Latest news articles

Added 9 months ago Drug news

European Commission approves Adcetris with AVD chemotherapy for untreated CD30+ stage IV classical Hodgkin lymphoma .- Takeda + Seattle Genetics

Seattle Genetics, Inc announced that its collaborator, Takeda Pharmaceutical Company Limited , received approval from the European Commission to extend...

Added 10 months ago Drug news

Adcetris + chemotherapy results of ECHELON-1 trial for classical Hodgkin lymphoma is published in Clinical Cancer Research.

Seattle Genetics, Inc.announced the publication of data from the ECHELON-1 phase III clinical trial online in the journal Clinical Cancer...

Added 11 months ago Drug news

CHMP recommends extension of approval of Adcetris in CD30+ Stage IV Hodgkin lymphoma.- Takeda.

Takeda Pharmaceutical announced that the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) adopted a positive...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Biosimilars Knowledge Centre

Biosimilars Knowledge Centre

What are biologics and how do they differ from small molecule medicines? Discover more about their development, as well as the manufacturing and regulatory processes in the Biosimilars in Oncology Knowledge Centre.

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Guidelines

Guidelines for the investigation and management of nodular lymphocyte predominant Hodgkin lymphoma

This guideline discusses the investigation and management of patients of all ages with nodular lymphocyte predominant Hodgkin lymphoma...

Added 4 years ago

Guidelines on the management and admission to intensive care of critically ill adult patients with haematological malignancy in the UK

Haem-onc inpatients are at risk of critical illness and should be identified early using NEWS. ICU referral should involve direct discussion between consultant haematologist and consultant intensivist.

Added 4 years ago

Hodgkin’s lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The 2014 update elaborates on two histologically distinguished entities: classical Hodgkin's lymphoma that accounts about 95% of cases and nodular lymphocyte-predominant Hodgkin's lymphoma, which represents the remainder of cases.

Added 5 years ago

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Journal articles

Bone marrow versus peripheral blood as a graft source for haploidentical donor transplantation in adults using post-transplant cyclophosphamide-A systematic review and meta-analysis.

Background: Peripheral-blood (PB) and bone marrow (BM) are both widely used in hematopoietic stem cell transplantation (HSCT). However, it is unclear whether PB or BM produces a more satisfactory outcome in haploidentical HSCT...

Added 8 months ago

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.

An HIV-1-infected adult underwent allo-HSCT for Hodgkin's lymphoma using cells from a CCR5Δ32/Δ32 donor. He experienced mild gut graft versus host disease.

Added 9 months ago

Pembrolizumab and its role in relapsed/refractory classical Hodgkin's lymphoma: evidence to date and clinical utility.

Immune evasion is a critical mechanism of malignant cell survival, and relies in part on molecular signaling through the programmed cell death 1 (PD-1)/PD-1 ligand (PD-L1) axis that contributes to T cell exhaustion.

Added 1 year ago

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Clinical trials

Phase 3 Frontline Therapy Trial in Patients With Advanced Classical Hodgkin Lymphoma

This open-label, randomized, 2-arm, multicenter, phase 3 study has the primary objective of comparing the modified progression-free survival (mPFS) obtained with brentuximab vedotin (ADCETRIS®) plus AVD...

Added 2 years ago

A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma

This is a single-arm, open-label, multicenter, pivotal clinical trial to evaluate the efficacy and safety of brentuximab vedotin (SGN-35) as...

Added 11 years ago

A Dose-Escalating Study of Obinutuzumab in Patients With B-lymphocyte Antigen (CD20+) Malignant Disease (GAUGUIN)

The primary objective for the phase I part of the study is to investigate the safety and tolerability of escalating intravenous (IV) doses of obinutuzumab given as monotherapy...

Added 2 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.