Latest news articles

Added 26 days ago Drug news

EPOCH 2 Phase III study of HTX 011 in pain control published in Hernia journal

Heron Therapeutics announced that the results from EPOCH 2, a Phase III study of the investigational agent HTX 011 (bupivacaine...

Added 1 month ago Drug news

FDA agrees to filing of the full response to the Posimir Complete Response Letter as a complete class 2 resubmission. DURECT Corporation

DURECT Corporation announced that the FDA has acknowledged that the submission of DURECT's full response to the Complete Response Letter...

Added 2 months ago Drug news

Durect Corporation files response to Complete Response Letter for treatment of post surgical pain

DURECT Corporation announced it has submitted a full response to the Complete Response Letter (CRL) it previously received from FDA...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

ESICM LIVES Highlights

ESICM LIVES Highlights

ESICM LIVES Congress 2018: Bringing you the latest news and insights from the 31st ESICM LIVES Congress, 20–24 October 2018 Paris, France.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart R

The scope of this focused update of the 2014 AF Guideline includes revisions to the section on anticoagulation (because of the approval of new medications and thromboembolism protection devices), revisions to the section...

Added 1 month ago

Urinary incontinence and pelvic organ prolapse in women: management

This guideline covers assessing and managing urinary incontinence and pelvic organ prolapse in women aged 18 and over. It also covers complications associated with mesh surgery for these conditions.

Added 1 month ago

Surgical site infections: prevention and treatment

This guideline covers preventing and treating surgical site infections in adults, young people and children who are having a surgical procedure involving a cut through the skin.

Added 10 years ago

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Journal articles

Clinical Management of Adverse Events Associated with Lorlatinib.

Lorlatinib is a novel, highly potent, brain‐penetrant, third‐generation ALK/ROS1 tyrosine kinase inhibitor (TKI), which has broad‐spectrum potency against most known resistance mutations that can develop during treatment with...

Added 3 days ago

Reversal agents for direct oral anticoagulants: considerations for hospital physicians and intensivists.

Direct oral anticoagulants (DOACs) include dabigatran etexilate, a direct thrombin inhibitor, and specific inhibitors of activated coagulation factor X (FXa; e.g. apixaban, betrixaban, edoxaban, rivaroxaban).

Added 11 days ago

Low preoperative fibrinogen plasma concentration is associated with excessive bleeding after cardiac operations.

Background: Data from small selected patient populations suggest that the preoperative plasma concentration of fibrinogen influences postoperative blood loss and red blood cell transfusion after cardiac operations, but there are...

Added 3 months ago

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Clinical trials

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement (HYPALB)

The primary objective of this study is to test the effect of 20% albumin on plasma volume expansion and fluid recruitment in the frame of blood loss replacement during cystectomy using established fluid kinetic models.

Added 5 months ago

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 1 year ago

PeproStat as a Topical Agent Used to Stop Bleeding in Patients Undergoing Surgery

The purpose of this study is to test the effectiveness and safety of a new peptide-based coagulant, PeproStat. The study drug will be applied to patients undergoing liver/soft tissue surgery, vascular surgery or spine surgery.

Added 1 year ago

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Jonathan Macdonald

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

CME

What's new in chronic heart failure

Accrediting body
BMJ Learning - British Medical Learning
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90

Step by step: A guide to diagnosing heart failure

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Palliative care in patients with heart failure

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
Search all CME for Complications of surgical procedures or medical care