Latest news articles

Added 10 days ago Drug news

Phase III pivotal trial data for RDZ 5792 for hyperphosphatemia published in Journal of the American Society of Nephrology

Ardelyx announced the publication in the Journal of the American Society of Nephrology (JASN) of results from the first of...

Added 15 days ago Drug news

Conditional approval of Waylivra to treat genetically confirmed familial chylomicronemia syndrome

Akcea Therapeutics, Inc. an affiliate of Ionis Pharmaceuticals, Inc., and Ionis Pharmaceuticals, Inc. announced that the Committee for Medicinal Products...

Added 17 days ago Drug news

Positive results for treatment to reduce blood phenylalanine (Phe) concentrations in patients with phenylketonuria (PKU)

BioMarin Pharmaceutical Inc. announced that the Committee for Medicinal Products for Human Use (CHMP), the scientific committee of the European...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Cystic Fibrosis Knowledge Centre

Cystic Fibrosis Knowledge Centre

View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.

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Guidelines

UK Commissioning guide: Massive Weight Loss Body Contouring

This document is about guidance for commissioning reconstructive procedures, post massive weight loss and is based on the best available evidence.

Added 9 months ago

Emergency management of acute hypercalcaemia in adult patients

Abnormalities of parathyroid function, bone resorption, renal calcium reabsorption or dihydroxylation of vitamin D may cause regulatory mechanisms to fail and serum calcium may rise.

Added 6 years ago

Acute Hypocalcaemia - for use in adult patients

Acute hypocalcaemia can be life threatening, necessitating urgent treatment. In severe cases, intravenous calcium forms the mainstay of initial therapy, but it is essential to ascertain the underlying cause and commence specific therapy...

Added 6 years ago

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Journal articles

Short-Term Outcomes of Inflammatory Bowel Disease after Roux-En-Y Gastric Bypass vs Sleeve Gastrectomy.

Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) are the most effective therapies for obesity and may have beneficial effects on the immune system. Therefore, we compared RYGB versus SG outcomes in the patients with IBD.

Added 18 days ago

Teenagers and young adults with nephropathic cystinosis display significant bone disease and cortical impairment.

Background: Bone impairment appears to be a novel complication of nephropathic cystinosis despite cysteamine therapy. Its exact underlying pathophysiology is nevertheless unclear.

Added 1 month ago

Skeletal Consequences of Nephropathic Cystinosis.

Nephropathic cystinosis is a rare lysosomal storage disorder. Patients present in the first year of life with renal Fanconi syndrome that evolves to progressive chronic kidney disease (CKD).

Added 1 month ago

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Clinical trials

CARAT: Canagliflozin vs. placebo for post bariatric patients with persistent type 2 diabetes

This is a prospective, randomized clinical trial for patients with recurrent type 2 diabetes post-gastric bypass surgery that will compare a 6 month course of canagliflozin monotherapy vs. placebo on clinical outcomes of type 2 diabetes.

Added 2 years ago

Setmelanotide for the treatment of early-onset POMC deficiency obesity

The purpose of the study is to determine the effect of setmelanotide (RM-493) on weight and other factors in patients with pro-opiomelanocortin (POMC) deficiency obesity due to rare bi-allelic loss-of function POMC or PCSK1 genetic mutations.

Added 2 years ago

Division-less gastric bypass, step to decrease cost and early nightmare of bariateric surgery

The purpose of this study is to determine the efficacy of of gastric bypass without gastric division as a treatment for morbid obesity.

Added 2 years ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.

CME

Obesity: clinical review

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The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test

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BMJ Learning - British Medical Learning
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Obesity: a guide to prevention and management - putting NICE guidelines into practice

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BMJ Learning - British Medical Learning
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