Data from MHRA (Medicines and Healthcare products Regulatory Agency, UK) - Curated by EPG Health - Last updated 13 July 2018

Indication(s)

- Maxtrex Tablets 2.5 mg:

Methotrexate is a folic acid antagonist and is classified as an antimetabolite cytotoxic agent.

Methotrexate is used in the treatment of adults with severe, active, classical or definite rheumatoid arthritis who are unresponsive or intolerant to conventional therapy.

Methotrexate has also been used in the treatment of severe, uncontrolled psoriasis, which is not responsive to other therapy.

Methotrexate has been used to produce regression in a wide range of neoplastic conditions including acute leukaemias, non-Hodgkin's lymphoma, soft-tissue and osteogenic sarcomas, and solid tumours particularly breast, lung, head and neck, bladder, cervical, ovarian, and testicular carcinoma.


- Maxtrex Tablets 10.0 mg:

Methotrexate is a folic acid antagonist and is classified as an antimetabolite cytotoxic agent.

Methotrexate has been used to produce regression in a wide range of neoplastic conditions including acute leukaemias, non-Hodgkin's lymphoma, soft-tissue and osteogenic sarcomas, and solid tumours particularly breast, lung, head and neck, bladder, cervical, ovarian, and testicular carcinoma.

Methotrexate has also been used in the treatment of severe, uncontrolled psoriasis which is not responsive to other therapy.

Full Prescribing information

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More information

Category Value
Authorisation number 2.5mg: PL 00057/1010 - 10mg: PL 00057/1009
Orphan designation No
Type Prescription only medicine
Marketing authorisation holder Pfizer Limited