Latest news articles

Added 1 month ago Drug news

EU approves Lokelma to treat hyperkalaemia.- AstraZeneca.

AstraZeneca announced that the European Commission has granted marketing authorisation for Lokelma (formerly ZS-9, sodium zirconium cyclosilicate) for the treatment...

Added 5 months ago Drug news

Ardelyx, to discontinue development of RDX 7675 for the treatment of hyperkalemia.

Ardelyx, Inc. provided an update on the development of its cardiorenal pipeline. The company's second registration study for tenapanor for...

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Fluid Management

Fluid Management

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Intravenous fluid therapy in children and young people in hospital

This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing...

Added 2 years ago

Clinical practice guideline on diagnosis and treatment of hyponatraemia

The European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association–European Dialysis...

Added 4 years ago

EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis.

Ascites is the most common complication of cirrhosis, and ∼60% of patients with compensated cirrhosis develop ascites within 10 years during the course of their disease. 

Added 1 year ago

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Journal articles

Non-oncotic properties of albumin. A multidisciplinary vision about the implications for critically ill patients.

Effective resuscitation with human albumin solutions is achieved with less fluid than with crystalloid solutions. However, the role of albumin in today's critical care unit is also linked to its multiple pharmacological effects.

Added 1 month ago

Expert Panel Recommendations for the Identification and Management of Hyperkalemia and Role of Patiromer in Patients with Chronic Kidney Disease and Heart Failure.

Virtual panel meetings were conducted among 7 physicians, all of whom are independent experts, including 3 nephrologists, 2 cardiologists, and 2 emergency medicine physicians (the panel).

Added 7 months ago

Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial.

The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown.

Added 7 months ago

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Clinical trials

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)

The purpose of this study was to evaluate the efficacy and safety of patiromer (investigational drug) in the treatment of hyperkalemia (high serum potassium).

Added 7 months ago

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