Latest news articles

Added 1 month ago Drug news

Completion of patient screening in phase III trial of roluperidone to treat negative symptoms in schizophrenia.- Minerva Neurosciences

Minerva Neurosciences, Inc. announced the completion of patient screening in its ongoing Phase III trial with roluperidone to treat negative...

Added 1 month ago Drug news

FDA approves Caplyta to treat schizophrenia. Intra-Cellular Therapies

Intra-Cellular Therapies, Inc. announced that Caplyta (lumateperone) has been approved by the FDA for the treatment of schizophrenia in adults....

Added 2 months ago Drug news

Intra-Cellular Therapies highlights lumateperone presentations at the 58th annual Meeting of the American College of Neuropsychopharmacology.

Intra-Cellular Therapies, Inc. announced data featured during the 58th Annual Meeting of the American College of Neuropsychopharmacology (ACNP) held in...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Optimising anti-TNF treatment using biosimilars

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017

Decisions about the use of psychotropic medication in pregnancy are an ongoing challenge for clinicians and women with mental health problems, owing to the uncertainties around risks of the illness itself to mother and fetus/infant...

Added 2 years ago

Psychosis and schizophrenia in children and young people: Recognition and management

This guideline is concerned with the recognition and management of psychosis and schizophrenia in children and young people up to...

Added 7 years ago

World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia. Part 3: Update 2015 Management of special circumstances: Depression, Suicidality, substance use disorders and pregnancy and lactation

This third part of the updated guidelines covers the management of the following specific treatment circumstances: comorbid depression, suicidality, various comorbid substance use disorders (legal and illegal drugs), and pregnancy and lactation.

Added 4 years ago

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Journal articles

Brexpiprazole: A Review in Schizophrenia.

Brexpiprazole (Rxulti®, Rexulti®) is an oral atypical antipsychotic agent approved for the treatment of schizophrenia in the EU (in adult patients) and the USA, as well as in some other countries, including Japan.

Added 5 months ago

Brexpiprazole for the maintenance treatment of adults with schizophrenia: an evidence-based review and place in therapy.

The purpose of this review is to describe the available data for brexpiprazole in the maintenance treatment of schizophrenia. This objective was completed by searching the databases PubMed, Embase, and ClinicalTrials.gov to...

Added 5 months ago

Comparison of the efficacy and safety of 4 and 2 mg/day brexpiprazole for acute schizophrenia: a meta-analysis of double-blind, randomized placebo-controlled trials.

Purpose: The purpose of this study was to compare the efficacy and safety of brexpiprazole 4 mg/day (B4) and 2 mg/day (B2) for treating acute schizophrenia.

Added 5 months ago

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Clinical trials

Pharmacologic Treatment of Acute Episode of Schizophrenia: a Real World Study

This study attempts to observe the effectiveness and safety of aripiprazole in hospitalized patients with acute schizophrenia episode, and to compare the different drug regimens that may be involved in order to clarify the characteristics...

Added 2 years ago

Study to Evaluate Safety & Efficacy of NaBenĀ® as Add-on Treatment for Schizophrenia in Adults

The proposed Phase IIb/III study is designed to evaluate the safety and efficacy of NaBen® in improving the symptoms of schizophrenia in adults. NaBen® is granted Breakthrough Therapy Designation by US FDA as add-on treatment...

Added 2 years ago

Efficacy and Safety of Adjunctive Pimavanserin for the Treatment of Schizophrenia (ENHANCE-1)

To evaluate the efficacy and safety of adjunctive pimavanserin compared with adjunctive placebo in the treatment of schizophrenia

Added 2 years ago

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Bob Bury

I’m a retired radiologist, and I keep myself busy with hill-walking, fishing and medical journalism/blogging, but mostly I’m a provider of free healthcare for my grandchildren. I am also accredited by the British Humanist Association to officiate at non-religious funerals: http... Read more

Community Mental Health Provision then and now - is all progress positive?

Bob Bury muses on the state of modern mental healthcare. Instead of asylums, patients are now part of the community. But what of those who fall through the cracks? How can GPs help patients who need emergency mental health care? Can we learn anything from the methods of the past? Are three letter acronyms helpful? Examining the politics and hurdles of the UK's modern Community Mental Health provision, Bob Bury questions what UK healthcare professionals can do better and how things should change.

CME

Guidance update: latest NICE guidelines on bipolar disorder, psychosis and schizophrenia in children

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Hallucinations - red flag symptoms

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