Latest news articles

Added 4 days ago Drug news

FDA agrees to filing of the full response to the Posimir Complete Response Letter as a complete class 2 resubmission. DURECT Corporation

DURECT Corporation announced that the FDA has acknowledged that the submission of DURECT's full response to the Complete Response Letter...

Added 24 days ago Drug news

Durect Corporation files response to Complete Response Letter for treatment of post surgical pain

DURECT Corporation announced it has submitted a full response to the Complete Response Letter (CRL) it previously received from FDA...

Added 25 days ago Drug news

Study of Exparel in post surgical pain shows reduced opioid usage after dental surgery

Pacira BioSciences announced results of a new analysis of patients undergoing elective third molar extraction with at least one bony...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

ESICM LIVES Highlights

ESICM LIVES Highlights

ESICM LIVES Congress 2018: Bringing you the latest news and insights from the 31st ESICM LIVES Congress, 20–24 October 2018 Paris, France.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Added 9 months ago

UK guidelines on oesophageal dilatation in clinical practice

These guidelines deal specifically with the dilatation procedure using balloon or bougie devices as a primary treatment strategy for non-malignant narrowing of the oesophagus.

Added 1 year ago

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

VTE is a condition in which a blood clot (thrombus) forms in a vein. It most commonly occurs in the...

Added 9 years ago

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Journal articles

Low preoperative fibrinogen plasma concentration is associated with excessive bleeding after cardiac operations.

Background: Data from small selected patient populations suggest that the preoperative plasma concentration of fibrinogen influences postoperative blood loss and red blood cell transfusion after cardiac operations, but there are...

Added 1 month ago

Morbidity of bleeding after cardiac surgery: is it blood transfusion, reoperation for bleeding, or both?

Background: Etiology for increased morbidity in patients (2% to 8%) undergoing reoperation for bleeding after cardiac surgery is unclear. Recent work suggests that it may be related to red-cell transfusion, but what role does...

Added 1 month ago

Early activation of hemostasis during cardiopulmonary bypass: evidence for thrombin mediated hyperfibrinolysis.

In 14 consecutive patients undergoing cardiopulmonary bypass for coronary bypass surgery the time course of coagulation and fibrinolysis markers were measured, e. g. plasma levels of thrombin-antithrombin III (TAT) complexes...

Added 1 month ago

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Clinical trials

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement (HYPALB)

The primary objective of this study is to test the effect of 20% albumin on plasma volume expansion and fluid recruitment in the frame of blood loss replacement during cystectomy using established fluid kinetic models.

Added 4 months ago

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 1 year ago

PeproStat as a Topical Agent Used to Stop Bleeding in Patients Undergoing Surgery

The purpose of this study is to test the effectiveness and safety of a new peptide-based coagulant, PeproStat. The study drug will be applied to patients undergoing liver/soft tissue surgery, vascular surgery or spine surgery.

Added 1 year ago

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Jonathan Macdonald

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

CME

What's new in chronic heart failure

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BMJ Learning - British Medical Learning
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90

Step by step: A guide to diagnosing heart failure

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BMJ Learning - British Medical Learning
Credits available
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1
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90

Palliative care in patients with heart failure

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
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