Latest news articles

Added 1 day ago Drug news

Phase III CLEAR Wisdom study of ETC 1002 shows safe profile in dyslipidaemia

Daiichi Sankyo and Esperion announced that data from the Phase III CLEAR Wisdom study of ETC 1002 (bempedoic acid) highlighted...

Added 2 days ago Drug news

REDUCE-IT study shows Vascepa can provide a 30% risk reduction in total CV events

Amarin Corporation plc presented new data from its landmark cardiovascular outcomes study of its prescription therapy, Vascepa (icosapent ethyl), the...

Added 6 days ago Drug news

Phase III results for ETC 1002 in dyslipidaemia published in NEJM

Daiichi Sankyo and Esperion Therapeutics announced that results from the 2,230 patient, 52-week, Phase III long-term safety study of ETC...

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Learning Zones

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Acute and Advanced Heart Failure

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

Cardiovascular disease: risk assessment and reduction, including lipid modification

This guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease and stroke. It aims to help healthcare professionals identify people who are at risk of...

Added 4 years ago

2016 ESC/EAS guidelines for the management of dyslipidaemias

The present Guidelines represent an evidence-based consensus, by appraising the current evidence and indentifying remaining knowledge gaps in managing the prevention of dyslipIdaemias...

Added 2 years ago

KDIGO Clinical Practice Guideline for Lipid Management in Chronic Kidney Disease

The 2013 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Lipid Management in Chronic Kidney Disease (CKD) provides guidance on lipid management and treatment for all patients with CKD...

Added 5 years ago

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Journal articles

Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis.

Objective: To evaluate whether baseline LDL-C level is associated with total and cardiovascular mortality risk reductions.

Added 6 months ago

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.

Objective: To evaluate efficacy and safety of further lowering LDL-C levels in patient populations presenting with median LDL-C levels of 1.8 mmol/L (70 mg/dL) or less.

Added 6 months ago

Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy.

In this review, the effect and safety of an approved combination therapy with simvastatin plus fenofibrate are described, with an analysis of pros and cons resulting from randomized multicenter trials, meta-analyses...

Added 8 months ago

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Clinical trials

A Study in Subjects With Type 2 Diabetes Mellitus With Hypercholesterolemia/Mixed Dyslipidemia

The purpose of this study is to evaluate the effect of 12 weeks of subcutaneous evolocumab taken monthly compared with subcutaneous placebo taken monthly on low density lipoprotein cholesterol (LDL-C) in subjects with...

Added 8 months ago

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