetes mellitus/impaired...

Added 11 days ago

A Study to Assess the Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing's Syndrome.

This is a double-blind, randomized, placebo-controlled withdrawal and rescue/restoration study in subjects with endogenous CS previously treated with single-arm, open-label levoketoconazole that will assess efficacy, safety, tolerability, and...

Added 11 days ago

A Three-part Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of Secukinumab Treatment in Juvenile Idiopathic Arthritis Subtypes of Psoriatic and Enthesitis-related Arthritis

This is a double-blind, placebo-controlled, event-driven randomized withdrawal study to investigate the efficacy and safety of secukinumab treatment in the Juvenile Idiopathic Arthritis (JIA)...

Added 2 years ago

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Blog Posts

Lauren McCracken

Transforming Lives Through Technology: Diabetes

Posted 1 year ago

Right now, with a swipe or tap, I can tell you how many calories I’ve consumed, how far I’ve walked and how well I slept last night. However, digital health technology and its analytics have mixed reviews from the general public, some become obsessed wanting to know every macronutrient that goes into their body and others see it as just another gimmick. But what about those with chronic conditions like diabetes?

Robin Hewings

Diabetes Patients Must Be Better Educated About Their Condition

Posted 3 years ago

Not everyone is convinced that education courses help people look after their diabetes. And the GP I was chatting to a couple of months ago was one of them. He wasn’t sure they worked. People didn’t seem that interested and he wasn’t really sure what people would learn anyway.

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Step by step: how to diagnose and manage type 1 diabetes in adults in primary care

Accrediting body
BMJ Learning - British Medical Learning
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1
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1
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90

Clinical pointers: Blood glucose control in type 2 diabetes

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Clinical pointers: recognising and managing acute complications of diabetes in adults

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
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