Containing relevant Learning Zones, guidelines, trials and news.
The objective of this document is to guide diagnosis and management of patients with rare coagulation disorders (RCD).
This guideline covers anticoagulants licensed for use in the UK at the time of publication, with the exception of vitamin K antagonists, covered in a separate guideline.
Disseminated intravascular coagulation (DIC) is a reflection of an underlying systemic disorder which affects the coagulation system, simultaneously resulting in pro-coagulant activation, fibrinolytic activation, and consumption coagulopathy....
The objective of this guideline is to provide healthcare professionals with clear guidance on the diagnosis and management of patients with von Willebrand disease.
The pathogenesis of cancer?associated disseminated intravascular coagulation (DIC) is complex and multifactorial. It could present as a spectrum ranging from clinically asymptomatic, but with laboratory markers of coagulation activation...
The objective of this guideline is to provide healthcare professionals with clear, up-to-date, and practical guidance on the management of TTP and related thrombotic microangiopathies, defined by thrombocytopenia, microangiopathic haemolytic...
This is an update of the previous published guideline in 2006. It addresses the problem of thrombocytopenia developing in patients receiving heparin therapy and emphasises the importance of diagnosing heparin induced thrombocytopenia as a serious complication of therapy with a high morbidity and mortality.
This guideline reviews the features of the Antiphospholipid syndrome [APS]- definition, clinical association, pathophysiology and the laboratory detection of Antiphospholipid antibodies.
Maintaining the plasma fibrinogen concentration is important to limit excessive perioperative blood loss. This article considers the evidence for this statement, and questions the justification for using cryoprecipitate rather than...