Latest news articles

Added 3 days ago Drug news

FDA Allergenic Products Advisory Committee votes to support the use of Palforzia (AR101) for peanut allergy.- Aimmune Therapeutics Inc.

Aimmune Therapeutics, Inc. announced that the Allergenic Products Advisory Committee (APAC) convened by the FDA voted to support the use...

Added 7 days ago Drug news

Ultragenyx and Kyowa Kirin Co., Ltd., announced plans to submit a sBLA to the FDA for Crysvita for the treatment of tumor-induced osteomalacia

Ultragenyx Pharmaceutical Inc.and Kyowa Kirin Co., Ltd., announced plans to submit a supplemental Biologics License Application (sBLA) to the FDA...

Added 28 days ago Drug news

EPOCH 2 Phase III study of HTX 011 in pain control published in Hernia journal

Heron Therapeutics announced that the results from EPOCH 2, a Phase III study of the investigational agent HTX 011 (bupivacaine...

Search all news articles for Critical care/intensive care
 

 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

+ 2 more

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

+ 1 more

Load more

 

Guidelines

Stroke and transient ischaemic attack in over 16s: diagnosis and initial management

This guideline covers interventions in the acute stage of a stroke or transient ischaemic attack (TIA). It offers the best clinical advice on the diagnosis and acute management of stroke and TIA in the 48 hours after onset of symptoms.

Added 1 month ago

Specialist neonatal respiratory care for babies born preterm

This guideline covers specific aspects of respiratory support (for example, oxygen supplementation, assisted ventilation, treatment of some respiratory disorders, and aspects of monitoring) for preterm babies in hospital.

Added 1 month ago

Delirium: prevention, diagnosis and management

This guideline covers diagnosing and treating delirium in people aged 18 and over in hospital and in long-term residential care or a nursing home. It also covers identifying people at risk of developing delirium in these settings and...

Added 1 month ago

Search all guidelines for Critical care/intensive care
 

Journal articles

Reversal of oral anticoagulation in patients with acute intracerebral hemorrhage.

In light of an aging population with increased cardiovascular comorbidity, the use of oral anticoagulation (OAC) is steadily expanding. A variety of pharmacological alternatives to vitamin K antagonists (VKA) have emerged...

Added 13 days ago

Treatment of refractory vasospastic angina complicated by acute pulmonary oedema with levosimendan: a case report.

Case summary: We present a case of recurrent episodes of VA complicated by acute pulmonary oedema and cardiogenic shock despite maximal tolerated therapy (intravenous calcium antagonist and nitrates) that was successfully...

Added 2 months ago

Evaluation of ventriculo-arterial coupling in ST elevation myocardial infarction with left ventricular dysfunction treated with levosimendan.

Background: Acute heart failure (AHF) after ST-segment elevation myocardial infarction (STEMI) is usually treated with inotropic support or vasoactive medications.

Added 2 months ago

Search all journal articles for Critical care/intensive care
 

Clinical trials

Trial of Andexanet in ICH Patients Receiving an Oral FXa Inhibitor

Randomized, controlled clinical trial evaluating the efficacy and safety of andexanet versus usual standard of care in patients with intracranial hemorrhage anticoagulated with a direct oral anticoagulant

Added 3 months ago

Effects of Long-Term Administration of Human Albumin in Subjects With Decompensated Cirrhosis and Ascites (PRECIOSA)

This is a phase 3, multicenter, randomized, controlled, parallel-group, and open-label clinical study to evaluate the efficacy of standard medical treatment (SMT) + Albutein 20% administration versus SMT alone in subjects with...

Added 6 months ago

HEAL STUDY (Hepatic Encephalopathy and Albumin Study) (HEAL)

This 6 week trial will study changes in cognition, HRQOL and inflammation in patients with covert HE after prior overt HE using multiple IV albumin infusions vs. placebo.

Added 6 months ago

Search all clinical trials for Critical care/intensive care
 

Blog Posts

Alex Keen

ISICEM 2018 – The Sepsis Six and BUFALO

Posted 1 year ago

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

Laura Quittenden

What is AF or Atrial Fibrillation?

Posted 1 year ago

This week, from the 20th to the 26th November it is Global AF Awareness Week. Here we explore Atrial Fibrillation (also called AF or AFib), the most common heart rhythm disorder that can lead to stroke, blood clots, heart failure and other heart-related complications. Over 1 million people have been diagnosed with AF in the UK alone.  

Professor Gerhard Pölzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 2 years ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

CME

Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
0
Registration required
1
Subscription fee
90

Fluid management in acutely ill patients

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Ascites: an unusual case: in association with Gut

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
60
Search all CME for Critical care/intensive care