Latest news articles

Added 2 days ago Drug news

Phase III EPOCH 1 study of HTX 011 in bunionectomy published in Regional Anesthesia & Pain Medicine

Heron Therapeutics announced that the results from the pivotal Phase III EPOCH 1 bunionectomy study of the investigational agent HTX...

Added 16 days ago Drug news

Phase IV study of Exparel shows reduction in opioid use after surgery

Pacira BioSciences announced that full results from its Phase IV study of Exparel (bupivacaine liposome injectable suspension) administered via transversus...

Added 22 days ago Drug news

HTX 011 has complete response letter from FDA for management of postoperative pain

Heron Therapeutics, Inc. announced that it received a Complete Response Letter (CRL) from the FDA on April 30, 2019 regarding...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

ESICM LIVES Highlights

ESICM LIVES Highlights

ESICM LIVES Congress 2018: Bringing you the latest news and insights from the 31st ESICM LIVES Congress, 20–24 October 2018 Paris, France.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Added 7 months ago

UK guidelines on oesophageal dilatation in clinical practice

These guidelines deal specifically with the dilatation procedure using balloon or bougie devices as a primary treatment strategy for non-malignant narrowing of the oesophagus.

Added 11 months ago

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

VTE is a condition in which a blood clot (thrombus) forms in a vein. It most commonly occurs in the...

Added 9 years ago

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Journal articles

Plasma fibrinogen level on admission to the intensive care unit is a powerful predictor of postoperative bleeding after cardiac surgery with cardiopulmonary bypass.

Introduction: Evidence regarding the behavior of fibrinogen levels and the relation between fibrinogen levels and postoperative bleeding is limited in cardiac surgery under cardiopulmonary bypass (CPB).

Added 1 day ago

The influence of perioperative coagulation status on postoperative blood loss in complex cardiac surgery: a prospective observational study.

Introduction: Coagulopathy leading to excessive blood loss is a serious complication of cardiac surgery. In this prospective cohort study, we measured patients' coagulation status before and after cardiopulmonary bypass (CPB)...

Added 1 day ago

Management of bleeding in vascular surgery.

Management of acute coagulopathy and blood loss during major vascular procedures poses a significant haemostatic challenge to anaesthetists. The acute coagulopathy is multifactorial in origin with tissue injury and hypotension as...

Added 2 days ago

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Clinical trials

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement (HYPALB)

The primary objective of this study is to test the effect of 20% albumin on plasma volume expansion and fluid recruitment in the frame of blood loss replacement during cystectomy using established fluid kinetic models.

Added 2 months ago

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 1 year ago

PeproStat as a Topical Agent Used to Stop Bleeding in Patients Undergoing Surgery

The purpose of this study is to test the effectiveness and safety of a new peptide-based coagulant, PeproStat. The study drug will be applied to patients undergoing liver/soft tissue surgery, vascular surgery or spine surgery.

Added 1 year ago

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Jonathan Macdonald

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

CME

What's new in chronic heart failure

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BMJ Learning - British Medical Learning
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Step by step: A guide to diagnosing heart failure

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BMJ Learning - British Medical Learning
Credits available
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1
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90

Palliative care in patients with heart failure

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
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90
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