Latest news articles

Added 1 month ago Drug news

Top-line results From phase III study of tanezumab in chronic low back pain. Eli Lilly + Pfizer

Pfizer Inc. and Eli Lilly and Company announced positive top-line results from a Phase III study evaluating tanezumab in patients...

Added 3 months ago Drug news

ABP 710 filed with FDA as biosimilar to Remicade in various indications.- Amgen.

Amgen announced the submission of a Biologics License Application (BLA) to the FDA for ABP 710, a biosimilar candidate to...

Added 4 months ago Drug news

Taltz progress in COAST-V and COAST-W trials for ankylosing spondylitis.- Eli Lilly

Eli Lilly and Company announced that the company will present positive findings from two Phase III studies, COAST-V and COAST-W...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Low back pain and sciatica in over 16s: assessment and management

This guideline covers assessing and managing low back pain and sciatica in people aged 16 and over.

Added 9 years ago

Management of chronic pain

This guideline provides recommendations based on current evidence for best practice in the assessment and management, in non-specialist settings, of adults with chronic non-malignant pain...

Added 5 years ago

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Journal articles

No increased incidence of inflammatory bowel disease among secukinumab-treated patients with moderate to severe psoriasis, psoriatic arthritis, or ankylosing spondylitis: data from 14 phase 2 and phase 3 clinical studies.

Secukinumab (SEC), a fully human anti–interleukin-17A monoclonal antibody, has been evaluated and approved for the treatment of moderate to severe psoriasis (PsO), active psoriatic arthritis (PsA) and active ankylosing spondylitis (AS).

Added 1 year ago

Regulation of peripheral classical and non-classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis.

Objective: To investigate the regulatory effect of tumour necrosis factor (TNF) blockade with infliximab on the distribution of peripheral blood...

Added 3 years ago

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Clinical trials

A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis (COAST-W)

The main purpose of this study is to evaluate the efficacy and safety of ixekizumab in tumor necrosis factor (TNF) inhibitor-experienced participants with radiographic axial spondyloarthritis (rad-axSpA).

Added 8 months ago

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David Warriner

Dr David R Warriner is currently a Cardiology Registrar practising in South Yorkshire. Dr Warriner's clinical and research interests include heart failure, exercise physiology, physiological modelling, sports medicine and medical education. In his free time, Dr Warriner loves reading ... Read more

What is Overdiagnosis?

Overdiagnosis is the diagnosis of disease that will cause neither morbidity nor mortality during a patient’s lifetime. Doctors are trained to listen, examine, test, diagnose and treat patients, but we are not warned of the possible dangers of “diseases”, the diagnosis of which will not benefit the patient and may also lead to harm. I would argue that the Hippocratic oath, in particular “Primum non nocere” (first, do no harm) should be at the forefront of every clinician’s mind when seeing patients.

CME

Diabetes prevention, back pain and PSA testing: clinical update April 2016

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