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The treatment of fungal infections of the skin, scalp, hair, or nails (Tinea barbae, Tinea capitis, Tinea corporis, Tinea cruris, Tinea pedis, Tinea unguium) where topical therapy is considered inappropriate, or the infection has proven refractory to topical therapy. Oral administration of griseofulvin for systemic therapy of fungal infections enables newly formed keratin of the skin, hair, and nails to resist fungal attack. As the new keratin extends, the old infected keratin is shed. Prior to therapy, the type of fungi responsible should be identified. The use of griseofulvin is not justified in the treatment of minor or trivial infections that will respond to topical therapy. Before prescribing Griseofulvin Tablets, consideration should be given to national and/or local guidance on the appropriate use of antifungals.

1. Treatment of infections in which anaerobic bacteria have been identified or are suspected as pathogens, particularly Bacteroides fragilis and other species of Bacteroides and including other species for which metronidazole is bactericidal, such as Fusobacteria , Eubacteria , Clostridia and anaerobic cocci. Flagyl has been used successfully in: septicaemia, bacteraemia, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, peritonitis and post-operative wound infection from which one or more of these anaerobes have been isolated. 2. Prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic Streptococci.

1. Treatment of infections in which anaerobic bacteria have been identified or are suspected as pathogens, particularly Bacteroides fragilis and other species of Bacteroides and including other species for which metronidazole is bactericidal, such as Fusobacteria , Eubacteria , Clostridia and anaerobic cocci. Flagyl has been used successfully in: septicaemia, bacteraemia, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, peritonitis and post-operative wound infection from which one or more of these anaerobes have been isolated. 2. Prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic Streptococci.

Metronidazole tablets are indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected to be the cause. Metronidazole tablets are active against a wide range of pathogenic micro-organisms notably species of Bacteroides, Fusobacteria, Clostridia, Eubacteria, anaerobic cocci and Gardnerella vaginalis . It is also active against Trichomonas, Entamoeba histolytica, Giardia lamblia and Balantidium coli . Metronidazole tablets are indicated in adults and children for the following indications: 1. The prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic streptococci. 2. The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, and post-operative wound infections from which pathogenic anaerobes have been isolated. 3. Urogenital trichomoniasis in the female (trichomonal vaginitis) and in the male. 4. Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or Gardnerella vaginitis). 5. All forms of amoebiasis (intestinal and extra-intestinal disease and that of symptomless cyst passers). 6. Giardiasis. 7. Acute ulcerative gingivitis. 8. Anaerobically-infected leg ulcers and pressure sores. 9. Acute dental infections (e.g. acute pericoronitis and acute apical infections). Considerations should be given to official guidance on the appropriate use of antibacterial agents.

Flagyl is indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected to be the cause. Flagyl is active against a wide range of pathogenic micro-organisms notably species of Bacteroides , Fusobacteria , Clostridia , Eubacteria , anaerobic cocci and Gardnerella vaginalis . It is also active against Trichomonas , Entamoeba histolytica , Giardia lamblia and Balantidium coli . Flagyl is indicated in adults and children for the following indications: • The prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic streptococci • The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, and post-operative wound infections from which pathogenic anaerobes have been isolated • Urogenital trichomoniasis in the female ( Trichomonal vaginitis ) and in the male • Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or Gardnerella vaginitis ) • All forms of amoebiasis (intestinal and extra-intestinal disease and that of symptomless cyst passers) • Giardiasis • Acute ulcerative gingivitis • Anaerobically-infected leg ulcers and pressure sores • Acute dental infections (e.g. acute pericoronitis and acute apical infections) Considerations should be given to official guidance on the appropriate use of antibacterial agents.

Metronidazole tablets are indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected to be the cause. Metronidazole tablets are active against a wide range of pathogenic micro-organisms notably species of Bacteroides, Fusobacteria, Clostridia, Eubacteria, anaerobic cocci and Gardnerella vaginalis . It is also active against Trichomonas, Entamoeba histolytica, Giardia lamblia and Balantidium coli . Metronidazole tablets are indicated in adults and children for the following indications: 1. The prevention of post-operative infections due to anaerobic bacteria, particularly species of Bacteroides and anaerobic streptococci. 2. The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, and post-operative wound infections from which pathogenic anaerobes have been isolated. 3. Urogenital trichomoniasis in the female (trichomonal vaginitis) and in the male. 4. Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or Gardnerella vaginitis). 5. All forms of amoebiasis (intestinal and extra-intestinal disease and that of symptomless cyst passers). 6. Giardiasis. 7. Acute ulcerative gingivitis. 8. Anaerobically-infected leg ulcers and pressure sores. 9. Acute dental infections (e.g. acute pericoronitis and acute apical infections). Considerations should be given to official guidance on the appropriate use of antibacterial agents.

Metronidazole is indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected to be the cause (see sections 4.4 and 5.1). Metronidazole is indicated in adults and children for the following indications: 1) Prevention of post-operative infections due to anaerobic bacteria (gynecological and intra-abdominal operations) 2) Urogenital trichomoniasis in the female and in man. 3) Bacterial vaginosis (also known as non-specific vaginitis) 4) The treatment of septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis and post- operative wound infections from which pathogenic anaerobes have been isolated. 5) All forms of amoebiasis (intestinal and extra-intestinal disease and asymptomatic cyst passers). 6) Acute ulcerative gingivitis. 7) Giardiasis. 8) Acute dental infections (e.g. acute pericoronitis and acute apical infections) 9) Anaerobically-infected leg ulcers and pressure sores 10) Treatment of Helicobacter pylori infection associated with peptic ulcer as part of triple therapy Consideration should be given to official guidance on the appropriate use of antibacterial agents.

Metronidazole Oral Suspension is indicated in the prophylaxis and treatment of infections in which anaerobic bacteria have been identified or are suspected as the pathogen. Metronidazole Oral Suspension is active against a wide range of pathogenic micro-organisms, notably Trichomonas vaginalis , Entamoeba histolytica , Giardia lamblia , Balantidium coli and other species of bacteroides, fusobacteria, eubacteria, clostridia, gardnerella vaginalis and anaerobic cocci. It is indicated in Adults, Children and Newborns with a gestation age of over 40 weeks for: • The treatment of septicaemia, bacteraemia, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis, peritonitis and post-operative wound infections from which one or more pathogenic anaerobes have been isolated. • The prevention of post-operative infections caused by anaerobic bacteria particularly species of bacteroides and anaerobic streptococci. Adults and Children over 10 years only for: • Bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginitis or Gardnerella vaginitis). • Acute dental infections (e.g. acute pericoronitis and acute apical infections). • Anaerobically infected leg ulcers and pressure sores. Adults and Children for: • The treatment of urogenital trichomoniasis in the female (trichomonal vaginitis) and in the male. • All forms of amoebiasis (intestinal and extra-intestinal disease and that of symptomless cyst passers) • Giardiasis • Acute ulcerative gingivitis. Children for • Eradication of Helicobacter pylori Consideration should be given to official guidance on the appropriate use of antibacterial agents.