Latest news articles

Added 1 day ago Drug news

Complete response letter for N 1539 (i.v.meloxicam) for acute post surgical pain.- Recro Pharma.

Recro Pharma, Inc. announced it has received a Complete Response Letter (CRL) from the FDA Office of Drug Evaluation II...

Added 3 days ago Drug news

Phae III LEAP 2 trial success for lefamulin proposed treatment for moderate community-acquired bacterial pneumonia .-Nabriva Therapeutics

- Nabriva Therapeutics plc announced positive topline results from its Lefamulin Evaluation Against Pneumonia (LEAP 2) clinical trial, the second...

Added 8 days ago Drug news

Phase III study of Crysvita meets primary endpoint in X-linked hypophosphatemia.- Ultragenyx Pharma/Kyowa Hakko Kirin.

Ultragenyx Pharmaceutical, Kyowa Hakko Kirin, and Kyowa Kirin International announced that the Phase III study of Crysvita (burosumab) met its...

Search all news articles for Critical care/intensive care
 

 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

+ 2 more

Pain, Agitation and Delirium (PAD) Management

Pain, Agitation and Delirium (PAD) Management

Discover the latest guidance on assessment and management of pain, agitation and delirium for patients requiring sedation.

+ 4 more

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

Load more

 

Guidelines

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

VTE is a condition in which a blood clot (thrombus) forms in a vein. It most commonly occurs in the...

Added 8 years ago

A practical guideline for the haematological management of major haemorrhage

The aim of these updated guidelines is to provide recommendations for the haematological management of major haemorrhage in any clinical situation...

Added 2 years ago

Acute upper gastrointestinal bleeding in over 16s: management

This guideline covers how upper gastrointestinal bleeding can be effectively managed in adults and young people aged 16 years and older.

Added 5 years ago

Search all guidelines for Critical care/intensive care
 

Journal articles

Effects of levosimendan on mortality in patients with septic shock: systematic review with meta-analysis and trial sequential analysis.

Several studies have investigated a survival benefit for levosimendan treatment in patients with septic shock.

Added 11 days ago

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.

Cardiogenic shock (CS) and low cardiac output syndrome (LCOS) as complications of acute myocardial infarction (AMI), heart failure (HF) or cardiac surgery are life-threatening conditions.

Added 11 days ago

The effectiveness of prehospital hypertonic saline for hypotensive trauma patients: a systematic review and meta-analysis

The optimal prehospital fluid for the treatment of hypotension is unknown. Hypertonic fluids may increase circulatory volume and mute the pro-inflammatory response of the body to injury and illness.

Added 24 days ago

Search all journal articles for Critical care/intensive care
 

Clinical trials

Comparison of Propofol and Dexmedetomidine to Treat Hyperactive and Mixed ICU Delirium - the Basel ProDex Randomized Trial

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am...

Added 1 year ago

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Added 1 year ago

Bioavailability of Subcutaneously Given Dexmedetomidine in Healthy Volunteers

The aim of this study is to investigate the pharmacokinetics of subcutaneously administered dexmedetomidine in healthy volunteers. The absolute bioavailability of subcutaneously...

Added 1 year ago

Search all clinical trials for Critical care/intensive care
 

Blog Posts

Alex Keen

ISICEM 2018 – The Sepsis Six and BUFALO

Posted 2 months ago

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

Laura Quittenden

What is AF or Atrial Fibrillation?

Posted 6 months ago

This week, from the 20th to the 26th November it is Global AF Awareness Week. Here we explore Atrial Fibrillation (also called AF or AFib), the most common heart rhythm disorder that can lead to stroke, blood clots, heart failure and other heart-related complications. Over 1 million people have been diagnosed with AF in the UK alone.  

Professor Gerhard Pölzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 10 months ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

CME

Chest x ray: an essential guide to interpretation

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
90

Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
0
Registration required
1
Subscription fee
90

Fluid management in acutely ill patients

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
Search all CME for Critical care/intensive care