Added 4 months ago Drug news

Kalydeco is FDA approved for use in cystic fibrosis patients ages 2 and older who have one of 23 residual function mutations in the CFTR gene.- Vertex Pharma

Vertex Pharmaceuticals Incorporated announced that the FDA has approved Kalydeco (ivacaftor) for use in people with cystic fibrosis (CF) ages...

Added 5 months ago Drug news

Two Phase III studies reported of tezacaftor (VX-661) / ivacaftor combination of cystic fibrosis transmembrane conductance regulator (CFTR) gene affected patients.-Vertex

Vertex Pharmaceuticals Incorporated announced results from two Phase III studies of the tezacaftor (VX-661) / ivacaftor combination treatment that showed...

Added 6 months ago Drug news

Vertex Pharmaceuticals to acquire CTP 656, a proposed treatment for cystic fibrosis from Concert Pharmaceuticals.

Vertex Pharmaceuticals Incorporated announced that it has signed a definitive asset purchase agreement to acquire CTP 656 from Concert Pharmaceuticals...

European Cystic Fibrosis Society Standards of Care: Best Practice guidelines

Specialised CF care has led to a dramatic improvement in survival in CF: in the last four decades, well above...

Added 3 years ago

Culture-based diagnostic microbiology in cystic fibrosis: Can we simplify the complexity?

This review summarizes state-of-the art culture methods and makes recommendations for addition of non-culture based methods in the diagnostic laboratory.

Added 4 years ago

Consensus statement for inert gas washout measurement using multiple- and single-breath tests

Inert gas washout tests, performed using the single- or multiple-breath washout technique, were first described over 60 years ago. As...

Added 5 years ago

Genetic Influences on Cystic Fibrosis Lung Disease Severity

Understanding the causes of variation in clinical manifestations of disease should allow for design of new or improved therapeutic strategies to treat the disease. If variation is caused by genetic...

Added 4 months ago

Cystic fibrosis: genotypic and phenotypic variations.

Cystic fibrosis (CF) is a common genetic disorder in the Caucasian population. The gene was identified in 1989 on the basis of its map location on chromosome 7.

Added 7 months ago

Decade-long bacterial community dynamics in cystic fibrosis airways.

The structure and dynamics of bacterial communities in the airways of persons with cystic fibrosis (CF) remain largely unknown.

Added 7 months ago