Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 20 days ago Drug news

FDA grants market authorization of ClearL Lab Reagents (T1, T2, B1, B2, M) to Beckman Coulter, Inc.to aid in the detection of leukemias and lymphomas.

The FDA has granted market authorization of ClearLLab Reagents (T1, T2, B1, B2, M) to Beckman Coulter, Inc. The allowed...

Added 24 days ago Drug news

Phase III ECHELON-1 trial of Adcetris (brentuximab vedotin) met primary endpoint in untreated Hodgkin lymphoma- Takeda Pharmaceutical and Seattle Genetics

Takeda Pharmaceutical and Seattle Genetics announced that the Phase III ECHELON-1 clinical trial of Adcetris (brentuximab vedotin) in previously untreated...

Added 1 month ago Drug news

BMS and Seattle Genetics move Adcetris (brentuximab vedotin) and Opdivo (nivolumab) combination into Phase III forclassical Hodgkin lymphoma .

Bristol-Myers Squibb Company (BMS) and Seattle Genetics, Inc. announced that the companies have entered into a collaboration agreement to evaluate...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Airway Disease

The Airway Disease Learning Zone is an area where you can access the information about VisionAir and the upcoming live broadcast. A video presentation will be available from EAACI 2017 entitled 'Personalising Clinical Management in Severe Asthma'. The Inhalation Technology page will feature video presentations from the live broadcast soon. 

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Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Guidelines for the investigation and management of nodular lymphocyte predominant Hodgkin lymphoma

The objective of this guideline is to provide healthcare professionals with guidance on the investigation and management of patients with...

Added 1 year ago

Guidelines on the management and admission to intensive care of critically ill adult patients with haematological malignancy in the UK

This guideline is intended to be of use to haematologists and intensivists practising in the UK, and outlines some of...

Added 1 year ago

Hodgkin's Lymphoma: ESMO Clinical Practice Guidelines

The 2014 update elaborates on two histologically distinguished entities: classical Hodgkin's lymphoma that accounts about 95% of cases and nodular lymphocyte-predominant Hodgkin's lymphoma...

Added 9 months ago

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Journal articles

Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents.

Despite the success of anti-CD20 monoclonal antibody (mAb) in the treatment of lymphoma, there remains considerable uncertainty about their mechanism(s) of action.

Added 1 month ago

Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection.

Rituximab, a monoclonal antibody that targets CD20 on B cells, is now central to the treatment of a variety of malignant and autoimmune disorders.

Added 1 month ago

Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies.

The anti-CD20 mAb rituximab has substantially improved the clinical outcome of patients with a wide range of B-cell malignancies.

Added 1 month ago

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Clinical trials

A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma

This is a single-arm, open-label, multicenter, pivotal clinical trial to evaluate the efficacy and safety of brentuximab vedotin (SGN-35) as...

Added 9 years ago

A Dose-Escalating Study of Obinutuzumab in Patients With B-lymphocyte Antigen (CD20+) Malignant Disease (GAUGUIN)

The primary objective for the phase I part of the study is to investigate the safety and tolerability of escalating intravenous (IV) doses of obinutuzumab given as monotherapy...

Added 3 months ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.