Adults Diazepam is an anxiolytic, anticonvulsant and central muscle-relaxant. Diazepam is used to relieve anxiety and provide sedation in severe acute anxiety or agitation and for the management of agitation associated with delirium tremens. Diazepam is used to relieve acute muscle spasm and tetanus. Acute convulsions including status epilepticus, also convulsions due to poisoning and febrile convulsions. As an adjunct during endoscopy, in dentistry, surgery, radiology. Cardiac catheterisation, cardioversion, used pre-operatively to relieve anxiety, provide sedation, light anaesthesia and anterograde amnesia. Paediatric patients Diazepam Injection BP is used: • to treat status epilepticus, convulsions due to poisoning, and febrile convulsions; • to treat tetanus; • as a pre-operative medication or premedication. The suitability of treatment with Diazepam Injection BP in this population may need to be assessed on a case-by-case basis – see section 4.2. General Diazepam Injection BP contains propylene glycol and ethanol. This should be taken into consideration when use of a parenteral benzodiazepine is indicated, especially when used in high volumes (e.g. continuous infusion of high doses to treat tetanus or status epilepticus) and/or when used in patients at risk of developing propylene glycol toxicity (see section 4.4).