Hormone Replacement Therapy (HRT) for oestrogen deficiency symptoms in peri- and post-menopausal women. Evorel 50, 75 and 100 only: Prevention of osteoporosis in post-menopausal women at high risk of future fractures who are intolerant of, or contra- indicated for, other medicinal products approved for the prevention of osteoporosis. (See Section 4.4) The experience of treating women older than 65 years is limited.