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Added 2 months ago Drug news

European Commission approves Evenity for severe osteoporosis.- Amgen + UCB

Amgen and UCB announced that the European Commission has granted marketing authorization for Evenity (romosozumab) for the treatment of severe...

Added 4 months ago Drug news

Evenity receives positive CHMP opinion for treatment of severe osteoporosis in postmenopausal women at high risk of fracture. Amgen + UCB

Amgen and UCB announced that following a re-examination procedure, the Committee for Medicinal Products for Human Use (CHMP) of the...

Added 4 months ago Drug news

Pfenex receives FDA approval for PF 708, teriparatide injection biosimilar, to treat osteoporosis.

Pfenex Inc. has announced that the FDA has approved the new drug application (“NDA”) for PF 708 submitted under the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Optimising anti-TNF treatment using biosimilars

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

Management of osteoporosis and the prevention of fragility fractures

This guideline provides recommendations based on current evidence for best practice in the management of osteoporosis and prevention of fractures.

Added 4 years ago

Bone health in cancer patients: ESMO Clinical Practice Guidelines

This new ESMO guideline covers areas that make bone health in cancer patients of increasing clinical importance. Besides describing incidence, epidemiology and clinical consequences of bone metastases...

Added 5 years ago

European guidance for the diagnosis and management of osteoporosis in postmenopausal women

Guidance is provided in a European setting on the assessment and treatment of postmenopausal women at risk of fractures due to osteoporosis.

Added 7 years ago

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Journal articles

Low bone mineral density and fractures are highly prevalent in pediatric patients with spinal muscular atrophy regardless of disease severity.

Patients with Spinal Muscular Atrophy (SMA) are at risk for poor bone health. The prevalence of fractures, low areal bone mineral density (aBMD; Z-score ≤−2.0) of the lateral distal femur and of osteoporosis by SMA subtype...

Added 3 months ago

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis.

Background: Romosozumab is a monoclonal antibody that binds to and inhibits sclerostin, increases bone formation, and decreases bone resorption.

Added 2 years ago

Effect of Testosterone Treatment on Volumetric Bone Density and Strength in Older Men With Low Testosterone: A Controlled Clinical Trial

As men age, they experience decreased serum testosterone concentrations, decreased bone mineral density, and increased risk of fracture.

Added 2 years ago

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