Data from multiple sources - Curated by Marshall Pearce - Last updated 06 June 2017

Diabetes mellitus with complications

The global population living with diabetes was estimated at 108 million in 1980, while World Health Organisation figures for 2014 have shown that has nearly quadrupled to 422

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Latest news articles

Added 1 month ago Drug news

Diabetes approval for Ozempic

CHMP recommends approval of Ozempic for type 2 diabetes.

Added 1 month ago Drug news

Type 2 diabetes: real world data shows reduced blood sugar levels in patients treated with Xultophy

EXTRA study data on Xultophy in type 2 diabetes published in Diabetes, Obesity and Metabolism

Added 1 month ago Drug news

Short-acting insulin indicated to improve control in blood sugar

FDA approves Admelog for diabetes

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Type 2 Diabetes

Type 2 Diabetes

View the latest epidemiology data, patient perspectives, ADA and EASD recommendations, treatment options and more.

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Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity.

Development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and the American College of Endocrinology...

Added 1 year ago

Type 2 diabetes: The management of type 2 diabetes

This guideline contains recommendations for managing type 2 diabetes in adults, and focuses on patient education, dietary advice, managing cardiovascular...

Added 2 years ago

Diabetes (type 1 and type 2) in children and young people: diagnosis and management

This guideline updates and replaces the sections for children and young people in type 1 diabetes (NICE guideline CG15). This...

Added 2 years ago

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Journal articles

Canagliflozin: A Review in Type 2 Diabetes.

Canagliflozin (Invokana®) is a sodium-glucose co-transporter-2 (SGLT2) inhibitor indicated in various countries worldwide for the once-daily oral treatment of type 2 diabetes (T2D).

Added 2 months ago

Achieving the composite endpoint of HbA1c, body weight, and systolic blood pressure reduction with canagliflozin in patients with type 2 diabetes.

Objective: In addition to achieving glycemic control, weight loss and blood pressure reduction are important components of type 2 diabetes mellitus management, as many patients with T2DM are overweight/obese and/or have hypertension.

Added 2 months ago

Increased amputation risk with canagliflozin treatment: behind the large cardiovascular benefit?

A growing body of evidence suggests that sodium-glucose cotransporter 2 (SGLT2) inhibitors appear to be a powerful option to improve the cardiovascular (CV) prognosis in high CV-risk patients with type 2 diabetes.

Added 2 months ago

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Clinical trials

CARAT: Canagliflozin vs. placebo for post bariatric patients with persistent type 2 diabetes

This is a prospective, randomized clinical trial for patients with recurrent type 2 diabetes post-gastric bypass surgery that will compare a 6 month course of canagliflozin monotherapy vs. placebo on clinical outcomes of type 2 diabetes.

Added 1 year ago

Investigating the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus (EU-TREAT)

This trial is conducted in Europe. The aim of this trial is to investigate the effectiveness of Tresiba® (insulin degludec) after switching basal insulin in a population with type 1 or type 2 diabetes mellitus.

Added 2 months ago

Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy (CREDENCE)

The goal of this study is to assess whether canagliflozin has a renal and vascular protective effect in reducing the progression of renal impairment relative to placebo in participants with type 2 diabetes mellitus (T2DM)...

Added 2 months ago

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Robin Hewings

Robin Hewings is the Head of Policy at Diabetes UK. The team find and interpret data, develop policy recommendations and then try to persuade politicians and the public of our case. Mostly working in health, he has been putting together evidence and communications for the last 15 years in ... Read more

Diabetes Patients Must Be Better Educated About Their Condition

Not everyone is convinced that education courses help people look after their diabetes. And the GP I was chatting to a couple of months ago was one of them. He wasn’t sure they worked. People didn’t seem that interested and he wasn’t really sure what people would learn anyway.

CME

Step by step: how to diagnose and manage type 1 diabetes in adults in primary care

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Clinical pointers: Blood glucose control in type 2 diabetes

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Clinical pointers: recognising and managing acute complications of diabetes in adults

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