Latest news articles

Added 15 days ago Drug news

Phase III EVOLVE-MS-2 study demonstrates improved patient-assessed gastrointestinal tolerability of Vumerity , a treatment for relapsing forms of multiple sclerosis, compared to Tecfidera. - Biogen

Biogen Inc. has announced detailed results from the Phase III EVOLVE-MS-2 study demonstrating the improved patient-assessed gastrointestinal (GI) tolerability of...

Added 21 days ago Drug news

CHMP recommends approval of Mayzent in secondary progressive multiple sclerosis.- Novartis

Novartis announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion...

Added 1 month ago Drug news

EMA PRAC recommends restrictions on use of Lemtrada in multiple sclerosis.- Sanofi

EMA’s safety committee (PRAC) has recommended restrictions on the use of Lemtrada (alemtuzumab), from Sanofi, in patients with relapsing remitting...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

EPNS 2019 Congress Highlights

EPNS 2019 Congress Highlights

The epgonline.org team is creating daily reports from the 13th European Paediatric Neurology Society (EPNS) Congress, held in Athens, Greece from 17th to 21st September 2019, to bring you coverage of cutting-edge science and advances in clinical care across all fields of paediatric neurology. 

Migraine Knowledge Centre

Migraine Knowledge Centre

The Migraine Knowledge Centre features latest research on the prevalence and impact of migraine, the proposed neurological basis of the condition (and how this is being translated into new and exciting drug therapies), as well as current patient care strategies collated from headache organisations worldwide.

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Guidelines

Cannabis-based medicinal products

This guideline covers prescribing of cannabis-based medicinal products for people with intractable nausea and vomiting, chronic pain, spasticity and severe treatment-resistant epilepsy.

Added 2 days ago

Multiple sclerosis in adults: management

This guideline covers diagnosing and managing multiple sclerosis in people aged 18 and over. It aims to improve the quality of life for adults with multiple sclerosis by promoting symptom management...

Added 5 years ago

Association of British Neurologists: revised (2015) guidelines for prescribing disease-modifying treatments in multiple sclerosis

This 2015 revised guideline replaces former versions. It includes all newly approved or licensed treatments for MS and represents a consensus concerning their use.

Added 4 years ago

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Journal articles

Natalizumab promotes activation and pro-inflammatory differentiation of peripheral B cells in multiple sclerosis patients.

Background: In the past, multiple sclerosis (MS) medications have been primarily designed to modulate T cell properties. Based on the emerging concept that B cells are equally important for the propagation of MS, we compared...

Added 12 days ago

Interleukin 18 Polymorphisms and its serum level in Patients with Multiple Sclerosis.

Propose: To determine the serum level of interleukin-18 (IL-18) as well as gene polymorphisms of IL-18 (rs1946518, rs360719, and rs187238).

Added 12 days ago

Long-range connections are more severely damaged and relevant for cognition in multiple sclerosis.

An efficient network such as the human brain features a combination of global integration of information, driven by long-range connections, and local processing involving short-range connections.

Added 12 days ago

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Clinical trials

Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063) (ENLIGHTEN)

This is a multicenter, longitudinal, single-arm, open-label study to describe the change from baseline in cognitive processing speed, measured by the SDMT, in subjects with RMS treated with ozanimod HCl 1 mg at 3 years.

Added 12 days ago

Study to Evaluate Oral BIIB061 Added to Interferon-beta1 (IFN-β1) in Relapsing Multiple Sclerosis (RMS)

The primary objectives of the study are to evaluate the safety of BIIB061 versus placebo in participants with Relapsing Multiple Sclerosis (RMS), and to evaluate the efficacy of BIIB061 to improve disability outcome versus placebo...

Added 2 months ago

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

This 2-year study will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) effects of ocrelizumab in children and adolescents ages >/= 10 to < 18 years with relapsing-remitting multiple sclerosis (RRMS).

Added 2 months ago

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CME

Multiple sclerosis: clinical review

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MIMS Learning - Monthly Index of Medical Specialities
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Search all CME for Multiple sclerosis