Latest news articles

Added 2 days ago Drug news

Positive interim results from ORION-3 study of inclisiran twice yearly dosing for LDL patients

The Medicines Company announced interim results from the ongoing ORION-3 open-label extension study (Group 1, n=290) which showed that twice-a-year...

Added 2 months ago Drug news

Phase III CLEAR Wisdom study of ETC 1002 shows safe profile in dyslipidaemia

Daiichi Sankyo and Esperion announced that data from the Phase III CLEAR Wisdom study of ETC 1002 (bempedoic acid) highlighted...

Added 2 months ago Drug news

REDUCE-IT study shows Vascepa can provide a 30% risk reduction in total CV events

Amarin Corporation plc presented new data from its landmark cardiovascular outcomes study of its prescription therapy, Vascepa (icosapent ethyl), the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Acute and Advanced Heart Failure

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

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Guidelines

Cardiovascular disease: risk assessment and reduction, including lipid modification

This guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease and stroke. It aims to help healthcare professionals identify people who are at risk of...

Added 4 years ago

2016 ESC/EAS guidelines for the management of dyslipidaemias

The present Guidelines represent an evidence-based consensus, by appraising the current evidence and indentifying remaining knowledge gaps in managing the prevention of dyslipIdaemias...

Added 2 years ago

KDIGO Clinical Practice Guideline for Lipid Management in Chronic Kidney Disease

The 2013 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Lipid Management in Chronic Kidney Disease (CKD) provides guidance on lipid management and treatment for all patients with CKD...

Added 5 years ago

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Journal articles

Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis.

Objective: To evaluate whether baseline LDL-C level is associated with total and cardiovascular mortality risk reductions.

Added 8 months ago

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.

Objective: To evaluate efficacy and safety of further lowering LDL-C levels in patient populations presenting with median LDL-C levels of 1.8 mmol/L (70 mg/dL) or less.

Added 8 months ago

Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy.

In this review, the effect and safety of an approved combination therapy with simvastatin plus fenofibrate are described, with an analysis of pros and cons resulting from randomized multicenter trials, meta-analyses...

Added 10 months ago

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Clinical trials

A Study in Subjects With Type 2 Diabetes Mellitus With Hypercholesterolemia/Mixed Dyslipidemia

The purpose of this study is to evaluate the effect of 12 weeks of subcutaneous evolocumab taken monthly compared with subcutaneous placebo taken monthly on low density lipoprotein cholesterol (LDL-C) in subjects with...

Added 10 months ago

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