Latest news articles

Drug news

EU CHMP recommends Soliris (eculizumab) to include the treatment of refractory generalized myasthenia gravis (gMG) in patients who are anti-acetylcholine receptor (AChR) antibody-positive.-Alexion Pharma

Alexion Pharmaceuticals, Inc. announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA)...

Drug news

FDA approves Symjepi (epinephrine Injection pre-filled single dose syringe) for the emergency treatment of allergic reactions (Type I) including anaphylaxis.-Adamis Pharma

Adamis Pharmaceuticals Corporation announced that the FDA has approved Adamis’ Epinephrine Injection USP, 1:1000 (0.3 mg Pre-filled single dose syringe)...

Congress news

European Society of Hypertension (ESH) annual congress underway in Milan

The 27th European Meeting on Hypertension and Cardiovascular Protection, begins today in Milan.

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Breakthrough Cancer Pain Learning Zone

Invitation to watch the online broadcast of the BeCOn OWN event 'Shifting paradigms in BTcP management' on June 16 2017.

Visit Breakthrough Cancer Pain Learning Zone


Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

Visit Hyperammonaemia


 

Guidelines

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

BTS/ICS Guidelines for the Ventilatory Management of Acute Hypercapnic Respiratory Failure in Adults

The aim of the guideline is to draw attention to the evidence of suboptimal care in AHRF in the UK,...

Care of dying adults in the last days of life

This guideline covers the clinical care of adults (18 years and over) who are dying during the last 2 to...

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Journal articles

Predictors of 30-day mortality in patients admitted to ED for acute heart failure.

Acute heart failure (AHF) is a leading cause of admission in emergency departments (ED).

Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study

In 2007, the Saline versus Albumin Fluid Evaluation-Translation of Research Into Practice Study (SAFE-TRIPS) reported that...

Definitions of quality of life: what has happened and how to move on.

Quality of life (QOL) is an important outcome in spinal cord injury (SCI) rehabilitation, but it is unclear how to define and measure it.

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Clinical trials

Comparison of Propofol and Dexmedetomidine to Treat Hyperactive and Mixed ICU Delirium - the Basel ProDex Randomized Trial

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am...

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Bioavailability of Subcutaneously Given Dexmedetomidine in Healthy Volunteers

The aim of this study is to investigate the pharmacokinetics of subcutaneously administered dexmedetomidine in healthy volunteers. The absolute bioavailability of subcutaneously...

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Blog Posts

Hugh Harvey

Metrics Madness

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Peter English

The advance decision not to attempt cardiopulmonary resuscitation

Decisions to start cardiopulmonary resuscitation (CPR), or to decide in advance to issue a "do not attempt (cardiopulmonary) resuscitation" (DNAR) notice have always been a hot topic in clinical medicine. It may have become even more so since a recent (June 2014) court decision. This post discusses some of the issues and legalities around DNAR decisions.

CME

Chest x ray: an essential guide to interpretation

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
0
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1
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90

Fluid management in acutely ill patients

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
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90
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