Latest news articles

Added 22 days ago Drug news

CHMP recommends approval of Duzallo for hyperuricaemia in gout.- Gruenenthal.

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation...

Added 1 month ago Drug news

JAMA article shows dramatic increase in emergency department visits by gout patients.- Horizon Pharma.

Results from a new study presented in an oral presentation at the Annual European Congress of Rheumatology (EULAR 2018) show...

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An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

IL-17A in Psoriasis

IL-17A in Psoriasis

Experts discuss new targeted therapies for psoriasis at the European Association of Dermatology and Venereology (EADV) Congress.

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Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

The British Society for Rheumatology Guideline for the Management of Gout

This guideline aims to offer revised and updated, concise, patient-focused, evidence-based, expert recommendations for the management of gout in the UK.

Added 4 months ago

2016 updated EULAR evidence-based recommendations for the management of gout

These recommendations aim to inform physicians and patients about the non-pharmacological and pharmacological treatments for gout and to provide the best strategies to achieve the predefined urate target to cure the disease.

Added 1 month ago

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Journal articles

Chronic Disease Approaches Needed to Curb Gout’s Growing Burden.

Gout’s bad rap as disease of dietary excess has sometimes obscured the complex, chronic nature of the disease and led to ineffective care for many patients.

Added 23 days ago

Lesinurad: A Review in Hyperuricaemia of Gout.

Lesinurad (Zurampic®) is an oral selective inhibitor of the URAT1 and OAT4 uric acid (UA) transporters of the kidney, via which it inhibits UA reabsorption and thus increases renal UA excretion and lowers serum UA (sUA) levels.

Added 1 year ago

Lesinurad: A significant advancement or just another addition to existing therapies of gout?

Gout is a metabolic disorder that usually presents as recurrent episodes of acute arthritis due to deposition of crystals in joints and cartilages. Despite the availability of several drugs for gout, its management is still less than adequate.

Added 1 year ago

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Clinical trials

Combining Lesinurad With Allopurinol in Inadequate Responders (CLEAR 1)

This study that compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who have had an inadequate response to allopurinol.

Added 7 years ago

Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat (CRYSTAL)

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with febuxostat...

Added 7 years ago

Combining Lesinurad With Allopurinol in Inadequate Responders (CLEAR 2)

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who have had an inadequate response to allopurinol.

Added 7 years ago

Search all clinical trials for Gout