Latest news articles

Added 12 days ago Drug news

European Commission approves Waylivra to treat patients with familial chylomicronemia syndrome at high risk for pancreatitis

Akcea Therapeutics, Inc.,an affiliate of Ionis Pharmaceuticals, Inc., and Ionis Pharmaceuticals, Inc. announced that Waylivra has received conditional marketing authorization...

Added 13 days ago Drug news

Palynziq approved to treat phenylketonuria by European Commission

BioMarin Pharmaceutical Inc announced that the European Commission (EC) has granted marketing authorization for Palynziq (pegvaliase injection) at doses of...

Added 26 days ago Drug news

FDA approves TransPyloric Shuttle device for obesity

BAROnova announced that the FDA has approved the TransPyloric Shuttle (TPS) Device, a non-surgical weight loss solution for adult individuals...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Inflammatory Bowel Disease Knowledge Centre

Inflammatory Bowel Disease Knowledge Centre

The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and unmet needs and the underlying inflammatory processes that drive IBD, considering some of the key inflammatory pathways.

Inflammatory bowel disease assessment tools

Inflammatory bowel disease assessment tools

'New IBD assessment tools at a glance' - an educational symposium sponsored by Sandoz.

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Guidelines

UK Commissioning guide: Massive Weight Loss Body Contouring

This document is about guidance for commissioning reconstructive procedures, post massive weight loss and is based on the best available evidence.

Added 11 months ago

Emergency management of acute hypercalcaemia in adult patients

Abnormalities of parathyroid function, bone resorption, renal calcium reabsorption or dihydroxylation of vitamin D may cause regulatory mechanisms to fail and serum calcium may rise.

Added 6 years ago

Acute Hypocalcaemia - for use in adult patients

Acute hypocalcaemia can be life threatening, necessitating urgent treatment. In severe cases, intravenous calcium forms the mainstay of initial therapy, but it is essential to ascertain the underlying cause and commence specific therapy...

Added 6 years ago

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Journal articles

Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis: The APOLLO Study.

Objective: To evaluate the treatment association of patisiran with regional LV myocardial strain in cardiac manifestation in hATTR amyloidosis.

Added 5 days ago

Obesity, Inflammation, and Prostate Cancer.

The prevalence of obesity is increasing in the world, and obesity-induced disease, insulin-resistance, cardiovascular disease, and malignancies are becoming a problem. Epidemiological studies have shown that obesity is associated...

Added 24 days ago

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial.

Background: There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin, a selective serotonin 2C receptor agonist that suppresses appetite, has been shown to facilitate sustained weight loss in obese or...

Added 1 month ago

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Clinical trials

Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria (PKU)

This study will evaluate SYNB1618 (investigational product) in healthy volunteers (HV) and subjects diagnosed with phenylketonuria (PKU) for the possible treatment of PKU. Phenylketonuria (PKU) is a rare inherited metabolic...

Added 26 days ago

CARAT: Canagliflozin vs. placebo for post bariatric patients with persistent type 2 diabetes

This is a prospective, randomized clinical trial for patients with recurrent type 2 diabetes post-gastric bypass surgery that will compare a 6 month course of canagliflozin monotherapy vs. placebo on clinical outcomes of type 2 diabetes.

Added 2 years ago

Setmelanotide for the treatment of early-onset POMC deficiency obesity

The purpose of the study is to determine the effect of setmelanotide (RM-493) on weight and other factors in patients with pro-opiomelanocortin (POMC) deficiency obesity due to rare bi-allelic loss-of function POMC or PCSK1 genetic mutations.

Added 2 years ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.

CME

Obesity: clinical review

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MIMS Learning - Monthly Index of Medical Specialities
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The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test

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BMJ Learning - British Medical Learning
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Obesity: a guide to prevention and management - putting NICE guidelines into practice

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BMJ Learning - British Medical Learning
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90
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