Latest news articles

Added 2 months ago Drug news

European Commission approves Spravato nasal spray to treat treatment-resistant major depressive disorder.- Janssen

The Janssen Pharmaceutical Companies of Johnson & Johnson announced that the European Commission (EC) has approved Spravato (esketamine) nasal spray,...

Added 2 months ago Drug news

GEMINI Phase III trial of AXS 05 meets endpoint in major depressive disorder.- Axsome Therapeutics

Axsome Therapeutics announced that AXS 05 (bupropion + dextromethorphan) met the primary endpoint and rapidly and significantly improved symptoms of...

Added 2 months ago Drug news

Intra-Cellular Therapies highlights lumateperone presentations on bipolar depression at the 58th annual meeting of the American College of Neuropsychopharmacology.

Intra-Cellular Therapies, Inc. announced data featured during the 58th Annual Meeting of the American College of Neuropsychopharmacology (ACNP) held in...

Search all news articles for Mood disorders
 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Optimising anti-TNF treatment using biosimilars

Optimising anti-TNF treatment using biosimilars

Biosimilars are uniquely placed to change clinical practice in the fields of gastroenterology, rheumatology, and dermatology. The adoption of biosimilars can improve patient access to the most appropriate treatment, at the optimum time, to ensure the best possible long-term disease outcomes.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

+ 1 more

Load more

Guidelines

Depression in children and young people: identification and management

This guideline covers the identification and treatment of depression in children (5–11 years) and young people (12–18 years) in primary, community and secondary care.

Added 14 years ago

Antenatal and postnatal mental health: clinical management and service guidance

This guideline covers recognising, assessing and treating mental health problems in women who are planning to have a baby, are pregnant, or have had a baby or been pregnant in the past year.

Added 5 years ago

Depression in adults: recognition and management

This guideline covers identifying and managing depression in adults aged 18 years and older, in primary and secondary care.

Added 10 years ago

Search all guidelines for Mood disorders
 

Journal articles

Epidemiology of mental health comorbidity in psoriasis.

Aim: The occurrence of mental health comorbidities such as depression, anxiety, and suicidal ideation or behavior is not uncommon in the context of psoriasis. The negative influence of psoriatic disease on a patient’s...

Added 1 month ago

Esketamine: A Novel Option for Treatment-Resistant Depression.

Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, use requirements, and place in therapy of esketamine for treatment-resistant depression (TRD).

Added 1 month ago

Efficacy and safety of intranasal esketamine for the treatment of major depressive disorder.

Introduction: In March 2019, intranasal esketamine was approved by the Food and Drug Administration (FDA) for the treatment of treatment-resistant depression (TRD) in adults. This review presents the results of clinical trials...

Added 1 month ago

Search all journal articles for Mood disorders
 

Clinical trials

A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Bipolar I Disorder

This study will evaluate the safety and tolerability of brexpiprazole (OPC-34712) in the treatment of subjects with bipolar I disorder. All subjects will receive a starting dose of brexpiprazole which will be titrated up in subsequent visits.

Added 2 years ago

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01)

This study will evaluate the efficacy, safety, and tolerability of rapastinel 450 mg compared to placebo adjunctive to antidepressant therapy (ADT) in patients with major depressive disorder (MDD) who have a partial response to ADT.

Added 2 years ago

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Evaluating the efficacy of vortioxetine 10 mg/day and 20 mg/day versus placebo on depressive symptoms in adolescents (age ≥12 and ≤17 years) with a DSM-5™ [...] diagnosis of Major depressive disorder (MDD).

Added 2 years ago

Search all clinical trials for Mood disorders
 
Bob Bury

I’m a retired radiologist, and I keep myself busy with hill-walking, fishing and medical journalism/blogging, but mostly I’m a provider of free healthcare for my grandchildren. I am also accredited by the British Humanist Association to officiate at non-religious funerals: http... Read more

Community Mental Health Provision then and now - is all progress positive?

Bob Bury muses on the state of modern mental healthcare. Instead of asylums, patients are now part of the community. But what of those who fall through the cracks? How can GPs help patients who need emergency mental health care? Can we learn anything from the methods of the past? Are three letter acronyms helpful? Examining the politics and hurdles of the UK's modern Community Mental Health provision, Bob Bury questions what UK healthcare professionals can do better and how things should change.

CME

Assessing anxiety in palliative care patients

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
1
Registration required
1
Subscription fee
0

Management of depression

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
0
Registration required
1
Subscription fee
0

Depression in adults with a chronic health problem: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
90
Search all CME for Mood disorders