Latest news articles

Added 1 day ago Drug news

Complete response letter for N 1539 (i.v.meloxicam) for acute post surgical pain.- Recro Pharma.

Recro Pharma, Inc. announced it has received a Complete Response Letter (CRL) from the FDA Office of Drug Evaluation II...

Added 2 days ago Drug news

FDA advisory committee does not recommend buprenorphine sublingual spray as a treatment for moderate-to-severe acute pain.- Insys Therapeutics.

Insys Therapeutics, Inc. confirmed that an expert panel convened by the FDA voted not to recommend approval of the company’s...

Added 16 days ago Drug news

Traumakine fails Phase III INTEREST trial for ARDS.- Faron Pharma.

Faron Pharmaceuticals Ltd the clinical stage biopharmaceutical company, announces top line data from its pan-European Phase III INTEREST trial of...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

+ 2 more

Pain, Agitation and Delirium (PAD) Management

Pain, Agitation and Delirium (PAD) Management

Discover the latest guidance on assessment and management of pain, agitation and delirium for patients requiring sedation.

+ 4 more

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.

The aims of severe perioperative bleeding management are three-fold. First, preoperative identification by anamesis and laboratory testing of those patients for whom the perioperative bleeding risk may be increased...

Added 1 year ago

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 1 year ago

Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version

In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and Emergency Medicine), twelve German medical societies published...

Added 1 year ago

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Journal articles

Dexmedetomidine Based Sedation for Post-surgery Critically Ill Adults: A Meta-analysis of Randomized Controlled Trials.

Using dexmedetomidine (Dex) as a sedative agent may benefit the clinical outcomes of post-surgery patients. We reviewed randomized controlled trials to assess whether use of a Dex could improve the outcomes in post-surgery critically ill adults.

Added 3 months ago

Reversal of dabigatran-associated major bleeding with activated prothrombin concentrate: A prospective cohort study.

The reversal of dabigatran-associated major bleeding can now be achieved with the antidote idarucizumab.

Added 5 months ago

Non-technical skills of surgeons and anaesthetists in simulated operating theatre crises.

Background: Deficiencies in non-technical skills (NTS) have been increasingly implicated in avoidable operating theatre errors. Accordingly, this study sought to characterize the impact of surgeon and anaesthetist...

Added 6 months ago

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Clinical trials

Comparison of Propofol and Dexmedetomidine to Treat Hyperactive and Mixed ICU Delirium - the Basel ProDex Randomized Trial

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am...

Added 1 year ago

Bioavailability and Pharmacokinetics of Intranasal Dexmedetomidine in Children

We aim to characterize the bioavailability and pharmacokinetics of dexmedetomidine after intranasal dosing employing pharmacometric methods in otherwise healthy 1 month to 11 years of age children scheduled...

Added 1 year ago

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Added 1 year ago

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Blog Posts

Alex Keen

ISICEM 2018 – The Sepsis Six and BUFALO

Posted 2 months ago

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

Professor Gerhard Pölzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 10 months ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Starting patients on oral anticoagulants in primary care: how to do it

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Managing CSU and its comorbidities: from primary to secondary care

Managing CSU and its comorbidities: from primary to secondary care
Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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FREE

Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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0
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90
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