Latest news articles
Added 1 month ago Drug news
FDA approves Lokelma to treat hyperkalaemia.-AstraZeneca.
The FDA has approved Lokelma (sodium zirconium cyclosilicate), formerly ZS-9, for the treatment of adults with hyperkalaemia, a serious condition...
Added 1 month ago Drug news
FDA accepts sNDA for Veltassa in hyperkalemia.- Relypsa.
Relypsa announced that the FDA has approved a supplemental New Drug Application (sNDA) for Veltassa (patiromer) for oral suspension in...
Added 2 months ago Drug news
EU approves Lokelma to treat hyperkalaemia.- AstraZeneca.
AstraZeneca announced that the European Commission has granted marketing authorisation for Lokelma (formerly ZS-9, sodium zirconium cyclosilicate) for the treatment...
Learning Zones
An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.
Fluid Management
Are you up-to-date with the latest evidence of effective procedures for fluid management?
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Transplantation
See information on best practice in solid organ transplantation, and expert discussions on related hot topics.
Breakthrough Cancer Pain Learning Zone
Watch video highlights from the BeCOn OWN 2017 event, including expert opinion, patient experience and panel discussions in the Breakthrough Cancer Pain Learning Zone.
Pain, Agitation and Delirium (PAD) Management
Discover the latest guidance on assessment and management of pain, agitation and delirium for patients requiring sedation.
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Oral Anticoagulation Reversal
Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.
Cystic Fibrosis Knowledge Centre
View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.
Fabry Disease
Explore the pathophysiology and treatment options for Fabry disease, a deficiency of the lysosomal enzyme alpha-galactosidase A
Guidelines
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
The following Clinical Practice Guidelines (CPGs) represent the first CPGs on the management of decompensated cirrhosis.
Added 4 days ago
Intravenous fluid therapy in children and young people in hospital
This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing...
Added 2 years ago
Clinical practice guideline on diagnosis and treatment of hyponatraemia
The European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association–European Dialysis...
Added 4 years ago
Journal articles
Non-oncotic properties of albumin. A multidisciplinary vision about the implications for critically ill patients.
Effective resuscitation with human albumin solutions is achieved with less fluid than with crystalloid solutions. However, the role of albumin in today's critical care unit is also linked to its multiple pharmacological effects.
Added 3 months ago
Expert Panel Recommendations for the Identification and Management of Hyperkalemia and Role of Patiromer in Patients with Chronic Kidney Disease and Heart Failure.
Virtual panel meetings were conducted among 7 physicians, all of whom are independent experts, including 3 nephrologists, 2 cardiologists, and 2 emergency medicine physicians (the panel).
Added 9 months ago
Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial.
The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown.
Added 9 months ago
Clinical trials
A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)
The purpose of this study was to evaluate the efficacy and safety of patiromer (investigational drug) in the treatment of hyperkalemia (high serum potassium).
Added 9 months ago