Data from EMC - Curated by EPG Health - Last updated 20 October 2016
Indication(s)
Used in anaesthesia as a muscle relaxant to facilitate endotracheal intubation, mechanical ventilation and a wide range of surgical and obstetric procedures.
It is also used to reduce the intensity of muscular contractions associated with pharmacologically or electrically-induced convulsions.
Learning Zones
An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.
Pain, Agitation and Delirium (PAD) Management
Discover the latest guidance on assessment and management of pain, agitation and delirium for patients requiring sedation.
+ 4 more
ESICM LIVES Highlights
ESICM LIVES Congress 2018: Bringing you the latest news and insights from the 31st ESICM LIVES Congress, 20–24 October 2018 Paris, France.
Acute and Advanced Heart Failure
What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...
+ 3 more
Oral Anticoagulation Reversal
Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.
Transplantation
See information on best practice in solid organ transplantation, and expert discussions on related hot topics.
Fluid Management
Are you up-to-date with the latest evidence of effective procedures for fluid management?
+ 2 more
CDK 4/6 inhibitors in metastatic breast cancer
The CDK 4/6 Inhibitors in Metastatic Breast Cancer Learning Zone provides insights and information for metastatic breast cancer (mBC) and CDK 4/6 signalling. This includes the burden and pathophysiology of the disease, the role of CDK 4/6 in cell proliferation and an overview of the CDK 4/6 inhibitors that have been approved for the management of mBC.
Cystic Fibrosis Knowledge Centre
View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.
Related Content
Dexmedetomidine Use in ICU Sedation and Postoperative Recovery in Elderly Patients and Post-cardiac Surgery
Added 1 year ago
Use of Dexmedetomidine in Children Undergoing Cardiac Surgery
The aim of the study is to evaluate the efficacy of dexmedetomidine in reducing the need for sedatives and analgesics in the immediate post-operative period in children who underwent surgical correction of...
Added 1 year ago
Acute Neurological ICU Sedation Trial (ANIST)
Dexmedetomidine (Precedex, Hospira) is a "super" selective alpha2-agonist - 8-10x more avid binding to alpha2 receptors than clonidine - and may have particularly favorable characteristics as a continuous i.v...
Added 1 year ago
Incidence of Delirium in Critically Ill Patients in a Dutch University Hospital
The objective of this study is to determine the incidence of delirium in adults patients who are admitted at the critical care unit of a Dutch University Hospital...
Added 1 year ago
Validating a Delirium Prediction Model for Critically Ill Patients
The objective of this study is to determine the incidence of delirium in adults patients who are admitted at the critical care unit of a Dutch University Hospital with the mapping of relevant delirium risk factors...
Added 1 year ago
Dexmedetomidine Based Sedation for Post-surgery Critically Ill Adults: A Meta-analysis of Randomized Controlled Trials.
Using dexmedetomidine (Dex) as a sedative agent may benefit the clinical outcomes of post-surgery patients. We reviewed randomized controlled trials to assess whether use of a Dex could improve the outcomes in post-surgery critically ill adults.
Added 1 year ago
Delirium in postoperative nonventilated intensive care patients: risk factors and outcomes.
Delirium features can vary greatly depending on the postoperative population studied; however, most studies focus only on high-risk patients.
Added 1 year ago
Pharmacologic prevention and treatment of delirium in intensive care patients: a systematic review.
The purpose of the study is to determine if pharmacologic approaches are effective in prevention and treatment of delirium in critically ill patients.
Added 1 year ago
Delirium in critically ill patients.
Delirium is common in critically ill patients and associated with increased length of stay in the intensive care unit (ICU) and long-term cognitive impairment.
Added 1 year ago
Delirium in critically ill patients.
Delirium in the intensive care unit (ICU) is a common diagnosis, with an incidence ranging between 45% and 87%.
Added 1 year ago
Peri-operative management of the surgical patient with diabetes 2015
The purpose of this guideline is to provide detailed guidance on the peri-operative management of the surgical patient with diabetes that is specific to anaesthetists and to ensure that all current national guidance is concordant.
Added 3 years ago
Guidelines for Perioperative Care in Elective Rectal/Pelvic Surgery: Enhanced Recovery After Surgery (ERAS ) Society Recommendations
Background: This review aims to present a consensus for optimal perioperative care in rectal/pelvic surgery, and to provide graded recommendations for items for an evidenced-based enhanced recovery protocol.
Added 6 years ago
Antibiotic prophylaxis in surgery
This guideline provides recommendations based on current evidence for best practice on; the benefits and risks of antibiotic prophylaxis; indications for surgical antibiotic prophylaxis to prevent infection at a range of surgical sites...
Added 10 years ago
AAGBI: Consent for anaesthesia 2017
The following guidelines have been produced in response to the changing ethical and legal background against which anaesthetists, and also intensivists and pain specialists , currently work, while retaining the key principles of...
Added 8 months ago
2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction
Treatment with amiodarone is associated with changes in thyroid function tests, but also with thyroid dysfunction (amiodarone-induced hypothyroidism, AIH, and amiodarone-induced thyrotoxicosis, AIT).
Added 8 months ago
More information
Category | Value |
---|---|
Orphan designation | No |
Type | POM |
Marketing authorisation holder | GlaxoSmithKline UK |