Melanomas of skin

Although it is one of the rarer forms of skin cancer, melanoma is responsible for a disproportionate amount of mortality. Its incidence has been increasing over time, and is

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Latest news articles

Added 3 months ago Drug news

EU application withdrawn for Balimek in NRAS-mutant melanoma.

Pierre Fabre Médicament officially notified the Committee for Medicinal Products for Human Use (CHMP) that it wished to withdraw its...

Added 4 months ago Drug news

Phase III trial of Keytruda meets primary endpoint in resected high-risk melanoma.

Successful trial results announced by Merck.

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Communicating Metastatic Breast Cancer Learning Zone

Communicating Metastatic Breast Cancer Learning Zone

This learning zone offers a short overview of the challenges faced by both healthcare professionals and patient when communicating end-stage or metastatic cancer.

Breakthrough Cancer Pain Learning Zone

Breakthrough Cancer Pain Learning Zone

Watch video highlights from the BeCOn OWN 2017 event, including expert opinion, patient experience and panel discussions in the Breakthrough Cancer Pain Learning Zone.

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Guidelines

Cutaneous melanoma

This guideline provides advice at all stages of the patient’s pathway of care, from primary prevention to early recognition, treatment and follow up. It does not address melanomas of non-cutaneous origin...

Added 7 months ago

Cutaneous melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Cutaneous melanoma is the most common type of melanoma, and UV exposure is one of the main risk factors.

Added 2 years ago

Melanoma: assessment and management

This guideline covers the assessment and management of melanoma (a type of skin cancer) in children, young people and adults. It aims to reduce variation in practice and improve survival.

Added 2 years ago

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Journal articles

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.

We sought to determine whether adjuvant dabrafenib plus trametinib would improve outcomes in patients with resected, stage III melanoma with BRAF V600 mutations.

Added 2 months ago

Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib.

Purpose: To report 5-year landmark analysis efficacy and safety outcomes in patients with BRAF V600–mutant metastatic melanoma (MM) who received BRAF inhibitor dabrafenib (D) and MEK inhibitor trametinib (T) combination...

Added 2 months ago

Dabrafenib plus trametinib for compassionate use in metastatic melanoma: A STROBE-compliant retrospective observational postauthorization study.

The main objective of the study was to evaluate the efficacy and safety of dabrafenib alone or combined with trametinib for compassionate use in patients with metastatic melanoma.

Added 2 months ago

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Clinical trials

A Study of the BRAF Inhibitor Dabrafenib in Combination With the MEK Inhibitor Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma After Surgical Resection. (COMBI-AD)

This is a two-arm, randomized, double-blind Phase III study of dabrafenib in combination with trametinib versus two placebos in the adjuvant treatment of melanoma after surgical resection.

Added 6 years ago

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CME

Urgent referrals in dermatology

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Malignant melanoma: clinical review

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Developments in melanoma treatment

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