Data from multiple sources - Curated by EPG Health - Last updated 06 June 2017

Latest news articles

Added 3 months ago Drug news

Ardelyx, to discontinue development of RDX 7675 for the treatment of hyperkalemia.

Ardelyx, Inc. provided an update on the development of its cardiorenal pipeline. The company's second registration study for tenapanor for...

Added 7 months ago Drug news

NICE extends recommendation for Strensiq (asfotase alfa) to treat people with paediatric-onset hypophosphatasia.- Alexion Pharma

NICE has published draft guidance recommending the drug asfotase alfa (also called Strensiq and made by Alexion Pharma UK) for...

Added 9 months ago Drug news

EU CHMP recommends approval of Veltassa (patiromer) for the treatment of hyperkalaemia- Vifor Fresenius

The EU Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Intravenous fluid therapy in children and young people in hospital

This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing...

Added 2 years ago

Clinical practice guideline on diagnosis and treatment of hyponatraemia

The European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association–European Dialysis...

Added 4 years ago

EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis.

Ascites is the most common complication of cirrhosis, and ∼60% of patients with compensated cirrhosis develop ascites within 10 years during the course of their disease...

Added 1 year ago

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Journal articles

Expert Panel Recommendations for the Identification and Management of Hyperkalemia and Role of Patiromer in Patients with Chronic Kidney Disease and Heart Failure.

Virtual panel meetings were conducted among 7 physicians, all of whom are independent experts, including 3 nephrologists, 2 cardiologists, and 2 emergency medicine physicians (the panel).

Added 5 months ago

Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial.

The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown.

Added 5 months ago

Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial.

The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown.

Added 5 months ago

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Clinical trials

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)

The purpose of this study was to evaluate the efficacy and safety of patiromer (investigational drug) in the treatment of hyperkalemia (high serum potassium).

Added 5 months ago

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