Data from multiple sources - Curated by Marshall Pearce - Last updated 06 June 2017

Latest news articles

Added 17 hours ago Drug news

Two phase III trials reported in NEJM for Trumenba showing a protective immune response against diverse meningococcal group B (MenB) strains . Pfizer.

Pfizer Inc. announced that detailed results from two pivotal Phase III studies Meningococcal Group B Vaccine) were published in the...

Added 13 days ago Drug news

Opioid crisis: First once-monthly injectable approved

Indivior PLC announced that the FDA has approved Sublocade (buprenorphine extended- release) injection for subcutaneous use (CIII).

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hyperammonaemia

Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

+ 2 more

Breakthrough Cancer Pain Learning Zone

Breakthrough Cancer Pain Learning Zone

Watch video highlights from the BeCOn OWN 2017 event, including expert opinion, patient experience and panel discussions in the Breakthrough Cancer Pain Learning Zone.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 9 months ago

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

The aim of this document is to provide practical, evidence-based guidelines for the diagnosis and treatment of HF. The principal...

Added 1 year ago

Acute coronary syndrome

This guideline provides recommendations for the management of patients with ACS within the first 12 hours and up to hospital discharge.

Added 2 months ago

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Journal articles

Open versus endovascular repair of ruptured abdominal aortic aneurysms: What have we learned after more than 2 decades of ruptured endovascular aneurysm repair?

Background: Ruptured abdominal aortic aneurysm is one of the most difficult clinical problems in surgical practice, with extraordinarily high morbidity and mortality.

Added 1 month ago

Comparison of 3-Factor Versus 4-Factor Prothrombin Complex Concentrate With Regard to Warfarin Reversal, Blood Product Use, and Costs.

Prothrombin complex concentrates (PCCs) are drug products containing varying amounts of vitamin K-dependent coagulation factors II, VII, IX, and X.

Added 1 month ago

Anticoagulation-associated intracranial haemorrhage in the era of reversal agents

In patients taking oral anticoagulants (OACs), the annual rate of intracranial hemorrhage is 0.3% to 0.6%. Of these bleeds, 46% to 86% are intracerebral; 13% to 45% are subdural, and 1% to 8% are subarachnoidal. 

Added 2 months ago

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Clinical trials

Comparing Regional Anaesthesia to Systemic Analgesia to Decrease Post-Operative Delirium in Acute Hip Fracture Surgery (RASAPOD)

Post-operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and...

Added 2 years ago

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event (TRANSITION)

To explore two modalities of treatment initiation (Pre-discharge, and Post-discharge) with LCZ696 in HFrEF patients following stabilization after an ADHF...

Added 2 years ago

ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction (SF-STEMI)

The purpose of this study is to evaluate whether perioperative use of Shenfu Injection could reduce myocardial injury (enzymatic infarct...

Added 2 years ago

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Blog Posts

Laura Quittenden

What is AF or Atrial Fibrillation?

Posted 25 days ago

This week, from the 20th to the 26th November it is Global AF Awareness Week. Here we explore Atrial Fibrillation (also called AF or AFib), the most common heart rhythm disorder that can lead to stroke, blood clots, heart failure and other heart-related complications. Over 1 million people have been diagnosed with AF in the UK alone.  

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Antia Veiga Feijoo

Clinical Features and Treatment Of Acute Asthma Exacerbations

Posted 2 years ago

This post discusses clinical assessment and treatment of patients with acute asthma exacerbations.

CME

Dermatological emergencies in children

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MIMS Learning - Monthly Index of Medical Specialities
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Emergencies in dermatology

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MIMS Learning - Monthly Index of Medical Specialities
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Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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