Data from multiple sources - Curated by Toby Galbraith - Last updated 04 April 2017

Focus on melanomas of skin

Although it is one of the rarer forms of skin cancer, melanoma is responsible for a disproportionate amount of mortality. Its incidence has been increasing over time, and is heavily linked to sun exposure. Figures from the World Health Organization suggest an annual incidence of 132,000 worldwide.

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Latest news articles

Added 2 months ago Drug news

Array BioPharma Inc.,withdraws from the FDA, binimetinib monotherapy for the treatment of NRAS-mutant melanoma.

Array BioPharma Inc. announced that it has withdrawn from the FDA Division of Oncology Products its new drug application (NDA)...

Added 9 months ago Drug news

UK NICE U-turn now recommends Imlygic (talimogene laherparepvec) for unresectable, regionally or distantly metastatic (Stage IIIB, IIIC or IVM1a) melanoma- Amgen

NICE has issued final guidance overturning its earlier recommendation, and now endorsing Imlygic (talimogene laherparepvec), from Amgen, as an option...

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Guidelines

Melanoma: assessment and management

This guideline covers the assessment and management of melanoma (a type of skin cancer) in children, young people and adults....

Added 1 year ago

Cutaneous melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Cutaneous melanoma is the most common type of melanoma, and UV exposure is one of the main risk factors. The...

Added 1 year ago

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Journal articles

Dabrafenib: a new opportunity for the treatment of BRAF V600-positive melanoma.

Prior to 2011, the 1-year survival rates for patients suffering from advanced or metastatic melanoma was as low as 33%, with a median overall survival of about 9 months. Several chemotherapeutic regimens have been applied ...

Added 4 days ago

Pembrolizumab use for the treatment of advanced melanoma.

Introduction: Until recently, overall long term survival in patients with stage IV melanoma was lower than 10 %. However, the treatment of melanoma has evolved rapidly over the last few years ...

Added 1 month ago

Risk of cumulative toxicity after complete melanoma response with pembrolizumab.

Pembrolizumab is an approved first-line systemic therapy for unresectable metastatic melanoma. Despite the achievement of complete and durable responses in a small subgroup of patients, it is standard practice that ...

Added 1 month ago

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CME

Urgent referrals in dermatology

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Malignant melanoma: clinical review

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Developments in melanoma treatment

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