Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 4 days ago Drug news

FDA approves Supplemental New Drug Application for Spiriva Respimat (tiotropium bromide) in asthma in people age 6 and older- Boehringer

Boehringer announced that the FDA approved Spiriva Respimat (tiotropium bromide) for the long-term, once-daily maintenance treatment of asthma in people...

Added 4 days ago Drug news

FDA approves Siliq (brodalumab) to treat moderate-to-severe plaque psoriasis.-Valeant Pharma Intl.

The FDA has approved Siliq (brodalumab) to treat adults with moderate-to-severe plaque psoriasis. Siliq is administered as an injection. Siliq...

Added 17 days ago Drug news

European Patent Office invalidates Sprycel (dasatinib) composition of matter patent.- BMS

BMS announced that the European Patent Office (EPO) upheld a decision with regard to European Patent No. 1169038 (the '038...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Spontaneous Urticaria (CSU)

Use our patient case studies to discover how experts diagnose and treat chronic spontaneous urticaria

Visit Chronic Spontaneous Urticaria (CSU)

Cystic Fibrosis

View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines

Visit Cystic Fibrosis

Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

Visit Hyperammonaemia

 

Guidelines

Adalimumab for treating moderate to severe hidradenitis suppurativa

Evidence-based recommendations on adalimumab (Humira) for treating active moderate to severe hidradenitis suppurativa in adults whose disease has not responded to conventional systemic therapy.

Added 6 days ago

Guidelines of care for the management of psoriasis and psoriatic arthritis

Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.

Added 8 days ago

Canadian Guidelines for the Management of Plaque Psoriasis 2009

Since the publication of the 2009 Canadian Guidelines for the Management of Plaque Psoriasis, significant advances have been made in determining the role of T cells in inflammatory and autoimmune diseases. 

Added 8 days ago

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Journal articles

Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis.

The response of psoriasis to antibodies targeting the interleukin (IL)-23/IL-17A pathway suggests a prominent role of T-helper type-17 (Th17) cells in this disease.

Added 4 days ago

A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy and effect of dose reductions

In previous studies, etanercept significantly improved plaque psoriasis and was well tolerated.

Added 4 days ago

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Clinical trials

A Phase 3, Open-Label Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Hidradenitis Suppurativa - PIONEER (Open-Label Extension)

Hidradenitis Suppurativa is a painful, chronic skin disease characterized by recurrent inflamed nodules and abscesses, which may rupture to form fistulas and subsequent scarring.

Added 6 days ago

Safety and Efficacy of Humira (Adalimumab) for Hidradenitis Suppurativa (HS) Peri-Surgically (SHARPS Study) (SHARPS)

The objective of this study is to assess the safety and efficacy of adalimumab prior to surgery in subjects with moderate to severe Hidradenitis Suppurativa (HS) who are surgical candidates.

Added 6 days ago

To Assess the Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Hidradenitis Suppurativa (HIDRI2007)

The trial is a 12-week phase 2 study. Subjects will be given subcutaneous injections at weeks 0 (160mg), 2 (80mg), and then every other week (40mg)

Added 6 days ago

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Blog Posts

Antia Veiga Feijoo

Clinical Features and Treatment Of Acute Asthma Exacerbations

Posted 1 year ago

This post discusses clinical assessment and treatment of patients with acute asthma exacerbations.

Edzard Ernst

But he knows nothing about homeopathy!

Posted 1 year ago

Whenever I criticise their methods, homeopaths claim that my arguments are invalid because I know next to nothing about the subject. Is this because they feel threatened by my arguments? Or could it be that the allegation is incorrect?

You can judge for yourself - here is a (slightly shortened and revised) excerpt from my recent memoire ‘A SCIENTIST IN WONDERLAND’ which recounts my exposure to and experience in homeopathy.

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?