Latest news articles

Added 1 month ago Drug news

HARMONIZE Global Phase III trial results for Lokelma presented at ASN Kidney Week.- AstraZeneca.

AstraZeneca presented the results from the HARMONIZE Global Phase III trial, which investigated the safety and efficacy of Lokelma (sodium...

Added 6 months ago Drug news

FDA approves Lokelma to treat hyperkalaemia.-AstraZeneca.

The FDA has approved Lokelma (sodium zirconium cyclosilicate), formerly ZS-9, for the treatment of adults with hyperkalaemia, a serious condition...

Added 7 months ago Drug news

FDA accepts sNDA for Veltassa in hyperkalemia.- Relypsa.

Relypsa announced that the FDA has approved a supplemental New Drug Application (sNDA) for Veltassa (patiromer) for oral suspension in...

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Fluid Management

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EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

The following Clinical Practice Guidelines (CPGs) represent the first CPGs on the management of decompensated cirrhosis.

Added 5 months ago

Intravenous fluid therapy in children and young people in hospital

This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing...

Added 3 years ago

Clinical practice guideline on diagnosis and treatment of hyponatraemia

The European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association–European Dialysis...

Added 4 years ago

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Journal articles

Non-oncotic properties of albumin. A multidisciplinary vision about the implications for critically ill patients.

Effective resuscitation with human albumin solutions is achieved with less fluid than with crystalloid solutions. However, the role of albumin in today's critical care unit is also linked to its multiple pharmacological effects.

Added 9 months ago

Expert Panel Recommendations for the Identification and Management of Hyperkalemia and Role of Patiromer in Patients with Chronic Kidney Disease and Heart Failure.

Virtual panel meetings were conducted among 7 physicians, all of whom are independent experts, including 3 nephrologists, 2 cardiologists, and 2 emergency medicine physicians (the panel).

Added 1 year ago

Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial.

The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown.

Added 1 year ago

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Clinical trials

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)

The purpose of this study was to evaluate the efficacy and safety of patiromer (investigational drug) in the treatment of hyperkalemia (high serum potassium).

Added 1 year ago

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