Latest news articles

Added 6 months ago Drug news

Kidney transplant patients experience higher rates of uncontrolled gout compared to other renal disease patients. Horizon Pharma

Horizon Pharma plc announced multiple presentations showing that people who have undergone a kidney transplant experience higher rates of uncontrolled...

Added 8 months ago Drug news

European Commission approves Duzallo to treat gout.- Grunenthal.

GrĂ¼nenthal announced that the European Commission has followed the positive opinion of the Committee for Medicinal Products for Human Use...

Added 10 months ago Drug news

CHMP recommends approval of Duzallo for hyperuricaemia in gout.- Gruenenthal.

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation...

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Guidelines

The British Society for Rheumatology Guideline for the Management of Gout

This guideline aims to offer revised and updated, concise, patient-focused, evidence-based, expert recommendations for the management of gout in the UK.

Added 1 year ago

2016 updated EULAR evidence-based recommendations for the management of gout

These recommendations aim to inform physicians and patients about the non-pharmacological and pharmacological treatments for gout and to provide the best strategies to achieve the predefined urate target to cure the disease.

Added 11 months ago

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Journal articles

The Effect of Lesinurad in Combination With Allopurinol on Serum Uric Acid Levels in Patients With Gout.

The objective of the study was to evaluate the effect of lesinurad, a selective uric acid uptake inhibitor, alone and in combination with the xanthine oxidase inhibitor allopurinol, on serum uric acid and urinary urate excretion in patients with...

Added 8 months ago

Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study).

Objectives: Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised, phase III trial.

Added 8 months ago

Chronic Disease Approaches Needed to Curb Gout’s Growing Burden.

Gout’s bad rap as disease of dietary excess has sometimes obscured the complex, chronic nature of the disease and led to ineffective care for many patients.

Added 10 months ago

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Clinical trials

Combining Lesinurad With Allopurinol in Inadequate Responders (CLEAR 1)

This study that compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who have had an inadequate response to allopurinol.

Added 8 years ago

Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat (CRYSTAL)

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with febuxostat...

Added 8 years ago

Combining Lesinurad With Allopurinol in Inadequate Responders (CLEAR 2)

This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with allopurinol to allopurinol alone in subjects with gout who have had an inadequate response to allopurinol.

Added 8 years ago

Search all clinical trials for Gout