Hormone replacement therapy (HRT) for oestrogen deficiency symptoms in women with an intact uterus more than three years after menopause . Prevention of osteoporosis in postmenopausal women at high risk of future fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of osteoporosis. (See also sections 4.4 and 5.1) The experience of treating women older than 65 years is limited.