Latest news articles

Added 3 months ago Drug news

Pooled data from phase III studies, shows terlipressin was associated with improved overall and transplant-free survival in hepatorenal syndrome type 1 patients.- Mallinckrodt

Mallinckrodt plc , announced results of a pooled analysis of terlipressin clinical trial data in patients with hepatorenal syndrome type...

Added 5 months ago Drug news

ELAD system for acute liver failure fails Phase III trial.- Vital Therapeutics

Vital Therapeutics halted development of its Extracorporeal Liver Assist System (ELAD) for acute forms of liver failure, which failed its...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Cystic Fibrosis Knowledge Centre

Cystic Fibrosis Knowledge Centre

View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.

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Guidelines

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

The following Clinical Practice Guidelines (CPGs) represent the first CPGs on the management of decompensated cirrhosis.

Added 7 months ago

EASL Clinical Practice Guidelines: Management of alcohol-related liver disease

In the following Clinical Practice Guidelines, the latest data on the treatment and management of alcohol-related liver disease will be reviewed and up to date recommendations for clinical management will be provided.

Added 7 months ago

The British Society of Gastroenterology/UKPBC primary biliary cholangitis treatment and management guidelines

Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in...

Added 8 months ago

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Journal articles

Coagulation management during liver transplantation: use of fibrinogen concentrate, recombinant activated Factor VII, prothrombin complex concentrate, and antifibrinolytics

Coagulation management, and transfusion practice in liver transplantation (LT) have been evolving in the recent years due to better understanding of coagulation abnormalities in end-stage liver disease, and clinical management of LT patients

Added 9 months ago

The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.

Background: We previously showed that increased asymmetric dimethylarginine (ADMA) biliary excretion occurs during hepatic ischemia/reperfusion (I/R), prompting us to study the effects of the farnesoid X receptor (FXR)...

Added 11 months ago

The use of obeticholic acid for the management of non-viral liver disease: current clinical practice and future perspectives.

In patients with primary biliary cholangitis, obeticholic acid determines a significant biochemical improvement although the effects on liver fibrosis are lacking.

Added 11 months ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.

CME

Primary biliary cirrhosis

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MIMS Learning - Monthly Index of Medical Specialities
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Abnormal liver function tests: case-based discussion

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MIMS Learning - Monthly Index of Medical Specialities
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Abnormal liver function tests: a guide to interpretation

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MIMS Learning - Monthly Index of Medical Specialities
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1
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90
Search all CME for Other liver diseases